2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Estrogen Receptor/ERR
  5. Estrogen Receptor/ERR Agonist

Estrogen Receptor/ERR Agonist

Estrogen Receptor/ERR Isoform Comparison

Estrogen Receptor/ERR Agonists (94):

Cat. No. Product Name Effect Purity
  • HY-138690
    Estrogen receptor modulator 6
    		Agonist
    Estrogen receptor modulator 6 (compound 3a) is a selective estrogen receptor (ER) β agonist (Ki=0.44 nM). Estrogen receptor modulator 6 displays 19-fold selectivity for ERβ over ERα(Ki=8.4 nM).
  • HY-123047
    Tibolone
    		Agonist 99.68%
    Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research.
  • HY-B1176R
    Equilin (Standard)
    		Agonist
    Equilin (Standard) is the analytical standard of Equilin. This product is intended for research and analytical applications. Equilin (7-Dehydroestrone) is an important member of the large group of oestrogenic substances and is chemically related to menformon (oestrone). Equilin increases the growth of cortical neurons via an NMDA receptor-dependent mechanism.
  • HY-B1012R
    Quinestrol (Standard)
    		Agonist
    Quinestrol (Standard) is the analytical standard of Quinestrol. This product is intended for research and analytical applications. Quinestrol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • HY-107803
    Geranium oil
    		Agonist
    Geranium oil serves as a partial agonist for estrogen receptor (ER), enhancing both the cytotoxicity induced by Tamoxifen (TMX) (HY-13757A) in GT1-7 cells and the adverse effects of TMX on the central nervous system. Geranium oil can be utilized in the research of neurological disorders such as dementia.
  • HY-126932
    TTC-352
    		Agonist
    TTC-352 is an orally bioavailable selective human estrogen receptor (ER) α partial agonist (ShERPA). TTC-352 inhibits the growth of three ER+ breast cancer cells. TTC-352 induces tumor regression accompanied by exit of ERα from the nucleus to extranuclear sites.
  • HY-B1662R
    Hexestrol (Standard)
    		Agonist
    Hexestrol (Standard) is the analytical standard of Hexestrol. This product is intended for research and analytical applications. Hexestrol is a nonsteroidal synthetic estrogen, with a Ki of 0.06 and 0.06 nM for estrogen receptor alpha (ERα) and ERβ. Hexestrol can be used for the research of the diseases caused by estrogen deficiencym, and it also can increase the weight of cattle.
  • HY-108293R
    Promestriene (Standard)
    		Agonist
    Promestriene (Standard) is the analytical standard of Promestriene. This product is intended for research and analytical applications. Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed.
  • HY-163712
    17-Epiestriol
    		Agonist
    17-Epiestriol is an estrogen metabolite and a selective estrogen receptor (ER) β agonist. 17-epiestriol inhibits the mRNA and protein expression of the vascular cell adhesion molecule VCAM-1 induced by tumor necrosis factor α (TNFα). 17-epiestriol also inhibits TNFα-induced VCAM-1 expression and prevents NF-κB migration to the nucleus. 17-Epiestriol also induces the mRNA and protein expression of endothelial nitric oxide synthase.
  • HY-B0141C
    Estradiol hemihydrate
    		Agonist
    Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering.
  • HY-151230
    (-)-Erteberel
    		Agonist
    (-)-Erteberel is a selective estrogen receptor beta (ERβ) agonist. (-)-Erteberel can be utilized in the study of diseases mediated by estrogen receptor beta (ERβ), such as prostate cancer.
  • HY-164463
    BMI-135
    		Agonist
    BMI-135 is a selective estrogen mimic, that exhibits agonist activity for estrogen receptor. BMI-135 induces rapid endoplasmic reticulum stress response (UPR) and apoptosis in breast cancer cells.
  • HY-B0390R
    Mestranol (Standard)
    		Agonist
    Mestranol (Standard) is the analytical standard of Mestranol. This product is intended for research and analytical applications. Mestranol is an inactive proagent and becomes biologically active on conversion to ethinyl estradiol (EE). Mestranol acts as an estrogen receptor agonist. Mestranol combines with a progestin in vivo and can be used for the research of menopausal hormone or menstrual disorders. Mestranol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • HY-U00216
    NNC45-0781
    		Agonist
    NNC45-0781 is a tissue-selective estrogen partial-agonist.