2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. TTC-352

TTC-352 is an orally bioavailable selective human estrogen receptor (ER) α partial agonist (ShERPA). TTC-352 inhibits the growth of three TR ER+ breast cancer cell cultures in 3D. TTC-352 induces tumor regression accompanied by exit of ERα from the nucleus to extranuclear sites, mimicking the actions of E2.

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TTC-352 Chemical Structure

TTC-352 Chemical Structure

CAS No. : 1607819-68-0

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TTC-352 Related Antibodies

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Description

TTC-352 is an orally bioavailable selective human estrogen receptor (ER) α partial agonist (ShERPA). TTC-352 inhibits the growth of three TR ER+ breast cancer cell cultures in 3D. TTC-352 induces tumor regression accompanied by exit of ERα from the nucleus to extranuclear sites, mimicking the actions of E2[1][2].

Molecular Weight

352.38

Formula

C20H13FO3S
CAS No.
SMILES

OC1=CC=C(C(C2=CC=C(F)C=C2)=C(OC3=CC=C(O)C=C3)S4)C4=C1
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Storage

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Purity & Documentation
References
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TTC-352 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TTC-3521607819-68-0TTC352TTC 352Estrogen Receptor/ERRERbreast cancer celltumor regressionE2Inhibitorinhibitorinhibit

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