2. Gene
  3. RAF1 - Raf-1 proto-oncogene, serine/threonine kinase Gene

RAF1 - Raf-1 proto-oncogene, serine/threonine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100737448 | Gene type: protein coding

About RAF1

Primary_assembly 13: 68,580,812-68,657,829 reverse strand.Sscrofa11.1:CM000824.5

This gene has 3 transcripts (splice variants), 219 orthologues and 23 paralogues. Ubiquitous expression in longissimus dorsi muscle (RPKM 4.3), psoas major muscle (RPKM 36.2) and 8 other tissues.

RAF1 Products(6)

mRNA Protein Name
XM_021069349.1 XP_020925008.1 RAF proto-oncogene serine/threonine-protein kinase isoform X1
XM_021069352.1 XP_020925011.1 RAF proto-oncogene serine/threonine-protein kinase isoform X2
XM_021069350.1 XP_020925009.1 RAF proto-oncogene serine/threonine-protein kinase isoform X2
XM_021069348.1 XP_020925007.1 RAF proto-oncogene serine/threonine-protein kinase isoform X1
XM_021069351.1 XP_020925010.1 RAF proto-oncogene serine/threonine-protein kinase isoform X2
XM_021069347.1 XP_020925006.1 RAF proto-oncogene serine/threonine-protein kinase isoform X1

RAF1 Protein Structure

RBD_CRAF

RBD_CRAF: cd17135 (54 - 130)

C1_A_C-Raf

C1_A_C-Raf: cd20870 (135 - 186)

STKc_C-Raf

STKc_C-Raf: cd14149 (355 - 637)

  • 0
  • 200
  • 400
  • 600
  • 668 a.a.
Protein Preferred Names Protein Names

RAF proto-oncogene serine/threonine-protein kinase

v-raf-1 murine leukemia viral oncogene homolog 1

Related Agents

Approval
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10201 Sorafenib 99.92% Yes
HY-12057 Vemurafenib 99.85% Yes
HY-10331 Regorafenib 99.93% Yes
HY-10201A Sorafenib Tosylate 99.91% Yes
HY-10201S Sorafenib-d3 99.57% Unkown
HY-10331A Regorafenib monohydrate 99.96% Yes
HY-13308 Regorafenib Hydrochloride 99.58% Yes
HY-10201R Sorafenib (Standard) 99.71% Unkown
HY-10331B Regorafenib mesylate / Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-134813 MRTX1133 Inhibitor 99.42% Phase 2
HY-114491 Rineterkib Inhibitor 99.83% Phase 2
Pre-clinical Phase
Bioactive Molecules (28)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-51424 PLX-4720 Inhibitor 99.91% Unkown
HY-11004 AZ 628 99.85% Unkown
HY-W013411A Locostatin Inhibitor 99.82% Unkown
HY-P1039A R18 TFA 99.91% Unkown
HY-18832 AWL-II-38.3 99.71% Unkown
HY-158107 BBO-8520 Inhibitor 99.90% Unkown
HY-122914 KRAS inhibitor-3 Inhibitor 99.65% Unkown
HY-I0678 Regorafénib N-oxyde (M2) 99.32% Unkown
HY-123673 MCP110 Inhibitor 99.82% Unkown
HY-136420 SJF-0628 Inhibitor 99.62% Unkown
HY-15716 Kobe0065 98.01% Unkown
HY-117737A RRD-251 99.94% Unkown
HY-114491A Rineterkib hydrochloride Inhibitor 99.81% Unkown
HY-15717 Kobe2602 Inhibitor 99.55% Unkown
HY-W013411 (E/Z)-Locostatin Inhibitor 99.52% Unkown
HY-P1039 R18 / Unkown
HY-10201S1 Sorafenib-d4 / Unkown
HY-10201S2 Sorafenib-13C,d3 98.35% Unkown
HY-10331S1 Regorafenib-13C,d3 / Unkown
HY-12057S1 Vemurafenib-d7 / Unkown
HY-161760 Ferroptosis inducer-3 Inhibitor / Unkown
HY-I0678S Regorafénib N-oxyde-d3 (M2) / Unkown
HY-I0678S1 Regorafénib N-oxyde (M2)-13C,d3 / Unkown
HY-RS11619 RAF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11620 Raf1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11621 Raf1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-12057S Vemurafenib-d5 / Unkown
HY-51424S PLX-4720-d7 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens RAF1 NCBI NCBI:5894