Pdxp - pyridoxal (pyridoxine, vitamin B6) phosphatase Gene

Mus musculus

Also known as PLPP; 1600027H05Rik

Gene ID: 57028 | Gene type: protein coding

About Pdxp

Summary

Enables magnesium ion binding activity; protein homodimerization activity; and pyridoxal Phosphatase activity. Involved in dephosphorylation and pyridoxal phosphate catabolic process. Located in cell-cell junction. Is expressed in alimentary system; eye; limb; nervous system; and tail. Orthologous to human PDXP (pyridoxal Phosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Pdxp Products(1)

mRNA	Protein	Name
NM_020271.3	NP_064667.2	chronophin

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables magnesium ion binding	IDA IDA: Inferred from direct assay	24338687	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	24338687	MGI
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	25783190	MGI
enables protein homodimerization activity	IPI IPI: Inferred from physical interaction	24338687	MGI
enables pyridoxal phosphatase activity	IDA IDA: Inferred from direct assay	24338473	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in dephosphorylation	IDA IDA: Inferred from direct assay	24338687	MGI
involved in pyridoxal phosphate catabolic process	IDA IDA: Inferred from direct assay	24338473	MGI
involved in pyridoxal phosphate catabolic process	IMP IMP: Inferred from mutant phenotype	30327125	MGI
involved in regulation of modification of postsynaptic structure	IDA IDA: Inferred from direct assay	27212638	MGI
involved in regulation of modification of postsynaptic structure	IMP IMP: Inferred from mutant phenotype	27212638	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell-cell junction	IDA IDA: Inferred from direct assay	23793062	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	27212638	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	27212638	MGI
is active in postsynapse	IDA IDA: Inferred from direct assay	27212638	MGI
is active in postsynapse	IMP IMP: Inferred from mutant phenotype	27212638	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

chronophin

PLP phosphatase	PLP-phosophatase
chronophilin	pyridoxal 5'-phosphate phosphatase
pyridoxal phosphate phosphatase

Recombinant Pdxp Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71768	PLP phosphatase Protein, Mouse (P.pastoris, His)	P60487 (1M-292D)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10298	PDXP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pdxp	NCBI	NCBI:57026

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