2. Academic Validation
  3. Isolation and Identification of Herbicidal Active Compounds from Brassica oleracea L. and Exploration of the Binding Sites of Brassicanate A Sulfoxide

Isolation and Identification of Herbicidal Active Compounds from Brassica oleracea L. and Exploration of the Binding Sites of Brassicanate A Sulfoxide

  • Plants (Basel). 2023 Jul 7;12(13):2576. doi: 10.3390/plants12132576.
Yu Wang 1,  Wanyou Liu 1,  Baozhu Dong 1,  Dong Wang 1,  Yin Nian 2,  Hongyou Zhou 1
Affiliations

Affiliations

  • 1 College of Horticulture and Plant Protection, Inner Mongolia Agricultural University, Hohhot 010020, China.
  • 2 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
PMID: 37447136 DOI: 10.3390/plants12132576
Abstract

Brassica oleracea L. has strong allelopathic effects on weeds. However, the allelochemicals with herbicidal activity in B. oleracea L. are still unknown. In this study, we evaluated the activity of allelochemicals isolated from Brassica oleracea L. based on the germination and growth of model plant Lactuca sativa Linn., grass weed Panicum miliaceum, and broadleaf weed Chenopodium album. Additionally, we employed molecular docking to predict the binding of brassicanate A sulfoxide to herbicide targets. The results of this study showed that eight compounds with herbicidal activity were isolated from B. oleracea L., and the predicted results indicated that brassicanate A sulfoxide was stably bound to dihydroxyacid dehydratase, hydroxymethylpyruvate dioxygenase, acetolactate synthase, PYL family proteins and transport inhibitor response 1. This research provides compound sources and a theoretical foundation for the development of natural herbicides.

Keywords

Brassica oleracea L.; activity guided; allelochemicals; herbicidal activity; molecule docking.

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