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Isoforms Recommended: FP
Results for "

PGF2α

" in MedChemExpress (MCE) Product Catalog:

88

Inhibitors & Agonists

6

Natural
Products

8

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12956
    Dinoprost
    2 Publications Verification

    Prostaglandin F2α; PGF2α

    		 Prostaglandin Receptor Endogenous Metabolite Autophagy Apoptosis Endocrinology
    Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour [2].
    Dinoprost
  • HY-12956A
    Dinoprost tromethamine salt
    2 Publications Verification

    Prostaglandin F2α tromethamine salt; PGF2α THAM; Prostaglandin F2α THAM

    		 Prostaglandin Receptor Endogenous Metabolite Autophagy Apoptosis Endocrinology
    Dinoprost tromethamine salt (Prostaglandin F2α tromethamine salt) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost tromethamine salt is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost tromethamine salt plays a key role in the onset and progression of labour [2].
    Dinoprost tromethamine salt
  • HY-118648
    Prostaglandin F2α methyl ester

    PGF2α methyl ester; Dinoprost methyl

    		 Others Others
    Prostaglandin F2α methyl ester (PGF2α methyl ester; Dinoprost methyl) is a PGF2α analog with more lipid solubility. Prostaglandin F2α methyl ester exhibits efficacy in maintaining the ocular hypotensive .
    Prostaglandin F2α methyl ester
  • HY-116549
    Prostaglandin F2α alcohol

    PGF2α alcohol

    		 Others Inflammation/Immunology
    Prostaglandin F2α alcohol (PGF2α alcohol) is an analog of PGF2α. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist .
    Prostaglandin F2α alcohol
  • HY-137412
    PGF2α 1,15-lactone

    Prostaglandin F2α 1,15-lactone

    		 Others Endocrinology
    PGF2α 1,15-lactone (Prostaglandin F2α 1,15-lactone) is a lipid-soluble internal ester of PGF2α. PGF2α 1,15-lactone decreases menstrual cycle lengths in non-pregnant rhesus monkeys. PGF2α 1,15-lactone terminates early pregnancy in the monkey .
    PGF2α 1,15-lactone
  • HY-W399193
    PGF2α 1,9-lactone

    Prostaglandin F2α 1,9-lactone

    		 Others Metabolic Disease
    PGF2α 1,9-lactone (Prostaglandin F2α 1,9-lactone) is a prostaglandin lactone. PGF2α 1,9-lactone shows resistant to hydrolysis by plasma esterases .
    PGF2α 1,9-lactone
  • HY-106037
    PGF2α-isopropyl ester

    		Others Others
    PGF2α-isopropyl ester is a Prostaglandin F2α (HY-12956) derivative, which is active in lowering the intraocular pressure (IOP) through increased uveoscleral outflow of aqueous humor. PGF2α-isopropyl ester causes side effects of conjunctival hyperemia and ocular irritation .
    PGF2α-isopropyl ester
  • HY-113909
    Dinoprost (methoxyamine)

    Prostaglandin F2α (methoxyamine); PGF2α (methoxyamine)

    		 Prostaglandin Receptor Endogenous Metabolite Autophagy Apoptosis Endocrinology
    Dinoprost methoxyamine is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost methoxyamine is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost methoxyamine plays a key role in the onset and progression of labour [2].
    Dinoprost (methoxyamine)
  • HY-131617
    Prostaglandin F2α 1,11-lactone

    PGF2α 1,11-lactone

    		 Others Others
    Prostaglandin F2α 1,11-lactone is a prostaglandin. Prostaglandin F2α 1,11-lactone is absorbed by the eye. Prostaglandin F2α 1, 11-Lactone has metabolic stability on the corneal surface and conjunctiva. Prostaglandin F2α 1,11-lactone can be used in the treatment of glaucoma .
    Prostaglandin F2α 1,11-lactone
  • HY-12956S1
    Dinoprost-d9

    Prostaglandin F2a-d9; PGF2α-d9

    		 Prostaglandin Receptor Endogenous Metabolite Autophagy Apoptosis Endocrinology
    Dinoprost-d9 is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour[1][2].
    Dinoprost-d9
  • HY-12956S
    Dinoprost-d4

    Prostaglandin F2a-d4; PGF2α-d4

    		 Prostaglandin Receptor Endogenous Metabolite Autophagy Apoptosis Endocrinology
    Dinoprost-d4 is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour[1][2].
    Dinoprost-d4
  • HY-12956S2
    Dinoprost-13C5

    Prostaglandin F2α-13C5; PGF2α-13C5

    		 Prostaglandin Receptor Endogenous Metabolite Autophagy Apoptosis Isotope-Labeled Compounds Endocrinology
    Dinoprost- 13C5 is 13C labeled Dinoprost (HY-12956). Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour [2].
    Dinoprost-13C5
  • HY-158571
    17-Phenoxy trinor prostaglandin F2α

    17-Phenoxy trinor PGF2α

    		 Others Metabolic Disease Inflammation/Immunology
    17-Phenoxy trinor prostaglandin F2α is a PGF2α analog .
    17-Phenoxy trinor prostaglandin F2α
  • HY-125150
    AL-3138

    11-Deoxy-16-fluoro PGF2α

    		 Prostaglandin Receptor Endogenous Metabolite Endocrinology
    AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production .
    AL-3138
  • HY-137544
    16-Phenyl tetranor Prostaglandin F2α

    16-Phenyl tetranor PGF2α

    		 Others Metabolic Disease
    16-phenyl tetranor Prostaglandin F2α (16-phenyl tetranor PGF2α) is a metabolically stable analog of PGF2α. The affinity of 16-phenyl tetranor PGF2α at the FP receptor of ovine luteal cells is poor (8.7%) compared to PGF2α.
    16-Phenyl tetranor Prostaglandin F2α
  • HY-139063
    16-Phenoxy tetranor prostaglandin F2α

    16-Phenoxy tetranor PGF2α

    		 Others Metabolic Disease
    16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.
    16-Phenoxy tetranor prostaglandin F2α
  • HY-114841
    ONO 207

    13,14-Dihydrodinoprost; 13,14-dihydro PGF2α

    		 Prostaglandin Receptor Endocrinology
    13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 μg/100 g.
    ONO 207
  • HY-125774
    Bimatoprost acid

    17-Phenyl trinor PGF2α

    		 Prostaglandin Receptor Others
    Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor .
    Bimatoprost acid
  • HY-158595
    15(R),19(R)-Hydroxy prostaglandin F2α

    15(R),19(R)-Hydroxy PGF2α

    		 Others Others
    15(R),19(R)-Hydroxy prostaglandin F2α (15(R),19(R)-Hydroxy PGF2α) is an analog of 19(R)-Hydroxy-prostaglandin F2α. 19(R)-Hydroxy-prostaglandin F2α (HY-N7857) is an ω-1 hydroxylase metabolite of PGF2α found in human semen .
    15(R),19(R)-Hydroxy prostaglandin F2α
  • HY-116161A
    17-Phenyl trinor PGF2α isopropyl ester

    		Prostaglandin Receptor Endocrinology
    17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.1 The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost.2 This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist.3 In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative is examined for IOP-lowering activity during the development of latanoprost.4 At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester is the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative is also significantly more irritating to the eye than latanoprost.
    17-Phenyl trinor PGF2α isopropyl ester
  • HY-116679
    17-trifluoromethylphenyl trinor Prostaglandin F2α

    17-Trifluoromethylphenyl trinor PGF2α

    		 Prostaglandin Receptor Endocrinology
    A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists.4 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF2α is a potent luteolytic, with a potency equal to or greater than fluprostenol and cloprostenol.
    17-trifluoromethylphenyl trinor Prostaglandin F2α
  • HY-137504
    20-ethyl Prostaglandin F2α

    ICI 74205; 20-ethyl PGF2α

    		 Prostaglandin Receptor Metabolic Disease
    20-ethyl Prostaglandin F2α (20-ethyl PGF2α) is an analog of PGF2α in which the ω-chain has been extended by the addition of two more methylene carbon atoms. It is therefore a modified version of the clinically approved glaucoma medication unoprostone.noprostone also contains lower side chain modifications (13,14-dihydro-15-keto) which severely limit its affinity for FP receptors, contributing to its lack of potency as a medication. 20-ethyl PGF2α retains the natural 15(S) allylic hydroxyl in the lower side chain, which may improve its potency as an intraocular hypotensive agent compared to unoprostone. The 2 carbon extension in 20-ethyl-PGF2α increases the Ki (120 nM) for the FP receptor from bovine corpus luteum only about 2.5-fold compared to PGF2α (50 nM).2 In vivo effects may be prolonged using 20-ethyl PGF2α, as the activity of 15-hydroxy PGDH using 20-ethyl PGF2α as a substrate is only 35% of the activity observed with PGF2α.
    20-ethyl Prostaglandin F2α
  • HY-128550
    Carboprost methyl

    Methyl carboprost; 15(S)-15-Methyl PGF2α methyl ester; U-36384

    		 Prostaglandin Receptor Endocrinology
    15(S)-15-methyl Prostaglandin F2α methyl ester (15(S)-15-methyl PGF2α methyl ester) is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability. Hydrolysis of the methyl ester in vivo releases the biologically active 15(S)-15-methyl PGF2α, which is a potent uterine stimulant and abortifacient.
    Carboprost methyl
  • HY-W746888
    17-Phenyl trinor prostaglandin F2α diethyl amide

    17-p-PGF2α-NEt2; 17-Phenyl trinor PGF2α diethyl amide

    		 Prostaglandin Receptor Cardiovascular Disease
    17-Phenyl trinor prostaglandin F2α diethyl amide (17-phenyl trinor PGF2α diethyl amide) is a PGF2α analog with hypotensive efficacy .
    17-Phenyl trinor prostaglandin F2α diethyl amide
  • HY-N7857
    19(R)-Hydroxy-prostaglandin F2α

    19(R)-Hydroxy PGF2α

    		 Others Metabolic Disease
    19(R)-Hydroxy-prostaglandin F2α (19(R)-hydroxy PGF2α) is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-Hydroxy-PGFs compounds (F2α and F1α together) in fresh human semen is about 20 μg/mL. 19(R)-Hydroxy-prostaglandin F2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM.
    19(R)-Hydroxy-prostaglandin F2α
  • HY-114867
    (15R)-Bimatoprost

    15(R)-17-phenyl trinor PGF2α ethyl amide

    		 Others Endocrinology
    (15R)-Bimatoprost (15(R)-17-phenyl trinor PGF2α ethyl amide) is a prostaglandin analog used to treat glaucoma and ocular hypertension. (15R)-Bimatoprost is an isomer of Bimatoprost with an inverted (β) hydroxyl group on C-15 .
    (15R)-Bimatoprost
  • HY-113778
    15-keto-17-phenyl trinor Prostaglandin F2α

    15-keto-17-phenyl trinor PGF2α

    		 Prostaglandin Receptor Endocrinology
    Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.1 Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trinor PGF2α. 15-keto-17-phenyl trinor PGF2α is a potential metabolite of bimatoprost when administered to animals. 15-keto PG analogs are potential minor impurities in commercial preparations of their corresponding bulk drug compounds. Although much less potent that the parent compound, 15-keto PGs still retain the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye.2 15-keto Latanoprost (15-keto-17-phenyl-13,14-dihydro trinor PGF2α isopropyl ester) is a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type PGs; for example, PGF2α will produce this degree of miosis at a dose of less than 1 μg/eye.
    15-keto-17-phenyl trinor Prostaglandin F2α
  • HY-139121
    15(R)-17-Phenyl trinor Prostaglandin F2α

    15-epi Bimatoprost free acid; 15(R)-Bimatoprost free acid; 15(R)-17-phenyl trinor PGF2α

    		 Prostaglandin Receptor Endocrinology
    17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive agent. Investigations in our lab have shown that 17-phenyl trinor PGF2α ethyl amide is converted by an amidase enzymatic activity in the human cornea to yield the corresponding free acid, with a conversion rate of about 25 μg/cornea/24 hr. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist. 15(R)-17-phenyl trinor PGF2α is the 15-epi, or “unnatural” isomer of this active free acid metabolite. It has much diminished FP receptor-mediated activity, which is generally 1.5 to 2 logs less than the 15(S)-isomer. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.
    15(R)-17-Phenyl trinor Prostaglandin F2α
  • HY-139124
    15(R)-15-Methyl Prostaglandin F2α

    15(R)-Carboprost; 15(R)-15-methyl PGF2α

    		 Others Metabolic Disease
    15(R)-15-Methyl Prostaglandin F2α (15(R)-Carboprost; 15(R)-15-methyl PGF2α) is a metabolically stable analog of PGF2α. 15(R)-15-Methyl Prostaglandin F2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-Methyl Prostaglandin F2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.
    15(R)-15-Methyl Prostaglandin F2α
  • HY-137547
    20-Hydroxy-PGF2α

    		Prostaglandin Receptor Metabolic Disease
    20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
    20-Hydroxy-PGF2α
  • HY-125626
    8-iso-15-keto Prostaglandin F2α

    8-iso-15-keto PGF2α

    		 Prostaglandin Receptor Cardiovascular Disease
    8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a partial agonist for Thromboxane receptor (TP), which exhibits a vasoconstrictor efficacy with a pD2 of 5.8. 8-iso-15-keto Prostaglandin F2α mediates a weak relaxation of rats aorta rings at high concentration .
    8-iso-15-keto Prostaglandin F2α
  • HY-124219
    17-Phenoxy trinor prostaglandin F2α ethyl amide

    17-Phenoxy trinor PGF2α ethyl amide

    		 Prostaglandin Receptor Others
    17-Phenoxy trinor prostaglandin F2α ethyl amide (17-Phenoxy trinor PGF2α ethyl amide) is an analog of Bimatoprost (HY-12956). 17-Phenoxy trinor prostaglandin F2α ethyl amide is an agonist for Prostaglandin F2α Receptor (FP receptor). 17-Phenoxy trinor prostaglandin F2α ethyl amide is potent to reduce the intraocular pressure and attenuate the glaucoma [2].
    17-Phenoxy trinor prostaglandin F2α ethyl amide
  • HY-116051
    16,16-Dimethylprostaglandin F2α

    16,16-Dimethyl-PGF2α

    		 Others Cardiovascular Disease
    16,16-Dimethylprostaglandin F2α (16,16-Dimethyl-PGF2α) is a potent analog of PGF2α (HY-12956), which exhibits similar binding potency as PGF2α does. 16,16-Dimethylprostaglandin F2α serves as a bronchoconstrictor [2].
    16,16-Dimethylprostaglandin F2α
  • HY-149502
    8-Iso-15(R)-prostaglandin F2α

    8-Iso(15R)PGF2α; 15(R)-8-Iso-PGF2α

    		 Prostaglandin Receptor Metabolic Disease
    8-Iso-15(R)-prostaglandin F2α (8-Iso(15R)PGF2α), a type of eicosanoid, is a oxidized metabolite of Prostaglandin F2α (PGF2α) .
    8-Iso-15(R)-prostaglandin F2α
  • HY-129397
    2,3-Dinor-11beta-prostaglandin F2alpha

    BPG; 2,3-Dinor-11β-PGF2α; 2,3-dinor-11-epi PGF2α

    		 Prostaglandin Receptor Endocrinology
    2,3-Dinor-11beta-prostaglandin F2alpha (2,3-Dinor-11β-PGF2α) is a metabolite of PGD2. Urinary excretion of 2,3-Dinor-11beta-prostaglandin F2alpha is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-Dinor-11beta-prostaglandin F2alpha levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.
    2,3-Dinor-11beta-prostaglandin F2alpha
  • HY-132277
    15-Keto Bimatoprost

    		Others Endocrinology
    15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive .
    15-Keto Bimatoprost
  • HY-125774S
    Bimatoprost acid-d4

    17-Phenyl trinor PGF2α-d4

    		 Isotope-Labeled Compounds Others
    Bimatoprost acid-d4 (17-Phenyl trinor PGF2α-d4) is the deuterium labeled Bimatoprost acid[1].
    Bimatoprost acid-d4
  • HY-131632
    1a,1b-Dihomo prostaglandin F2α

    1a,1b-Dihomo-PGF2α

    		 Endogenous Metabolite Others
    1a,1b-Dihomo prostaglandin F2α (1a,1b-Dihomo-PGF2α) is the derivative of Prostaglandin F2α (HY-12956) .
    1a,1b-Dihomo prostaglandin F2α
  • HY-113246
    15-keto-Prostaglandin F2a

    15-keto-PGF2α

    		 Prostaglandin Receptor Endogenous Metabolite Endocrinology
    15-keto-Prostaglandin F2α (15-keto-PGF2α) is a metabolite of Prostaglandin F2α. Prostaglandin F2α. Prostaglandin F2α is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist and plays a key role in the onset and progression of labour .
    15-keto-Prostaglandin F2a
  • HY-113208
    13,14-Dihydro-15-keto Prostaglandin F2α

    13,14-Dihydro-15-keto-PGF2α

    		 Endogenous Metabolite Others
    13,14-Dihydro-15-keto Prostaglandin F2α (13,14-Dihydro-15-keto-PGF2α) is an endogenous metabolite present in Blood that can be used for the research of Pregnancy [2].
    13,14-Dihydro-15-keto Prostaglandin F2α
  • HY-111478
    Tiaprost

    Iliren

    		 Prostaglandin Receptor Metabolic Disease Endocrinology
    Tiaprost is a prostaglandin F2α (PGF2α) analogue.
    Tiaprost
  • HY-149588
    17-Trifluoromethylphenyl trinor prostaglandin F2α methyl ester

    		Others Endocrinology
    17-Trifluoromethylphenyl trinor prostaglandin F2α methyl ester is an analog of PGF2α .
    17-Trifluoromethylphenyl trinor prostaglandin F2α methyl ester
  • HY-116161
    Bimatoprost isopropyl ester

    		Others Cardiovascular Disease Others
    15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
    Bimatoprost isopropyl ester
  • HY-107381
    (+)-Cloprostenol

    D-Cloprostenol

    		 Prostaglandin Receptor Endocrinology
    (+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.
    (+)-Cloprostenol
  • HY-107381A
    (+)-Cloprostenol sodium

    D-Cloprostenol sodium

    		 Prostaglandin Receptor Endocrinology
    (+)-Cloprostenol sodium is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.
    (+)-Cloprostenol sodium
  • HY-118816
    11β-Prostaglandin F2α

    11-epi PGF2α-EA; 11β-PGF2α-EA; 11β-Prostamide F2α

    		 Others Metabolic Disease
    11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.
    11β-Prostaglandin F2α
  • HY-131729
    16-Phenoxy tetranor Prostaglandin A2

    		Others Cardiovascular Disease
    16-Phenoxy tetranor Prostaglandin A2 is a metabolite of uprostone and an analog of the antifertility hormone PGF2α .
    16-Phenoxy tetranor Prostaglandin A2
  • HY-108415
    Cloprostenol sodium salt

    ICI 80996 sodium salt

    		 Prostaglandin Receptor Endocrinology
    Cloprostenol sodium salt (ICI 80996 sodium salt) is a potent synthetic prostaglandin analogue, acts as a luteolytic agent , and is a PGF2α receptor agonist [2].
    Cloprostenol sodium salt
  • HY-N12119
    ent-Prostaglandin F2α

    		Endogenous Metabolite Others
    ent-Prostaglandin F2α is the opposite enantiomer of PGF2α. ent-Prostaglandin F2α can be found in urine .
    ent-Prostaglandin F2α
  • HY-124175
    16-Phenoxy prostaglandin F2α ethyl amide

    		Others Endocrinology
    16-Phenoxy prostaglandin F2α ethyl amide is a metabolically stable PGF2α analogue containing a acetamide structure .
    16-Phenoxy prostaglandin F2α ethyl amide

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