1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. Bimatoprost acid

Bimatoprost acid  (Synonyms: 17-Phenyl trinor PGF2α)

Cat. No.: HY-125774
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Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor.

For research use only. We do not sell to patients.

Bimatoprost acid Chemical Structure

Bimatoprost acid Chemical Structure

CAS No. : 38344-08-0

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Description

Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor[1].

Cellular Effect
Cell Line Type Value Description References
CHO EC50
> 10000 nM
Compound: 1
Agonist activity at human IP receptor expressed in CHO cells assessed as increase in intracellular cAMP level by HTRF method
Agonist activity at human IP receptor expressed in CHO cells assessed as increase in intracellular cAMP level by HTRF method
[PMID: 28105284]
CHO EC50
12 nM
Compound: 1
Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay
Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay
[PMID: 28105284]
CHO EC50
8600 nM
Compound: 1
Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay
Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay
[PMID: 28105284]
Molecular Weight

388.50

Formula

C23H32O5

CAS No.
SMILES

O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Bimatoprost acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Bimatoprost acid
Cat. No.:
HY-125774
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