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T‐HCA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Endogenous Metabolite (1) Isotope-Labeled Compounds (1)
By Research Areas:	Neurological Disease (1)
Oligonucleotides:	Cholesterol (1)

3

Inhibitors & Agonists

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

(E)-4-Hydroxycrotonic acid trans-4-Hydroxycrotonic acid; trans-γ-Hydroxycrotonic acid; T‐HCA	Others	Neurological Disease
(E)-4-Hydroxycrotonic acid (T-HCA) is a high-affinity ligand for GHB binding sites, with a k_i value of 1.1 μM. The introduction of diaryl substituents into (E)-4-Hydroxycrotonic acid significantly enhances its affinity for GHB binding sites, with k_i values ranging from 0.023 to 0.075 μM. (E)-4-Hydroxycrotonic acid holds promise for optimizing GHB ligand structures and assisting in the development of effective three-dimensional pharmacophore models .

Taurohyocholic acid sodium salt THCA sodium salt	Endogenous Metabolite	Others
Taurohyocholic acid sodium salt is a metabolite that can be extracted from Pig gallbladder bile .

Taurohyocholic acid-d4 sodium THCA-d₄ sodium	Isotope-Labeled Compounds	Others
Taurohyocholic acid-d₄ (sodium) is the deuterium labeled Taurohyocholic acid sodium[1].

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