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Results for "

AMCA,SE

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Fluorescent Dye

2

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P2797A
    Chitinase, Streptomyces griseus

    AMCase, Streptomyces griseus

    		 Endogenous Metabolite Others
    Chitinase, Streptomyces griseus is a chitinase mainly found in Bacillus species and uses colloidal chitin as a substrate. The Km and Vmax of Chitinase are 4.28 mg/mL and 14.29 μg/(Min·mL) respectively. The final enzymatic hydrolysis product is N-acetylglucosamine, and the monomer and dimer contents are 14.33% and 85.67% respectively .
    Chitinase, Streptomyces griseus
  • HY-P2797
    Chitinase, Serratia marcescens

    AMCase, Serratia marcescens

    		 Bacterial Metabolic Disease Inflammation/Immunology
    Chitinase, Serratia marcescens (EC 3.2.1.14) has partial lysozyme activity and is widely found in bacteria, fungi, animals and some plants. Chitinase belongs to the glycosyl hydrolase family. Chitinase catalyzes chito-oligosaccharide hydrolysis. Chitinases also can serve as prognostic biomarkers of disease progression. Chitinase can be used in the research of pathogenesis of various human fibrotic and inflammatory disorders, particularly those of the lung (idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, sarcoidosis, and asthma) and the gastrointestinal tract (inflammatory bowel diseases (IBDs) and colon cancer) .
    Chitinase, Serratia marcescens
  • HY-115661
    Bisdionin C

    		Bacterial Infection
    Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively .
    Bisdionin C
  • HY-D0026
    AMCA,SE

    7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

    		 Fluorescent Dye Others
    7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester is a bioReagent, suitable for fluorescence, can be used for amine-reactive labeling.
    AMCA,SE
  • HY-125279
    OAT-2068

    		Others Inflammation/Immunology
    OAT-2068 is a selective, high activity and orally active inhibitor of mouse chitotriosidase (mCHIT1) (IC50=29 nM) and displays 143-fold selectivity over m AMCase (IC50=4170 nM). OAT-2068 displays a good pharmacokinetic profile and is an ideal tool to study the role of CHIT1 in biological systems, including animal models of human diseases .
    OAT-2068

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