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Clomipramine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Dopamine Receptor (2) Drug Metabolite (4) Isotope-Labeled Compounds (1) Serotonin Transporter (8)
By Research Areas:	Neurological Disease (13)

13

Inhibitors & Agonists

1

Natural
Products

5

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Clomipramine* 2 Publications Verification Chlorimipramine; G-34586; NSC-169865	Serotonin Transporter	Neurological Disease
Clomipramine (Chlorimipramine) is a potent 5-HT reuptake blocker with the IC₅₀ value of 1.5 nM. Clomipramine is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .

Clomipramine hydrochloride 2 Publications Verification Chlorimipramine hydrochloride; G-34586 hydrochloride; NSC-169865 hydrochloride	Serotonin Transporter	Neurological Disease
Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC₅₀ value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .

Clomipramine-d3 hydrochloride Chlorimipramine-d₃ (hydrochloride); G-34586-d₃ (hydrochloride); NSC-169865-d₃ (hydrochloride)	Serotonin Transporter Dopamine Receptor	Neurological Disease
Clomipramine-d₃ (hydrochloride) is a deuterium labeled Clomipramine hydrochloride. Clomipramine hydrochloride is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].

*N-Desmethyl clomipramine* hydrochloride** DesmethylClomipramine hydrochloride; NorClomipramine hydrochloride	Drug Metabolite	Neurological Disease
N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine. Clomipramine is a tricyclic antidepressant .

Clomipramine (Standard)	Serotonin Transporter	Neurological Disease
Clomipramine (Standard) is the analytical standard of Clomipramine. This product is intended for research and analytical applications. Clomipramine (Chlorimipramine) is a potent 5-HT reuptake blocker with the IC₅₀ value of 1.5 nM. Clomipramine is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .

Clomipramine hydrochloride (Standard)	Serotonin Transporter	Neurological Disease
Clomipramine (hydrochloride) (Standard) is the analytical standard of Clomipramine (hydrochloride). This product is intended for research and analytical applications. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC₅₀ value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD) .

Clomipramine-d3 Chlorimipramine-d₃; G-34586-d₃; NSC-169865-d₃	Serotonin Transporter Dopamine Receptor	Neurological Disease
Clomipramine-d₃ is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].

Clomipramine-d6 hydrochloride Chlorimipramine-d₆ (hydrochloride); G-34586-d₆ (hydrochloride); NSC-169865-d₆ (hydrochloride)	Serotonin Transporter	Neurological Disease
Clomipramine-d₆ (hydrochloride) is the deuterium labeled Clomipramine hydrochloride. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

Clomipramine-13C,d3 hydrochloride Chlorimipramine-¹³C,d₃ hydrochloride; G-34586-¹³C,d₃ hydrochloride; NSC-169865-¹³C,d₃ hydrochloride	Isotope-Labeled Compounds Serotonin Transporter	Neurological Disease
Clomipramine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Clomipramine (hydrochloride). Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

N-Desmethyl clomipramine DesmethylClomipramine; NorClomipramine	Drug Metabolite	Neurological Disease
Desmethylclomipramine (Norclomipramine) is a metabolite of *Clomipramine* (HY-B0457A) and can be used for neurological research .

*N-Desmethyl clomipramine-d3 hydrochloride* DesmethylClomipramine-d₃ (hydrochloride)；NorClomipramine-d₃ hydrochloride	Drug Metabolite	Neurological Disease
N-Desmethyl Clomipramine-d₃ (hydrochloride) is the deuterium labeled N-Desmethyl Clomipramine. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine[1]

*N-Desmethyl clomipramine* hydrochloride (Standard)** DesmethylClomipramine hydrochloride (Standard); NorClomipramine hydrochloride (Standard)	Drug Metabolite	Neurological Disease
N-Desmethyl Clomipramine (hydrochloride) (Standard) is the analytical standard of N-Desmethyl Clomipramine (hydrochloride). This product is intended for research and analytical applications. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine. Clomipramine is a tricyclic antidepressant .

Capeserod SL65.0155 free base	5-HT Receptor	Neurological Disease
Capeserod (SL65.0155 free base) is an agonist for serotonin receptor (5-HT receptor), with a K_i of 0.6 nM for 5-HT₄ receptor. Capeserod enhances expression of phopshorilated cAMP-response element binding protein (p-CREB), vascular endothelium growth factor (VEGF), brain-derived neurotrophic factor (BDNF) and B cell lymphoma-2 (Bcl-2) proteins in hippocampus, and exhibits antidepressant-like efficacy in Wistar rats models .

Cat. No.	Product Name	Category	Target	Chemical Structure

N-Desmethyl clomipramine DesmethylClomipramine; NorClomipramine	Structural Classification Natural Products Source classification Endogenous metabolite	Drug Metabolite
Desmethylclomipramine (Norclomipramine) is a metabolite of *Clomipramine* (HY-B0457A) and can be used for neurological research .

Cat. No.	Product Name	Chemical Structure

Clomipramine-d3 hydrochloride
Clomipramine-d₃ (hydrochloride) is a deuterium labeled Clomipramine hydrochloride. Clomipramine hydrochloride is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].

*N-Desmethyl clomipramine-d3 hydrochloride*
N-Desmethyl Clomipramine-d₃ (hydrochloride) is the deuterium labeled N-Desmethyl Clomipramine. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine[1]

Clomipramine-d3
Clomipramine-d₃ is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].

Clomipramine-d6 hydrochloride
Clomipramine-d₆ (hydrochloride) is the deuterium labeled Clomipramine hydrochloride. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

Clomipramine-13C,d3 hydrochloride
Clomipramine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Clomipramine (hydrochloride). Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

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