2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. N-Desmethyl clomipramine-d3 hydrochloride

N-Desmethyl clomipramine-d3 hydrochloride  (Synonyms: Desmethylclomipramine-d3 (hydrochloride)；Norclomipramine-d3 hydrochloride)

Cat. No.: HY-12388AS Purity: 99.81%
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N-Desmethyl Clomipramine-d3 (hydrochloride) is the deuterium labeled N-Desmethyl Clomipramine. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine[1]

For research use only. We do not sell to patients.

N-Desmethyl clomipramine-d<sub>3</sub> hydrochloride Chemical Structure

N-Desmethyl clomipramine-d3 hydrochloride Chemical Structure

CAS No. : 1189971-04-7

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500 μg USD 210 In-stock
1 mg USD 340 In-stock
5 mg USD 850 In-stock
10 mg USD 1400 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

N-Desmethyl Clomipramine-d3 (hydrochloride) is the deuterium labeled N-Desmethyl Clomipramine. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine[1]

Molecular Weight

340.31

Formula

C18H19D3Cl2N2
CAS No.
Unlabeled CAS

29854-14-6
Appearance

Solid

Color

Off-white to light yellow

SMILES

ClC1=CC2=C(C=C1)CCC3=C(C=CC=C3)N2CCCNC([2H])([2H])[2H].[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (73.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 25 mg/mL (73.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9385 mL 14.6925 mL 29.3850 mL
5 mM 0.5877 mL 2.9385 mL 5.8770 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.9385 mL 14.6925 mL 29.3850 mL 73.4624 mL
5 mM 0.5877 mL 2.9385 mL 5.8770 mL 14.6925 mL
10 mM 0.2938 mL 1.4692 mL 2.9385 mL 7.3462 mL
15 mM 0.1959 mL 0.9795 mL 1.9590 mL 4.8975 mL
20 mM 0.1469 mL 0.7346 mL 1.4692 mL 3.6731 mL
25 mM 0.1175 mL 0.5877 mL 1.1754 mL 2.9385 mL
30 mM 0.0979 mL 0.4897 mL 0.9795 mL 2.4487 mL
40 mM 0.0735 mL 0.3673 mL 0.7346 mL 1.8366 mL
50 mM 0.0588 mL 0.2938 mL 0.5877 mL 1.4692 mL
60 mM 0.0490 mL 0.2449 mL 0.4897 mL 1.2244 mL
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N-Desmethyl clomipramine-d3 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Desmethyl clomipramine-d31189971-04-7Desmethylclomipramine-d3 (hydrochloride)；Norclomipramine-d3Drug MetaboliteplasmaN-desmethylmetaboliteClomipraminetricyclicantidepressantInhibitorinhibitorinhibit

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