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FKBP52

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Calcium Channel (1) FKBP (3) HSP (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (1) Neurological Disease (3)

3

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

ILS-920	FKBP Calcium Channel	Neurological Disease Inflammation/Immunology
ILS-920 is a nonimmunosuppressive Rapamycin analog with reduced immunosuppressive activity and potent neuroprotective activity. ILS-920 binds selectively to the immunophilin *FKBP52* and to the β1-subunit of L-type voltage-gated calcium channels (VGCC). ILS-920 shows 200-fold selectivity for *FKBP52* versus FKBP12 .

FKBP51-Hsp90-IN-2	FKBP HSP	Neurological Disease Cancer
FKBP51-Hsp90-IN-2 (Compound E08) is a selective *FKBP51-Hsp90* protein-protein interaction inhibitor with IC₅₀ values of 0.4 µM and 5 µM for *FKBP51* and *FKBP52, respectively. FKBP51-Hsp90-IN-2 also effectively stimulates cellular energy metabolism and neurite growth. FKBP*51-Hsp90-IN-2 can be used in research on neurodegenerative diseases and cancer .

FKBP51F67V-selective antagonist Ligand2	FKBP	Neurological Disease
FKBP51F67V-selective antagonist Ligand2 (example 3-3) is a potent FKBP51 F67V-selective antagonist ligand. FKBP51F67V-selective antagonist Ligand2 reverses the anxiogenic phenotype induced by overexpression of FKBP51 F67V in the amygdala. FKBP51F67V-selective antagonist Ligand2 binds to FKBP51 F67V, but not to wild-type FKBP51 or FKBP52 .

Cat. No.	Compare	Product Name	Species	Source

	FKBP4 Protein, Human (His) rHuPeptidyl-prolyl cis-trans isomerase FKBP4/FKBP4, His; Peptidyl-prolyl cis-trans isomerase FKBP4; 51kDa FK506-binding protein; 51kDa FK506-binding protein; 59kDa immunophilin; FK506-binding protein 4; FKBP59; HSP-binding immunophilin; immunophilin FKBP52; Rotamase; FKBP4	Human	E. coli
	The FKBP4 protein is an immunophilin with peptidyl prolyl cis-trans isomerase (PPIase) and co-chaperone activity. It plays a key role in the formation of hybrids with steroid receptors, specifically by interacting with heat shock protein 90 (HSP90). FKBP4 Protein, Human (His) is the recombinant human-derived FKBP4 protein, expressed by E. coli , with C-6*His labeled tag. The total length of FKBP4 Protein, Human (His) is 459 a.a., with molecular weight of 50-60 kDa.

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	FKBP52 Antibody	WB, ICC/IF, IHC-P, FC	Human, Mouse
	FKBP52 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 52 kDa, targeting to FKBP52. It can be used for WB,ICC,IHC-P,FC assays with tag free, in the background of Human, Mouse.

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