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Gastric ulcer model

" in MedChemExpress (MCE) Product Catalog:

9

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Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0310

    Histamine Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach?and?intestines ulcers. Nizatidine works by decreasing the secretion of gastric?acid the stomach makes and prevent ulcers from coming back after they have healed in animal models .
    Nizatidine
  • HY-B2181

    Bismuth(III) oxynitrate

    Bacterial Infection Metabolic Disease Inflammation/Immunology
    Bismuth subnitrate (Bismuth(III) oxynitrate) is a simple and efficient catalyst for the synthesis of methyl ketone by martensitic acetylene hydration reaction. When Bismuth subnitrate is intraperitoneally injected into mice, the distribution characteristics of bismuth (Bi) in the brain are similar to those of other exogenous metals such as mercury, silver and gold. Bismuth subnitrate has antibacterial activity, which can inhibit the growth of Staphylococcus aureus and Escherichia coli. Bismuth subnitrate is effective orally and can be used for the study of gastrointestinal diseases, which has protective effect on alcoholic gastric ulcer in rats .
    Bismuth subnitrate
  • HY-N7140
    Gamma-Linolenic acid
    3 Publications Verification

    γ-Linolenic acid

    Endogenous Metabolite Apoptosis NF-κB ERK JNK Neurological Disease Inflammation/Immunology Cancer
    Gamma-linolenic acid (γ-Linolenic acid) is an orally active unsaturated fatty acid. Gamma-linolenic acid exerts anti-inflammatory effects by inhibiting the NF-κB pathway and the phosphorylation of ERK1/2 and JNK. At the same time, it exerts anticancer effects by inducing apoptosis (Apoptosis) in cancer cells. Additionally, Gamma-linolenic acid also has antioxidant and memory-improving effects. It holds promise for research in the fields of inflammation, neurology, and cancer diseases .
    Gamma-Linolenic acid
  • HY-B0954A

    mAChR Endocrinology
    Oxyphencyclimine is an orally active muscarinic receptor (mAChR) antagonist. Oxyphencyclimine is effective in reducing ulceration index and increasing pepsin activity in rat gastric ulcer model. Oxyphencyclimine can be used in studies of peptic ulcer disease and gastrointestinal spasm .
    Oxyphencyclimine
  • HY-B0310R

    Histamine Receptor Inflammation/Immunology Endocrinology Cancer
    Nizatidine (Standard) is the analytical standard of Nizatidine. This product is intended for research and analytical applications. Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models .
    Nizatidine (Standard)
  • HY-B0377G

    MK-208 (GMP)

    Histamine Receptor Inflammation/Immunology Cancer
    Famotidine GMP (MK-208 GMP) is Famotidine (HY-B0377) produced in GMP guideline. Famotidine GMP is a competitive histamine H2-receptor antagonist, inhibits gastric secretion, activates the gastric mucosal defensive mechanisms. Famotidine GMP ameliorates peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD/GORD) in rats model .
    Famotidine (GMP)
  • HY-129641

    Others Others
    KF-392 is an orally active antiulcer agent .
    KF-392
  • HY-134521

    COX Inflammation/Immunology
    Diclofenac amide is a prodrug for Diclofenac sodium (HY-15037). Diclofenac amide is an orally active inhibitor for COX-1/2, that inhibits the production of prostaglandins (PG) and thromboxanes (TX). Diclofenac amide exhibits anti-inflammatory efficacy in Carrageenan (HY-125474)-induced rat paw edema model without causing gastric ulcer (300 μmol/kg) .
    Diclofenac amide
  • HY-116208

    KU-1257

    Histamine Receptor Inflammation/Immunology
    Dalcotidine (KU-1257) is an orally active and competitive histamine H2 receptor antagonist. Dalcotidine promotes the healing of chronic ulcers and inhibits gastric acid secretion .
    Dalcotidine

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