2. Immunology/Inflammation
  3. COX
  4. Diclofenac amide

Diclofenac amide is a prodrug for Diclofenac sodium (HY-15037). Diclofenac amide is an orally active inhibitor for COX-1/2, that inhibits the production of prostaglandins (PG) and thromboxanes (TX). Diclofenac amide exhibits anti-inflammatory efficacy in Carrageenan (HY-125474)-induced rat paw edema model without causing gastric ulcer (300 μmol/kg).

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Diclofenac amide Chemical Structure

Diclofenac amide Chemical Structure

CAS No. : 15362-40-0

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Diclofenac amide Related Antibodies

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Description

Diclofenac amide is a prodrug for Diclofenac sodium (HY-15037). Diclofenac amide is an orally active inhibitor for COX-1/2, that inhibits the production of prostaglandins (PG) and thromboxanes (TX). Diclofenac amide exhibits anti-inflammatory efficacy in Carrageenan (HY-125474)-induced rat paw edema model without causing gastric ulcer (300 μmol/kg)[1].

Molecular Weight

278.14

Formula

C14H9Cl2NO
CAS No.
Appearance

Solid

SMILES

O=C1N(C2=C(Cl)C=CC=C2Cl)C3=C(C=CC=C3)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Diclofenac amide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Diclofenac amide15362-40-0COXCyclooxygenasegastric ulcerorally activeWistar ratSwiss mouseInhibitorinhibitorinhibit

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