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Results for "

Granzyme B Inhibitor

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

4

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P10149
    Ac-IEPD-CHO

    		Caspase Cancer
    Ac-IEPD-CHO is a reversible granzyme B inhibitor with a Ki of 80 nM . Ac-IEPD-CHO is also a caspase-8 inhibitor .
    Ac-IEPD-CHO
  • HY-P10004
    Z-Ala-Ala-Asp-CMK

    Z-AAD-CMK

    		 Caspase Inflammation/Immunology
    Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor .
    Z-Ala-Ala-Asp-CMK
  • HY-101297
    Z-IETD-FMK
    45+ Cited Publications

    Z-IE(OMe)TD(OMe)-FMK

    		 Caspase Cancer
    Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective and cell permeable caspase-8 inhibitor . Z-IETD-FMK is also a granzyme B inhibitor .
    Z-IETD-FMK
  • HY-33299
    Serpin B9-IN-1

    BTCA

    		 Biochemical Assay Reagents Cancer
    Serpin B9-IN-1 (BTCA) is an inhibitor that specifically targets Serpin B9 (SB9); SB9 is a natural inhibitor of granzyme B (GrB) , but may promote the metastasis of lung cancer cells into the bone marrow. SB9-overexpressing cancer cells promote proliferation and metastasis in an immune cell-dependent manner by binding to GrB. Inhibition of SB9 by Serpin B9-IN-1 significantly inhibits immunotherapy of lung cancer bone metastases in the caudal artery (CA) mouse model (LCBM) .
    Serpin B9-IN-1
  • HY-113963
    Ac-​IETD-​CHO

    		Apoptosis Cancer
    Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death .
    Ac-​IETD-​CHO

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