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Isoforms Recommended:	Kinesin-14

Results for "

HSET

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Kinesin (4)
By Research Areas:	Cancer (4)

4

Inhibitors & Agonists

1

Natural
Products

2

Recombinant Proteins

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

CW-069 1 Publications Verification	Kinesin	Cancer
CW-069 is an allosteric inhibitor of microtubule motor protein HSET with an IC₅₀ of 75 μM.

AZ82 2 Publications Verification	Kinesin	Cancer
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor, with a K_i of 43 nM and an IC₅₀ of 300 nM for KIFC1.

Solidagonic acid	Kinesin	Cancer
Solidagonic acid inhibits *HSET* motor activity by promoting the conversion from abnormal monopolar to bipolar spindles. Solidagonic acid suppresses fission yeast cell death and enables reversion of the mitotic spindles from a monopolar to bipolar morphology. Solidagonic acid showed the growth inhibitory activity on the seedlings of Lactuca sativa L. and Lolium multiflorum Lam .

Kolavenic acid analog KAA	Kinesin	Cancer
Kolavenic acid analog (KAA) is an anticancer agent. Kolavenic acid analog shows strong activity against *HSET*-overproducing yeast cells. Kolavenic acid analog inhibits centrosome clustering in human cancer cells containing high HSET levels and supernumerary centrosomes .

Cat. No.	Product Name	Category	Target	Chemical Structure

Solidagonic acid	Structural Classification Terpenoids Source classification Diterpenoids Plants Compositae Petalostemun purpureum	Kinesin
Solidagonic acid inhibits *HSET* motor activity by promoting the conversion from abnormal monopolar to bipolar spindles. Solidagonic acid suppresses fission yeast cell death and enables reversion of the mitotic spindles from a monopolar to bipolar morphology. Solidagonic acid showed the growth inhibitory activity on the seedlings of Lactuca sativa L. and Lolium multiflorum Lam .

Species:	Human (2)
Tag:	His (1) Tag Free (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

	KIFC1 Protein, Human KIFC1; Kinesin-like protein KIFC1; Kinesin-like protein 2; Kinesin-related protein HSET	Human	E. coli
	KIFC1 Protein, a minus end-directed microtubule-dependent motor, is crucial for bipolar spindle formation. It also participates in early endocytic vesicle movement, indicating a role in intracellular transport. Additionally, KIFC1 regulates cilium formation and structure, interacting with NUBP1, NUBP2, and PPP1R42, suggesting potential involvement in processes related to nucleotide binding and protein dephosphorylation. KIFC1 Protein, Human is the recombinant human-derived KIFC1 protein, expressed by E. coli , with tag free. The total length of KIFC1 Protein, Human is 369 a.a., .

	KIFC1 Protein, Human (His) KIFC1; Kinesin-like protein KIFC1; Kinesin-like protein 2; Kinesin-related protein HSET	Human	E. coli
	KIFC1 Protein, a minus end-directed microtubule-dependent motor, is crucial for bipolar spindle formation. It also participates in early endocytic vesicle movement, indicating a role in intracellular transport. Additionally, KIFC1 regulates cilium formation and structure, interacting with NUBP1, NUBP2, and PPP1R42, suggesting potential involvement in processes related to nucleotide binding and protein dephosphorylation. KIFC1 Protein, Human (His) is the recombinant human-derived KIFC1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of KIFC1 Protein, Human (His) is 369 a.a., .

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	KIFC1 Antibody (YA3142) HSET; KNSL2	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse
	KIFC1 Antibody (YA3142) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3142), targeting KIFC1, with a predicted molecular weight of 74 kDa (observed band size: 74 kDa). KIFC1 Antibody (YA3142) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.

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