KIFC1 Protein, Human

KIFC1 Protein, a minus end-directed microtubule-dependent motor, is crucial for bipolar spindle formation. It also participates in early endocytic vesicle movement, indicating a role in intracellular transport. Additionally, KIFC1 regulates cilium formation and structure, interacting with NUBP1, NUBP2, and PPP1R42, suggesting potential involvement in processes related to nucleotide binding and protein dephosphorylation. KIFC1 Protein, Human is the recombinant human-derived KIFC1 protein, expressed by E. coli , with tag free. The total length of KIFC1 Protein, Human is 369 a.a., .

KIFC1 protein, a minus end-directed microtubule-dependent motor, plays a crucial role in bipolar spindle formation, as evidenced by its requirement in this process. Additionally, it is implicated in the movement of early endocytic vesicles, suggesting a potential role in intracellular transport. Furthermore, KIFC1 is involved in the regulation of cilium formation and structure. It interacts with NUBP1 and NUBP2, indicating possible associations with cellular processes related to nucleotide binding. Moreover, its interaction with PPP1R42 suggests involvement in regulatory pathways associated with protein dephosphorylation.

Human

E. coli

Tag Free

Q9BW19 (Q305-K673)

3833

QELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANRK

39.8 KDa as predicted

Greater than 90% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.22 μm filtered solution of 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol, 1 mM DTT.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.