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Iridoid Glycoside

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Cytochrome P450 (2) ERK (2) HBV (3) HCV (2) Interleukin Related (1) NF-κB (3) Parasite (4)
By Research Areas:	Cancer (6) Infection (5) Inflammation/Immunology (14) Metabolic Disease (2) Neurological Disease (5)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0914

Ajugol 2 Publications Verification	Parasite	Others
Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC₅₀ of 31.8 μg/mL .

HY-N0820

Catalpol Maximum Cited Publications 8 Publications Verification Catalpinoside	HBV	Infection Neurological Disease Inflammation/Immunology Cancer
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-N5086

Picroside IV	HBV	Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-N8046

Gardoside	Others	Others
Gardoside is an iridoid glycoside that can be found in the roots of L. alba .

HY-N2712

6''-O-trans-Feruloylcatalpol	Others	Others
6''-O-trans-Feruloylcatalpol is a natural iridoid glycoside compound .

HY-N1206

Specioside 6-O-(E)-p-Coumaroylcatalpol	Others	Others
Specioside is a novel iridoid glycoside extracted from Catalpa speciosa Warder (Bignoniaceae) .

HY-N11712

8-Dehydroxyshanzhiside	Others	Others
8-Dehydroxyshanzhiside is an iridoid glycoside that can be isolated from Lamiophlomis rotata .

HY-133109

Trachelosiaside	Others	Others
Trachelosiaside is a natural organic compound belonging to the class of iridoid glycosides. Trachelosiaside is found in various plant species, especially in the roots of Trachelospermum jasminoides. Trachelosiaside has potential medicinal properties, such as anti-inflammatory, antioxidant, and anti-tumor effects. Trachelosiaside has industrial applications in the production of food supplements, cosmetics and pharmaceuticals.

HY-N0914R

Ajugol (Standard)	Parasite	Others
Ajugol (Standard) is the analytical standard of Ajugol. This product is intended for research and analytical applications. Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC₅₀ of 31.8 μg/mL .

HY-N0820R

Catalpol (Standard)	HBV	Infection Neurological Disease Inflammation/Immunology Cancer
Catalpol (Standard) is the analytical standard of Catalpol. This product is intended for research and analytical applications. Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-125543

Karsoside	Others	Others
Karsoside is an iridoid glycoside that can be isolated from Scrophularia ilwensis .

HY-N13109

Caprarioside	Others	Others
Caprarioside is an iridoid glycoside that can be isolated from Capraria biflora L. .

HY-N11794

7-Ketologanin	Others	Others
7-Ketologanin is an iridoid glucoside. 7-Ketologanin can be isolated from the Stems of Viburnum erosum. 7-Ketologanin involves in biosynthetic pathway of oleuropein. Oleuropein, is a bioactive phenolic compound, modulates several oncogenic signalling pathways .

HY-N9352

Cantleyoside	Others	Others
Cantleyoside is a natiural iridoid glycoside that could be found in the Roots of Dipsacus asper .

HY-N2015

Hastatoside	Others	Neurological Disease
Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep .

HY-N0512

Loganin 3 Publications Verification Loganoside	Apoptosis	Cancer
Loganin is the main iridoid glycoside compound in Cornus officinalis and has anti-inflammatory and anti-shock effects.

HY-N0409

Picroside III	Others	Inflammation/Immunology
Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .

HY-N4221

6'-O-Cinnamoyl harpagide	Others	Others
6'-O-Cinnamoyl harpagide is an iridoid glycoside isolated from the roots of Scrophularia ningpoensis .

HY-N3839

epi-Vogeloside 7-epi-Vogeloside; Nervoside; Epivogeloside	Others	Others
epi-Vogeloside is a secoiridoid glycoside and a iridoid glucoside, which can be isolated from Lonicera japonica Thunb .

HY-N12840

Logmalicid B	Interleukin Related	Metabolic Disease
Logmalicid B is an iridoid glycoside compound that can be isolated from Cornus officinalis and can be used in diabetes research .

HY-N12202

6′-O-β-D-Glucopyranosylphlorigidoside C	Others	Others
6′-O-β-D-Glucopyranosylphlorigidoside C (compound 1) is an iridoid glycoside that can be isolated from Lamiophlomis rotata .

HY-N6008

7-O-Methyl morroniside	Others	Others
7-O-Methyl morroniside is an iridoid glycoside (IG) extracted from Cornus officinalis fructus, used in many traditional Chinese medicines .

HY-N0648

Monotropein	Others	Inflammation/Immunology
Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model .

HY-N2015R

Hastatoside (Standard)	Others	Neurological Disease
Hastatoside (Standard) is the analytical standard of Hastatoside. This product is intended for research and analytical applications. Hastatoside is an iridoid glycoside that is isolated from Verbena officinalis and has a role in promoting sleep .

HY-N0512R

Loganin (Standard)	Apoptosis	Cancer
Loganin (Standard) is the analytical standard of Loganin. This product is intended for research and analytical applications. Loganin is the main iridoid glycoside compound in Cornus officinalis and has anti-inflammatory and anti-shock effects.

HY-N0494

Gentiopicroside 1 Publications Verification Gentiopicrin	Cytochrome P450 HCV	Inflammation/Immunology
Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC₅₀ and a K_i of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.

HY-N2094

Genipin 1-β-D-gentiobioside 1 Publications Verification Genipin 1-gentiobioside; Genipin 1-β-gentiobioside; Genipin gentiobioside	Others	Inflammation/Immunology
Genipin 1-β-D-gentiobioside (Genipin 1-gentiobioside) is one of the most abundant and bioactive iridoid glycosides in Gardenia jasminoides Ellis, which possesses hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.

HY-N0648R

Monotropein (Standard)	Others	Inflammation/Immunology
Monotropein (Standard) is the analytical standard of Monotropein. This product is intended for research and analytical applications. Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model .

HY-N0494R

Gentiopicroside (Standard)	Cytochrome P450 HCV	Inflammation/Immunology
Gentiopicroside (Standard) is the analytical standard of Gentiopicroside. This product is intended for research and analytical applications. Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.

HY-N3552

Catalposide	NF-κB	Inflammation/Immunology
Catalposide, an iridoid glycoside that could be isolated from Catalpa ovate G. Don (Bignoniaceae), inhibits TNF-α, IL-1β, and IL-6 productions and NF-κB (p65) activation in lipopolysaccharide-activated RAW 264.7 macrophages .

HY-N6246

Asperulosidic Acid	NF-κB ERK	Inflammation/Immunology Cancer
Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-N0397

Harpagide	Parasite	Infection Inflammation/Immunology
Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (*T.b. rhodesiense) with an IC₅₀* of 21 μg/mL. Harpagide exerts significant antileishmanial activity against *L. donovani* with an IC₅₀ value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .

HY-N12203

5-Deoxypulchelloside I	Others	Others
5-Deoxypulchelloside I is a magnoside glycoside that can be isolated from the aerial parts of the Lamiaceae plant Eremostachys laciniata .

HY-121125

Aucubigenin	Others	Others
Aucubigenin, the aglycone of the iridoid glycoside aucubin, has been characterized through X-ray diffraction analysis. Its crystal structure reveals monoclinic symmetry with specific conformations adopted by its cyclopentane and pyran rings. The study also determined the absolute configurations of both aucubin and aucubigenin. Significant O–H?O hydrogen bonding interactions were observed in the crystal lattices of both compounds, highlighting their structural stability and potential for intermolecular interactions .

HY-N6246R

Asperulosidic Acid (Standard)	NF-κB ERK	Inflammation/Immunology Cancer
Asperulosidic Acid (Standard) is the analytical standard of Asperulosidic Acid. This product is intended for research and analytical applications. Asperulosidic Acid (ASPA), a bioactive iridoid glycoside, is extracted from the herbs of Hedyotis diffusa Willd. Asperulosidic Acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities . ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways .

HY-N0397R

Harpagide (Standard)	Parasite	Infection Inflammation/Immunology
Harpagide (Standard) is the analytical standard of Harpagide. This product is intended for research and analytical applications. Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC₅₀ of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC₅₀ value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .

Ajugol 2 Publications Verification	Structural Classification Iridoids Classification of Application Fields Terpenoids Labiatae Source classification Other Diseases Scrophulariaceae Lactuca perennis Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Disease Research Fields	Parasite
Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC₅₀ of 31.8 μg/mL .

Catalpol Maximum Cited Publications 8 Publications Verification Catalpinoside	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Infection Iridoids Terpenoids Scrophulariaceae Inflammation/Immunology Disease Research Fields Cancer	HBV
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

Picroside IV	Structural Classification Neurological Disease Classification of Application Fields Source classification Metabolic Disease Plants Monophenols Iridoids Terpenoids Phenols Scrophulariaceae Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields	HBV
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

Gardoside	Iridoids Classification of Application Fields Terpenoids Source classification Other Diseases Rubiaceae Plants Gardenia jasminoides Ellis Disease Research Fields	Others
Gardoside is an iridoid glycoside that can be found in the roots of L. alba .

6''-O-trans-Feruloylcatalpol	Structural Classification Iridoids Euryops arabicus Steud. ex Jaub. & Spach Terpenoids Labiatae Source classification Plants	Others
6''-O-trans-Feruloylcatalpol is a natural iridoid glycoside compound .

Specioside 6-O-(E)-p-Coumaroylcatalpol	Structural Classification Iridoids Catalpa speciosa (Warder ex Barney) Engelm. Terpenoids Source classification Bignoniaceae Plants	Others
Specioside is a novel iridoid glycoside extracted from Catalpa speciosa Warder (Bignoniaceae) .

8-Dehydroxyshanzhiside	Structural Classification Ketones, Aldehydes, Acids Labiatae Phaseolus lunatus L. Source classification Plants	Others
8-Dehydroxyshanzhiside is an iridoid glycoside that can be isolated from Lamiophlomis rotata .

Trachelosiaside	Apocynaceae Structural Classification Source classification Trachelospermum lucidum (D.Don) K.Schum. Coumarins Phenylpropanoids Plants	Others
Trachelosiaside is a natural organic compound belonging to the class of iridoid glycosides. Trachelosiaside is found in various plant species, especially in the roots of Trachelospermum jasminoides. Trachelosiaside has potential medicinal properties, such as anti-inflammatory, antioxidant, and anti-tumor effects. Trachelosiaside has industrial applications in the production of food supplements, cosmetics and pharmaceuticals.

Ajugol (Standard)	Structural Classification Iridoids Terpenoids Labiatae Source classification Scrophulariaceae Lactuca perennis Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey	Parasite
Ajugol (Standard) is the analytical standard of Ajugol. This product is intended for research and analytical applications. Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC₅₀ of 31.8 μg/mL .

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Iridoid Glycoside

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