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Results for "

Kv3

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

3

Peptides

1

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-128829
    Kv3 modulator 2

    		Potassium Channel Inflammation/Immunology
    Kv3 modulator 2 (formula (I)) is a potent Kv3 channels modulator extracted from patent WO2018109484A1, compound formula (I) , has analgesic activity and is used in the prophylaxis or treatment of related disorders .
    Kv3 modulator 2
  • HY-117639
    AUT1

    		Potassium Channel Neurological Disease
    AUT1 is a recombinant human Kv3 channel modulator. AUT1 modulates Kv3.1b and Kv3.2a channels in human recombinant with pEC50 values of 5.33 and 5.31 μM, respectively. AUT1 can be used for the research of disorders associated with dysfunction of inhibitory feedback in corticolimbic circuits, such as schizophrenia .
    AUT1
  • HY-108574
    CP 339818 hydrochloride

    		Potassium Channel Neurological Disease
    CP 339818 hydrochloride is a nonpeptide and selective Kv1.3 (IC50 value of ~200 nM) and Kv1.4 channels blocker. CP 339818 hydrochloride is a significantly less potent blocker of Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation .
    CP 339818 hydrochloride
  • HY-153746
    Kv3 modulator 5

    		Potassium Channel Neurological Disease
    Kv3 modulator 5 (Example 5) is a Kv3 channel modulator. Kv3 modulator 5 increases the Kv3.2 current. Kv3 modulator 5 can be used for research of hearing disorders .
    Kv3 modulator 5
  • HY-128831
    Kv3 modulator 4

    		Potassium Channel Inflammation/Immunology
    Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator extracted from patent WO2018020263A1, Cyclobutyl structure .
    Kv3 modulator 4
  • HY-128830
    Kv3 modulator 3

    		Potassium Channel Inflammation/Immunology
    Kv3 modulator 3 (Compound 4) is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels extracted from patent WO2017098254A1, compound 4, has analgesic activity for use in the prophylaxis o or treatment of pain .
    Kv3 modulator 3
  • HY-111996
    Kv3 modulator 1

    		Potassium Channel Inflammation/Immunology
    Kv3 modulator 1 is a Kv3 voltage-gated potassium channel modulator extracted from patent WO2018020263A1, Compound X. Kv3 modulator 1 has the potential for inflammatory pain treatment .
    Kv3 modulator 1
  • HY-163018
    Kv3.1 modulator 2

    		Others Neurological Disease
    Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM .
    Kv3.1 modulator 2
  • HY-P5818
    BDS-II

    		Sodium Channel Neurological Disease
    BDS-II is a peptide toxin, and is composed of 43 amino acids. BDS-II is a selective Kv3.4 channel inhibitor .
    BDS-II
  • HY-P5156
    BDS-I

    		Potassium Channel Neurological Disease
    BDS-I known as blood depressing substance, is a marine toxin which can be extracted from Anemonia sulcata. BDS-I is a specific inhibitor of Potassium Channel, targeting to Kv3.4. BDS-I inhibits Aβ1-42-induced enhancement of KV3.4 activity, caspase-3 activation, and abnormal nuclear morphology of NGF-differentiated PC-12 cells. BDS-I reverts the Aβ peptide-induced cell death .
    BDS-I
  • HY-114540
    CP-339818

    		Others Neurological Disease
    CP-339818 is a non-peptide drug with potent Kv1.3 channel blocking activity. CP-339818 is able to effectively inhibit the activation of human T cells. By selectively blocking Kv1.3, CP-339818 is of great value in immune system research. The drug inhibits the C-type inactivated state of Kv1.3 channels in a use-dependent manner. CP-339818 has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels, and only shows some inhibition on the Kv1.4 channel .
    CP-339818

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