2. Membrane Transporter/Ion Channel
  3. Potassium Channel
  4. Kv3 modulator 2

Kv3 modulator 2 (formula (I)) is a potent Kv3 channels modulator extracted from patent WO2018109484A1, compound formula (I) , has analgesic activity and is used in the prophylaxis or treatment of related disorders.

For research use only. We do not sell to patients.

Kv3 modulator 2 Chemical Structure

Kv3 modulator 2 Chemical Structure

CAS No. : 2101321-76-8

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5 mg USD 850 In-stock
10 mg USD 1450 In-stock
25 mg USD 2800 In-stock
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Based on 1 publication(s) in Google Scholar

Kv3 modulator 2 Related Antibodies

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Description

Kv3 modulator 2 (formula (I)) is a potent Kv3 channels modulator extracted from patent WO2018109484A1, compound formula (I) , has analgesic activity and is used in the prophylaxis or treatment of related disorders[1].

IC50 & Target

Kv3 channels[1]
Molecular Weight

379.41

Formula

C21H21N3O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C=C1)=C2C(C3(CO2)CC3)=C1OC4=CN=C(N5C([C@@H](CC)NC5=O)=O)C=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (263.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6357 mL 13.1784 mL 26.3567 mL
5 mM 0.5271 mL 2.6357 mL 5.2713 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6357 mL 13.1784 mL 26.3567 mL 65.8918 mL
5 mM 0.5271 mL 2.6357 mL 5.2713 mL 13.1784 mL
10 mM 0.2636 mL 1.3178 mL 2.6357 mL 6.5892 mL
15 mM 0.1757 mL 0.8786 mL 1.7571 mL 4.3928 mL
20 mM 0.1318 mL 0.6589 mL 1.3178 mL 3.2946 mL
25 mM 0.1054 mL 0.5271 mL 1.0543 mL 2.6357 mL
30 mM 0.0879 mL 0.4393 mL 0.8786 mL 2.1964 mL
40 mM 0.0659 mL 0.3295 mL 0.6589 mL 1.6473 mL
50 mM 0.0527 mL 0.2636 mL 0.5271 mL 1.3178 mL
60 mM 0.0439 mL 0.2196 mL 0.4393 mL 1.0982 mL
80 mM 0.0329 mL 0.1647 mL 0.3295 mL 0.8236 mL
100 mM 0.0264 mL 0.1318 mL 0.2636 mL 0.6589 mL
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Kv3 modulator 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kv3 modulator 22101321-76-8Potassium ChannelKcsAInhibitorinhibitorinhibit

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