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LOXL4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Monoamine Oxidase (4) Small Interfering RNA (siRNA) (1)
By Research Areas:	Inflammation/Immunology (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

PXS-6302 hydrochloride	Monoamine Oxidase	Inflammation/Immunology
PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC₅₀s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .

PXS-4787 hydrochloride	Monoamine Oxidase	Others
PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC₅₀s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts .

LOXL4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LOXL4 Human Pre-designed siRNA Set A contains three designed siRNAs for LOXL4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LOXL4 Human Pre-designed siRNA Set A LOXL4 Human Pre-designed siRNA Set A

PXS-4787	Monoamine Oxidase	Others
PXS-4787 is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 inhibits LOX with IC₅₀s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively .

PXS-6302	Monoamine Oxidase	Others
PXS-6302 is an irreversible lysyl oxidase inhibitor with IC₅₀s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .

Cat. No.	Compare	Product Name	Species	Source

	LOXL4 Protein, Human (His) LOXC; Lysyl oxidase-like 4	Human	E. coli
	LOXL4 Protein, Human (His) is the recombinant human-derived LOXL4, expressed by E. coli , with C-6*His labeled tag. ,

	Lysyl oxidase homolog 4 Protein, Mouse (His) LOXL4; Loxc; Lysyl oxidase homolog 4; EC 1.4.3.-; Lysyl oxidase-like protein 4; Lysyl oxidase-related protein C	Mouse	E. coli
	LOXL4 Protein potentially modulates collagenous extracellular matrix formation, suggesting a role in regulating assembly or stability of collagen fibers. Its involvement indicates a contribution to the structural integrity of tissues. The specific mechanisms and contexts of LOXL4 in collagen matrix modulation are areas of interest, emphasizing its potential significance in tissue development and maintenance. Lysyl oxidase homolog 4 Protein, Mouse (His) is the recombinant mouse-derived Lysyl oxidase homolog 4 protein, expressed by E. coli , with N-His labeled tag.

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LOXL4 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
LOXL4 Human Pre-designed siRNA Set A contains three designed siRNAs for LOXL4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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