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Results for "

NODAL

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Adrenergic Receptor (2) Autophagy (2) Calcium Channel (3) Cytochrome P450 (2) mAChR (2) Organoid (1) Small Interfering RNA (siRNA) (1) Sodium Channel (2) TGF-β Receptor (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (4)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

A 83-01 40+ Cited Publications	Organoid TGF-β Receptor	Cancer
A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC₅₀s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively .

Etripamil MSP-2017; (-)-MSP-2017	Calcium Channel	Cardiovascular Disease
Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist, can be used for the research of Paroxysmal Supraventricular Tachycardia (PSVT). Etripamil (MSP-2017) slows atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells .

Dronedarone 1 Publications Verification SR 33589	mAChR Sodium Channel Calcium Channel Adrenergic Receptor Cytochrome P450 Autophagy	Cardiovascular Disease
Dronedarone (SR 33589), a derivative of amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone is a substrate for and a moderate inhibitor of CYP3A4 .

NODAL Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NODAL Human Pre-designed siRNA Set A contains three designed siRNAs for NODAL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NODAL Human Pre-designed siRNA Set A NODAL Human Pre-designed siRNA Set A

CVT-2759	Adenosine Receptor	Cardiovascular Disease
CVT-2759 is a potent inhibitor of A₁-ADOR, with the IC₅₀ values of 0.18 μM and 9.5 μM to reduce the binding of [3H]CPX in the absence and presence of 1 mM GTP. CVT-2759 plays an important role in slowing AV nodal conduction and thereby ventricular rate without causing AV block, bradycardia, atrial arrhythmias, or vasodilation .

Dronedarone (Standard)	mAChR Sodium Channel Calcium Channel Adrenergic Receptor Cytochrome P450 Autophagy	Cardiovascular Disease
Dronedarone (Standard) is the analytical standard of Dronedarone. This product is intended for research and analytical applications. Dronedarone (SR 33589), a derivative of amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone is a substrate for and a moderate inhibitor of CYP3A4 .

Cat. No.	Compare	Product Name	Species	Source

	*Animal-Free Nodal* Protein, Human (His)** 1 Publications Verification NODAL	Human	E. coli
	Nodal protein plays a key role in embryonic development and is indispensable for mesoderm formation and axial patterning. As a homodimer linked together by disulfide bonds, Nodal helps form the molecular framework that controls fundamental developmental pathways, ensuring the correct establishment of mesodermal tissue and axial structure during embryogenesis. Animal-Free Nodal Protein, Human (His) is the recombinant human-derived animal-FreeNodal protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free Nodal Protein, Human (His) is 110 a.a., with molecular weight of ~13.75 kDa.

	Nodal Protein, Mouse NODAL; Tg.413d	Mouse	E. coli
	Nodal protein plays a key role in embryonic development and is integral for mesoderm formation and axial patterning. Its involvement in these fundamental processes underscores its importance in coordinating the complex series of events that determine early embryonic morphogenesis. Nodal Protein, Mouse is the recombinant mouse-derived Nodal protein, expressed by E. coli , with tag free.

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	Nodal Antibody (YA1410) HTX5	WB	Human, Mouse, Rat
	Nodal Antibody (YA1410) is a biotin-conjugated non-conjugated IgG antibody, targeting Nodal, with a predicted molecular weight of 40 kDa (observed band size: 40 kDa). Nodal Antibody (YA1410) can be used for WB experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

NODAL Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
NODAL Human Pre-designed siRNA Set A contains three designed siRNAs for NODAL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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