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Results for "

RCC

" in MedChemExpress (MCE) Product Catalog:

14

Inhibitors & Agonists

2

Peptides

1

Inhibitory Antibodies

10

Recombinant Proteins

1

Isotope-Labeled Compounds

3

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-I0636
    (R)-Apremilast

    (R)-CC-10004

    		 Others Inflammation/Immunology
    (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast .
    (R)-Apremilast
  • HY-100746
    STF-62247
    1 Publications Verification

    		 Autophagy Cancer
    STF-62247 is an autophagy inducer that selectively cytotoxic to VHL-deficient renal cell carcinoma (IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively) .
    STF-62247
  • HY-119425
    Razoxane

    ICRF 159

    		 Topoisomerase Cancer
    Razoxane (ICRF 159) is an antiangiogenic topoisomerase II inhibitor, can be used for the research of renal cell carcinoma (RCC) .
    Razoxane
  • HY-139782
    SKLB325

    		Histone Demethylase Apoptosis Cancer
    SKLB325 is a Jumonji domain-containing 6 (JMJD6) inhibitor with a binding affinity (KD) value of 0.755?μM, and the IC50 value of 0.7797?μM. SKLB325 exhibits antitumor effects on ovarian cancer in vivo and in vitro. SKLB325 induces apoptosis . SKLB325 exhibits remarkable antitumor efficacy in renal cell carcinoma (RCC) .
    SKLB325
  • HY-P99161
    Tilvestamab

    BGB149

    		 TAM Receptor Cancer
    Tilvestamab (BGB149) is a humanized anti-AXL antibody that blocks AXL-mediated cell signaling. Tilvestamab significantly inhibits Gas6-induced AXL activation in 786-0-Luc RCC cells and inhibits downstream AKT phosphorylation. Tilvestamab can be used in cancer research, particularly in AXL overexpressing renal cell carcinomas .
    Tilvestamab
  • HY-18728
    STF-31
    Maximum Cited Publications
    12 Publications Verification

    		 GLUT Autophagy Cancer
    STF-31 is a selective inhibitor of glucose transporter 1 (GLUT1), with an IC50 of 1 μM. STF-31 is also a NAMPT inhibitor. STF-31 inhibits glucose uptake in renal cell carcinoma (RCC) 4 cells .
    STF-31
  • HY-122615
    SPOP-IN-6b
    1 Publications Verification

    		 Others Cancer
    SPOP-IN-6b is a speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM (patent CN 107141287, SPOP-B-88) .
    SPOP-IN-6b
  • HY-RS11783
    RCC1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    RCC1 Human Pre-designed siRNA Set A contains three designed siRNAs for RCC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RCC1 Human Pre-designed siRNA Set A
    RCC1 Human Pre-designed siRNA Set A
  • HY-RS11784
    RCC2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    RCC2 Human Pre-designed siRNA Set A contains three designed siRNAs for RCC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RCC2 Human Pre-designed siRNA Set A
    RCC2 Human Pre-designed siRNA Set A
  • HY-12085S2
    (Rac)-Apremilast-d5

    (Rac)-CC-10004 d5

    		 Apoptosis Phosphodiesterase (PDE) TNF Receptor Isotope-Labeled Compounds Inflammation/Immunology
    (Rac)-Apremilast-d5 is a deuterium labeled (R)-Apremilast. (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast[1].
    (Rac)-Apremilast-d5
  • HY-P2324
    Gramicidin A
    1 Publications Verification

    		 Bacterial HIF/HIF Prolyl-Hydroxylase Antibiotic Infection Cancer
    Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α) .
    Gramicidin A
  • HY-P2324A
    Gramicidin A TFA

    		Antibiotic Bacterial Infection
    Gramicidin A (TFA) is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A (TFA) is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A (TFA) induces degradation of hypoxia inducible factor 1 α (HIF-1α) .
    Gramicidin A TFA
  • HY-112780
    UC2288
    4 Publications Verification

    		 MDM-2/p53 Cancer
    UC2288 is a novel, cell-permeable, and orally active p21 attenuator (relatively selective activity for p21), which is synthesized based Sorafenib (HY-10201). UC2288 decreases p21 mRNA expression independently of p53, and attenuates p21 protein levels with minimal effect on p21 protein stability. UC2288 has no inhibition of VEGFR2 and Raf kinases even at 10 μM .
    UC2288
  • HY-112467
    Tivozanib hydrate
    5+ Cited Publications

    AV-951 hydrate; KRN951 hydrate

    		 VEGFR Cancer
    Tivozanib hydrate (AV-951 hydrate; KRN951 hydrate) is the hydrate form of Tivozanib (HY-10977). Tivozanib hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC50s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrate exhibits antitumor efficacy .
    Tivozanib hydrate

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