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Results for "

ZIKV E protein

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Natural
Products

10

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N12340
    Wulfenioidin H

    		Flavivirus Infection
    Wulfenioidin H (Compound 5) is a diterpenoid, exhibits activity against Zika virus (ZIKV) with an EC50 value 8.50 μM. Wulfenioidin H interferes with the replication of the ZIKV by inhibiting the expression of the ZIKV envelope (E) protein .
    Wulfenioidin H
  • HY-N12339
    Wulfenioidin F

    		Virus Protease Infection
    Wulfenioidin F is a diterpenoid, that can be isolated from the whole plant of Orthosiphon wulfenioides. Wulfenioidin F exhibits activity against Zika virus (ZIKV) with an EC50 of 8.07 μM. Wulfenioidin F interferes with the replication of the ZIKV by inhibiting the expression of the ZIKV envelope (E) protein .
    Wulfenioidin F
  • HY-146957
    ZIKV-IN-1

    		Virus Protease Flavivirus Cancer
    ZIKV-IN-1 is a potent zika virus inhibitor with an EC50 of 2.8 μM and EC90 of 6.8 μM. ZIKV-IN-1 shows anti-ZIKV activity with low cytotoxicity. ZIKV-IN-1 shows a strong affinity to ZIKV RdRp domain . ZIKV-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    ZIKV-IN-1
  • HY-161804
    GNF-2-deg

    		PROTACs Dengue virus Infection
    GNF-2-deg is a PROTAC degrader for dengue virus envelope protein (DENV E protein) with DC50 of 0.83 μM. GNF-2-deg prevents viral entry by inhibiting E-mediated membrane fusion, prevents virion production by protein degradation, and thereby exhibits antiviral activity against DENV 2 with EC90 of 3.5 μM. GNF-2-deg exhibits antiviral activity against ZIKV, JEV, WNV and YFV with EC90 of 1.96-7.79 μM. (Pink: ligand for target protein (HY-161805); Black: linker (HY-42149); Blue: ligand for E3 ligase (HY-23095))
    GNF-2-deg

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