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Results for "

calcium ionophore

" in MedChemExpress (MCE) Product Catalog:

22

Inhibitors & Agonists

8

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136460

    ETH 1001

    Calcium Channel Others
    Calcium ionophore I (ETH 1001) is a selective Ca 2+ ionophore for biological membranes. Calcium ionophore I can be used in Ca2+-selective microelectrodes that can be used for quantitative intracellular measurements of resting Ca2+-activities and of slowly changing Ca2+-levels .
    Calcium ionophore I
  • HY-139728

    calcium ionophore II

    Others Others
    N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide (Calcium ionophore II) is a lipophilic ionophore that can be used in preparing calcium ion-selective electrode .
    N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide
  • HY-13434A
    Ionomycin calcium
    Maximum Cited Publications
    61 Publications Verification

    SQ23377 calcium

    Calcium Channel PKC Bacterial Apoptosis Antibiotic Infection Cancer
    Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) .
    Ionomycin calcium
  • HY-13434
    Ionomycin
    Maximum Cited Publications
    61 Publications Verification

    SQ23377

    Calcium Channel PKC Bacterial Apoptosis Antibiotic Infection Cancer
    Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) .
    Ionomycin
  • HY-N6694

    Calcium Channel Bacterial Apoptosis Antibiotic Infection Cancer
    4-Bromo A23187 is a halogenated analog of the highly selective calcium ionophore A-23187. 4-Bromo A23187, a calcium modulator, induces apoptosis in different cells, including HL-60 cells .
    4-Bromo A23187
  • HY-125703

    Estrogen Receptor/ERR Apoptosis Infection Inflammation/Immunology Endocrinology Cancer
    Ferutinin, a natural terpenoid compound, is an estrogen receptor ERα agonist and estrogen ERβ-receptor agonist/antagonist with IC50s of 33.1 nM and 180.5 nM, respectively. Ferutinin acts as an electrogenic Ca 2+-ionophore that increases calcium permeability of lipid bilayer membranes, mitochondria. Ferutinin possesses estrogenic, antitumor, antibacterial and antiinflammatory activities .
    Ferutinin
  • HY-W674112

    ETH 1117

    Others Others
    Magnesium ionophore I (ETH 1117) serves as the primary component for the development of calcium-magnesium selective electrodes.
    Magnesium ionophore I
  • HY-B1327S

    7-Chlorotetracycline-d6 hydrochloride

    Bacterial Antibiotic Infection
    Chlortetracycline-d6 (hydrochloride) is the deuterium labeled Chlortetracycline hydrochloride. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic, inhibits binding of aminoacyl-tRNA to ribosomes.
    Chlortetracycline-d6 hydrochloride
  • HY-120539

    BI-L-239

    Lipoxygenase Leukotriene Receptor Inflammation/Immunology
    Enofelast (BI-L-239), a 5-lipoxygenase (5-LO) inhibitor, exhibits an IC50 of 2.48 μM for inhibition of calcium ionophore-induced LTB4 generation .
    Enofelast
  • HY-B1327R

    Bacterial Antibiotic Parasite Infection Inflammation/Immunology
    Chlortetracycline (hydrochloride) (Standard) is the analytical standard of Chlortetracycline (hydrochloride). This product is intended for research and analytical applications. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic that inhibits the binding of aminoacyl-tRNA to ribosomes.
    Chlortetracycline hydrochloride (Standard)
  • HY-10437A

    MK-0633 tosylate

    Lipoxygenase Inflammation/Immunology
    Setileuton tosylate is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively .
    Setileuton tosylate
  • HY-10437

    MK-0633

    Lipoxygenase Inflammation/Immunology
    Setileuton (MK-0633) is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively .
    Setileuton
  • HY-N1204

    Others Others
    Soyacerebroside II is a calcium ionophoretic sphingoglycolipid that can be isolated from Soybean .
    Soyacerebroside II
  • HY-123103

    Lipoxygenase Histamine Receptor Inflammation/Immunology
    Linetastine is an orally active and potent 5-Lipoxygenase inhibitor. Linetastine shows antihistamine activity. Linetastine inhibits leukotriene production and antagonizes the effect of histamine. Linetastine inhibits the release of leukotrienes B4 and C4 from calcium ionophore-stimulated human leukocytes .
    Linetastine
  • HY-N6687
    Calcimycin
    5+ Cited Publications

    A-23187; Antibiotic A-23187

    Oxidative Phosphorylation Bacterial Fungal Apoptosis Autophagy Antibiotic Infection Cancer
    Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis .
    Calcimycin
  • HY-B1327
    Chlortetracycline hydrochloride
    3 Publications Verification

    7-Chlorotetracycline hydrochloride

    Bacterial Antibiotic Parasite Infection Inflammation/Immunology
    Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline hydrochloride is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes .
    Chlortetracycline hydrochloride
  • HY-B1327A

    7-Chlorotetracycline

    Bacterial Antibiotic Parasite Infection Inflammation/Immunology
    Chlortetracycline (7-Chlorotetracycline) is an orally active, effective and selectively methanogenic bacteria inhibitor with bactericidal effects. Chlortetracycline is also a antibiotic that acts by inhibiting bacterial protein synthesis. Additionally, Chlortetracycline is a specific and potent calcium ionophore antibiotic, inhibiting binding of aminoacyl-tRNA to ribosomes .
    Chlortetracycline
  • HY-N6687B

    A-23187 hemimagnesium; Antibiotic A-23187 hemimagnesium

    Oxidative Phosphorylation Bacterial Fungal Apoptosis Autophagy Infection Cancer
    Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis .
    Calcimycin hemimagnesium
  • HY-N6687A

    A-23187 hemicalcium salt; Antibiotic A-23187 hemicalcium salt

    Oxidative Phosphorylation Bacterial Fungal Apoptosis Autophagy Antibiotic Infection Cancer
    Calcimycin hemicalcium salt (A-23187 hemicalcium salt) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemicalcium salt induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemicalcium salt inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemicalcium salt also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemicalcium salt induces apoptosis .
    Calcimycin hemicalcium salt
  • HY-145473

    15(S)-HETE-SAPE; 15(S)-Hydroxyeicosatetraenoic acid-SAPE; 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine

    Others Metabolic Disease
    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.
    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE
  • HY-108611
    AACOCF3
    3 Publications Verification

    Arachidonyl trifluoromethyl ketone

    Phospholipase Cardiovascular Disease
    AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease .
    AACOCF3
  • HY-112825

    Others Inflammation/Immunology
    Platelet-activating factor (PAF) is a pro-inflammatory phospholipid mediator that is rapidly synthesized by lyso-PAF acetyltransferase (lyso-PAFAT) in response to extracellular stimuli. Two types of lyso-PAFAT have been identified: lysophosphatidylcholine acyltransferase (LPCAT)1, which is mostly expressed in the lungs, and LPCAT2, which is expressed in inflammatory cells. TSI-01 is a selective inhibitor of LPCAT2 (IC50s=0.47 versus 3.02 μM for human LPCAT2 and LPCAT1, respectively). 60 μM it is shown to suppress PAF biosynthesis in mouse peritoneal macrophages stimulated with a calcium ionophore.
    TSI-01

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