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cytosol

" in MedChemExpress (MCE) Product Catalog:

27

Inhibitors & Agonists

7

Biochemical Assay Reagents

12

Peptides

1

Inhibitory Antibodies

1

Natural
Products

6

Recombinant Proteins

2

Isotope-Labeled Compounds

3

Oligonucleotides

Cat. No. Product Name Target Research Area
  • HY-P6012A

    Peptides Others
    SAIRGA (TFA), derived from the phages phi3T, can recognize phAimR in the bacterial cytosol to induce lysogeny .
  • HY-P6011A

    Peptides Others
    GMPRGA (TFA) is the TFA form of GMPRGA (HY-P6011). GMPRGA (TFA) can recognize spAimR in the bacterial cytosol to induce lysogeny .
  • HY-P2500

    Peptides Others
    (Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .
  • HY-P1928

    Bcl-2 Family Neurological Disease Endocrinology
    Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity. Humanin also improves overall insulin sensitivity in animal. Humanin are related to aging .
    Humanin analogue, in which the serine at position 14 is replaced by glycine, names HNG .
  • HY-P4121

    Peptides Metabolic Disease
    L17E, an endosomolytic peptide, is a cationic amphiphilic peptide with specific membrane lytic activity for late endosomes (LEs). L17E diminishes the TS5-p45 induced apoptosis in a dose-dependent manner. L17E is endocytosed into cells and trafficked to LEs. Within the acidic environment of LEs, L17E perturbs and lyses the LE membrane, leading to disruption of LE membrane and release of LE content to the cytosol. L17E is used to investigate the role of the endosomal protein trafficking pathway .
  • HY-P6011

    Peptides Others
    GMPRGA, derived from the phages Spbeta, can recognize spAimR in the bacterial cytosol to induce lysogeny .
  • HY-P6012

    Peptides Others
    SAIRGA, derived from the phages phi3T, can recognize phAimR in the bacterial cytosol to induce lysogeny .
  • HY-P1425

    Peptides Neurological Disease
    (Z-LL)2 ketone is an inhibitor of ketone with an IC50 value of 50 nM. (Z-LL)2 ketone promotes the release of an N-terminal fragment into the cytosol .
  • HY-P10632

    Peptides Others
    HiBiT tag is a complimentary peptide (VSGWRLFKKIS), with high affinity for LgBiT. HiBiT tag is fused to the Gβ subunit of the receptor. The complementation of LgBiT and HiBiT facilitates the stabilization of ETR and G protein. HiBiT is attached to a protein of interest (GFP) to quantify transport to the cytosol .
  • HY-P10153

    Peptides Others
    gH625 is a cell-penetrating viral peptide which is a part of glycoprotein H of Herpes simplex virus type I. gH625 is able to cross the cell membrane and to transport many conjugated cargoes into the cytosol. gH625 is permeable to the blood-brain barrier (BBB) and can enter the rat brain in vivo without toxic effects. gH625 can be used for siRNA delivery research .
  • HY-P2048

    Peptides Others
    MOTS-c (human) is a biological active peptide. (Recent advances in high-resolution sequencing have led to the discovery of unique peptides derived from mitochondrial genome.1-2 Currently 8 peptides are identified: humanin, mitochondrial open reading frame of the 12S tRNA-c (MOTS-c), and six small humanin-like peptides (SHLP1-6). 1-2 All of these peptides are released into cytosol from mitochondria and associate with increased longevity and cell viability, reduced apoptosis, and other beneficial functions. 1-3 MOTS-c was found to reduce insulin resistance, decrease obesity, and promote homeostasis.)
  • HY-P5325

    Bcl-2 Family Others
    Bid BH3 (80-99) is a biological active peptide. (BID is a pro-apoptotic member of the 'BH3-only' (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

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