1. Metabolic Enzyme/Protease
  2. E1/E2/E3 Enzyme
  3. CP26

CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress.

For research use only. We do not sell to patients.

CP26 Chemical Structure

CP26 Chemical Structure

CAS No. : 500285-30-3

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Based on 1 publication(s) in Google Scholar

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Description

CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress[1].

In Vitro

CP26 exhibits a significant inhibitory activity against both DENV and ZIKV, providing substantial protection to the host cells against virus-induced cell death[1].
CP26 inhibits the ubiquitination and degradation of misfolded ER proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

306.01

Formula

C13H8Cl4

CAS No.
Appearance

Solid

Color

Pale purple to purple

SMILES

ClC(C(Cl)=C/1Cl)=C(Cl)C1=C\C2=CC=C(C)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CP26
Cat. No.:
HY-49116
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