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globin

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By Targets:	Antibiotic (1) Histone Methyltransferase (2) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (2)

5

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Natural
Products

3

Recombinant Proteins

1

Isotope-Labeled Compounds

2

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

3-(3,4-Dimethoxyphenyl)propanoic acid	Others	Cardiovascular Disease
3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias .

RK-701	Histone Methyltransferase	Cancer
RK-701 is an highly selective and non-genotoxic inhibitor of G9a with IC₅₀ value of 23-27 nM. RK-701 selectively up-regulates HbF, γ- Globin, BGLT3 expression, down-regulates H3K9me2 expression. RK-701 also has inhibition for BCL11A and ZBTB7A .

cis-Vaccenic acid	Antibiotic	Cancer
cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate , acts a potential fetal hemoglobin inducer .

3-(3,4-Dimethoxyphenyl)propanoic acid-d10	Isotope-Labeled Compounds	Cardiovascular Disease
3-(3,4-Dimethoxyphenyl)propanoic acid-d₁₀ is the deuterium labeled 3-(3,4-Dimethoxyphenyl)propanoic acid. 3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias[1].

G9a-IN-2	Histone Methyltransferase	Others
G9a-IN-2 (Compound 7i) is an inhibitor for histone methyltransferases G9a with IC₅₀ of 0.024 μM. G9a-IN-2 reduces H3K9me2 levels and induces the mRNA expression of γ-globin mRNA. G9a-IN-2 shows the potential in ameliorating sickle cell disease (SCD) .

Cat. No.	Product Name	Type

Myoglobin	Native Proteins
Myoglobin is a small molecular pigment protein formed by binding globin to Heme, which can be reversibly bound to oxygen to form MbO₂, MbO₂ is called oxymyoglobin, and Mb is called deoxymyoglobin. Myoglobin has the role of transporting and storing oxygen in muscle cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

cis-Vaccenic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Cancer	Antibiotic
cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate , acts a potential fetal hemoglobin inducer .

Species:	Human (3)
Tag:	His (3)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

	Hemoglobin subunit zeta/HBAZ Protein, Human (His) rHuHemoglobin subunit zeta/HBAZ, His; Hemoglobin Subunit Zeta; HBAZ; Hemoglobin Zeta Chain; Zeta-globin; HBZ; HBZ2	Human	E. coli
	The hemoglobin zeta subunit (HBAZ) protein acts as an α-type chain in mammalian embryonic hemoglobin. It contributes to the formation of heterotetramers and is involved in various developmental stages. Hemoglobin subunit zeta/HBAZ Protein, Human (His) is the recombinant human-derived Hemoglobin subunit zeta/HBAZ protein, expressed by E. coli , with N-6*His labeled tag. The total length of Hemoglobin subunit zeta/HBAZ Protein, Human (His) is 142 a.a., with molecular weight of ~15.0 kDa.

	Hemoglobin subunit alpha/HBA1 Protein, Human (His) rHuHemoglobin subunit alpha/HBA1, His; Hemoglobin subunit alpha; Alpha-globin; Hemoglobin alpha chain; HBA1; HBH; HBA-T3	Human	E. coli
	Hemoglobin subunit alpha/HBA1 protein plays a crucial role in oxygen transport and gas exchange within the human body. It also acts as a regulator in the cannabinoid receptor pathway by interacting with hemopressin, a CNR1 antagonist. This dual functionality highlights the multifaceted significance of HBA1, contributing not only to vital oxygen transport but also to the modulation of cannabinoid receptor-mediated processes. Hemoglobin subunit alpha/HBA1 Protein, Human (His) is the recombinant human-derived Hemoglobin subunit alpha/HBA1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Hemoglobin subunit alpha/HBA1 Protein, Human (His) is 142 a.a., with molecular weight of ~21 kDa.

	Hemoglobin subunit theta-1/HBQ1 Protein, Human (His) rHuHemoglobin subunit theta-1, His; Hemoglobin subunit theta-1; Hemoglobin theta-1 chain; Theta-1-globin; HBQ1	Human	E. coli
	Hemoglobin subunit theta-1 (HBQ1) is a protein belonging to the globin family. Globulin is a group of proteins involved in oxygen transport and storage. Hemoglobin subunit theta-1/HBQ1 Protein, Human (His) is the recombinant human-derived Hemoglobin subunit theta-1/HBQ1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Hemoglobin subunit theta-1/HBQ1 Protein, Human (His) is 142 a.a., with molecular weight of 15 kDa.

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Cat. No.	Product Name	Chemical Structure

3-(3,4-Dimethoxyphenyl)propanoic acid-d10
3-(3,4-Dimethoxyphenyl)propanoic acid-d₁₀ is the deuterium labeled 3-(3,4-Dimethoxyphenyl)propanoic acid. 3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias[1].

Cat. No.	Compare	Product Name	Application	Reactivity

	Fetal Hemoglobin Antibody (YA2564) Gamma 1 globin; Gamma 2 globin; Gamma A hemoglobin; Gamma globin; Hb F Agamma; Hb F Ggamma; HBG1; HBG2; HBGA; HBGR	WB	Human
	Fetal Hemoglobin Antibody (YA2564) is a biotin-conjugated non-conjugated IgG antibody, targeting Fetal Hemoglobin, with a predicted molecular weight of 16 kDa (observed band size: 12 kDa). Fetal Hemoglobin Antibody (YA2564) can be used for WB experiment in human background.

	Hemoglobin subunit alpha Antibody (YA1173) HBA1; HBA2; Hemoglobin subunit alpha; Alpha-globin; Hemoglobin alpha chain; Hemopressin	IHC-P	Human
	Hemoglobin subunit alpha Antibody (YA1173) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1173), targeting Hemoglobin subunit alpha. Hemoglobin subunit alpha Antibody (YA1173) can be used for IHC-P experiment in human background.

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