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Results for "

self-assembly

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Amyloid-β (5) Apoptosis (3) Autophagy (2) Bacterial (1) Biochemical Assay Reagents (111) Cholinesterase (ChE) (2) MDM-2/p53 (2) Microtubule/Tubulin (1) TMV (3)
By Research Areas:	Cancer (6) Infection (4) Inflammation/Immunology (1) Neurological Disease (7)
Click Chemistry:	Azide (3)

128

Inhibitors & Agonists

111

Biochemical Assay Reagents

Peptides

Natural
Products

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0687

Vindoline	Microtubule/Tubulin	Cancer
Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly .

HY-P1449

Boc-Gly-Gly-Phe-Gly-OH	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-P1449A

Boc-Gly-Gly-Phe-Gly-OH TFA	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-P4808A

PHF6 TFA	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is mapped to the third microtubule-binding repeat region of the tau protein .

HY-B0949A

Protriptyline	Cholinesterase (ChE) Amyloid-β	Neurological Disease
Protriptyline is a potent antidepressant agent. Protriptyline inhibits AChE activity with IC₅₀ value of 0.06 mM and inhibits Aβ Self-Assembly. Protriptyline can be used for depression and Alzheimers disease .

HY-P4808

PHF6	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P5681

Human α-Defensin 6	Bacterial	Infection Inflammation/Immunology
Human α-Defensin 6, a 32-residue cysteine-rich peptide, can inhibit bacterial invasion and contribute to the mucosal immunity. Human α-Defensin 6 forms ordered self-assembly fibrils and nanonets that surround and entangle bacteria after stochastic binding to bacterial surface proteins. Human α-Defensin 6 also inhibits C. albicans biofilm formation .

HY-163201

TMV-IN-7	TMV	Infection
TMV-IN-7 (compound G2) is a potent inhibitor of tobacco mosaic virus (TMV). TMV-IN-7 exhibits strong hydrophobic interactions to obstructing the virus’s self-assembly .

HY-W099571

Lithium stearate Stearic acid lithium; Lithium octadecanoate	Others	Others
Lithium stearate (Stearic acid (lithium)) is a compound that forms vesicles in reaction with silver nitrate, thereby changing the reaction kinetics of the nucleation and self-assembly process of silver stearate. It has the activity that even in the presence of excess silver nitrate, only about 80% can be converted into silver stearate and the residual lithium stearate will inhibit the growth process of silver stearate crystals, thereby producing silver stearate crystals that are much smaller than those obtained from sodium stearate, providing an opportunity to further control the self-assembly and crystal growth of silver stearate.

HY-145785

ADH-6	MDM-2/p53 Apoptosis	Cancer
ADH-6 is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 has the potential for the research of cancer diseases[1].

HY-145785A

ADH-6 TFA	MDM-2/p53 Apoptosis	Cancer
ADH-6 TFA is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential for the research of cancer diseases .

HY-W440699

Cholesterol-PEG-acid (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-acid (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 3400) can be used in drug delivery research .

HY-W440700

Cholesterol-PEG-acid (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-acid (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 5000) can be used in drug delivery research .

HY-W591891

Cholesterol-PEG-acid (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-acid (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-acid (MW 1000) can be used in drug delivery research .

HY-W440704

Cholesterol-PEG-NHS (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-NHS (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 5000) can be used in drug delivery research .

HY-W440689

Cholesterol-PEG-amine (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-amine (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 1000) can be used in drug delivery research .

HY-W440691

Cholesterol-PEG-amine (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-amine (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 3400) can be used in drug delivery research .

HY-W440692

Cholesterol-PEG-amine (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-amine (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-amine (MW 5000) can be used in drug delivery research .

HY-W440693

Cholesterol-PEG-azide (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-azide (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 1000) can be used in drug delivery research .

HY-W440695

Cholesterol-PEG-azide (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-azide (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 3400) can be used in drug delivery research .

HY-W440696

Cholesterol-PEG-azide (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-azide (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-azide (MW 5000) can be used in drug delivery research .

HY-W440697

Cholesterol-PEG-NHS (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-NHS (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 1000) can be used in drug delivery research .

HY-W440702

Cholesterol-PEG-NHS (MW 2000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-NHS (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 2000) can be used in drug delivery research .

HY-W440703

Cholesterol-PEG-NHS (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-NHS (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-NHS (MW 3400) can be used in drug delivery research .

HY-W440705

Cholesterol-PEG-alcohol (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-alcohol (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 1000) can be used in drug delivery research .

HY-W440707

Cholesterol-PEG-alcohol (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-alcohol (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 3400) can be used in drug delivery research .

HY-W440708

Cholesterol-PEG-alcohol (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-alcohol (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 5000) can be used in drug delivery research .

HY-W440709

Cholesterol-PEG-alcohol (MW 10000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-alcohol (MW 10000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-alcohol (MW 10000) can be used in drug delivery research .

HY-W440710

Cholesterol-PEG-Biotin (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Biotin (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 1000) can be used in drug delivery research .

HY-W440712

Cholesterol-PEG-Biotin (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Biotin (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 3400) can be used in drug delivery research .

HY-W440713

Cholesterol-PEG-Biotin (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Biotin (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Biotin (MW 5000) can be used in drug delivery research .

HY-W440714

Cholesterol-PEG-Folate (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Folate (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 1000) can be used in drug delivery research .

HY-W440716

Cholesterol-PEG-Folate (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Folate (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 3400) can be used in drug delivery research .

HY-W440717

Cholesterol-PEG-Folate (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Folate (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 5000) can be used in drug delivery research .

HY-W440718

Cholesterol-PEG-Mal (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Mal (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 1000) can be used in drug delivery research .

HY-W440720

Cholesterol-PEG-Mal (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Mal (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 3400) can be used in drug delivery research .

HY-W440721

Cholesterol-PEG-Mal (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Mal (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Mal (MW 5000) can be used in drug delivery research .

HY-W440723

Cholesterol-PEG-Thiol (MW 2000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Thiol (MW 2000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Thiol (MW 2000) can be used in drug delivery research .

HY-W440725

Cholesterol-PEG-Thiol (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Thiol (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Thiol (MW 5000) can be used in drug delivery research .

HY-W440726

Cholesterol-PEG-Vinylsulfone (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Vinylsulfone (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 1000) can be used in drug delivery research .

HY-W440728

Cholesterol-PEG-Vinylsulfone (MW 3400)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Vinylsulfone (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 3400) can be used in drug delivery research .

HY-W440729

Cholesterol-PEG-Vinylsulfone (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-Vinylsulfone (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Vinylsulfone (MW 5000) can be used in drug delivery research .

HY-W591912

Cholesterol-PEG-methoxy (MW 1000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-methoxy (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-methoxy (MW 1000) can be used in drug delivery research .

HY-W591914

Cholesterol-PEG-methoxy (MW 5000)	Biochemical Assay Reagents	Others
Cholesterol-PEG-methoxy (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-methoxy (MW 5000) can be used in drug delivery research .

HY-154971

Ara-SH	Apoptosis	Cancer
Ara-SH is a Cytarabine mercaptopropionic acid-substituted derivative. Ara-SH is used as the trigger to fabricate a smart Cytarabine and Venetoclax-coloaded nanoparticle (AV-NP) through self-assembly. Ara-SH exhibits remarkable synergistic antileukemia effects in vitro and in vivo .

HY-W751932

Carboxy-EG6-undecanethiol	Biochemical Assay Reagents	Others
Carboxy-EG6-undecanethiol is an alkanethiol that suitable for self-assembly a gold thin-film substrate. Carboxy-EG6-undecanethiol can selectively capture HbA1c in sample by covalent coupling of 3-aminophenyl boronic acid (3-APBA) .

HY-163999

TMV-IN-12	TMV	Infection
TMV-IN-12 (compound 4) is an inhibitor of tobacco mosaic virus (TMV) with antifungal properties. TMV-IN-12 effectively prevents TMV particle aggregation and self-assembly of TMV capsid protein (TMV-CP) (Kd=0.142 μM), preventing TMV from infecting tobacco plants .

HY-149763

Aβ42 agonist-1	Amyloid-β	Neurological Disease
Aβ42 agonist-1 (compound 7a) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-1 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-1 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells .

HY-149764

Aβ42 agonist-2	Amyloid-β	Neurological Disease
Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells .

HY-B0949

Protriptyline hydrochloride 3 Publications Verification	Cholinesterase (ChE)	Neurological Disease
Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD.

Cat. No.	Product Name	Target	Research Area

HY-P4147

Ac-IHIHIQI-NH2	Peptides	Others
Ac-IHIHIQI-NH2 is a fibril-forming heptapeptide with high catalytic activity to laccase mimics. Ac-IHIHIQI-NH2 exhibits selectivity for hydrophobic p-nitrophenyl (ONp) ester substrates in the process of self-assembly .

HY-P1449

Boc-Gly-Gly-Phe-Gly-OH	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-P1449A

Boc-Gly-Gly-Phe-Gly-OH TFA	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-P4808A

PHF6 TFA	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P10494

FEFEFKFK	Peptides	Neurological Disease
FEFEFKFK is an octapeptide that self-assembles into fibrillar structures. FEFEFKFK is able to form gels at concentrations greater than about 7 mg/mL. The self-assembly and gelation properties of FEFEFKFK help to understand the mechanism of amyloid fibril formation in protein misfolding diseases such as Alzheimer's disease and Parkinson's disease .

HY-P4808

PHF6	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P5681

Human α-Defensin 6	Bacterial	Infection Inflammation/Immunology
Human α-Defensin 6, a 32-residue cysteine-rich peptide, can inhibit bacterial invasion and contribute to the mucosal immunity. Human α-Defensin 6 forms ordered self-assembly fibrils and nanonets that surround and entangle bacteria after stochastic binding to bacterial surface proteins. Human α-Defensin 6 also inhibits C. albicans biofilm formation .

HY-P10453

Myr5A peptide	Peptides	Others
Myr5A peptide is an acylated peptide composed of apolipoprotein A1 (ApoA1) analog peptide 5A peptide coupled to the saturated fatty acid myristate. Myr5A peptide self-assembled into lipid nanostructures can be used to encapsulate anthracycline Doxorubicin (HY-15142A) and Valrubicin (HY-13772) for compound release studies in vitro .

Cat. No.	Product Name		Classification

HY-167071

PLLA-azide (MW 5000)		Azide
PLLA-azide (MW 5000) is a polylactic acid derivative that can self-assemble in water. PLLA-azide (MW 5000) can be used in drug delivery research .

HY-167115

PLLA-azide (MW 20000)		Azide
PLLA-azide (MW 20000) is a polylactic acid derivative that can self-assemble in water. PLLA-azide (MW 20000) can be used in drug delivery research .

HY-167117

PLLA-azide (MW 10000)		Azide
PLLA-azide (MW 10000) is a polylactic acid derivative that can self-assemble in water. PLLA-azide (MW 10000) can be used in drug delivery research .

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self-assembly

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Click Chemistry

Natural
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