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viral translation

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115805

    Virus Protease Infection
    YKL-04-085 is potent inhibitors of viral translation, with an IC90 of 0.555 μM for DENV2. YKL-04-085 is devoid of any kinase activity .
    YKL-04-085
  • HY-169123

    Eukaryotic Initiation Factor (eIF) Infection Cancer
    DMDA-PatA is a small-molecule eIF4A inhibitor that represses translation in an mRNA-selective and ATP-independent manner by clamping eIF4A, a DEAD-box RNA binding protein, onto GNG motifs. DMDA-PatA is promising for research of cancers and viral infections .
    DMDA-PatA
  • HY-149362

    SARS-CoV Infection
    MTase-IN-1 (compound 26) is a potent and selective inhibitor of coronavirus nsp14 N7-methyltransferases, with an IC50 of 0.72 nM. MTase-IN-1 impairs viral RNA translation and immune evasion .
    MTase-IN-1
  • HY-125629

    Others Others
    Primordazine B is a small molecule compound identified by chemical screening in zebrafish embryos with the activity of selectively destroying Primordial Germ Cells (PGCs). Primordazine B inhibits a process called Poly(A)-tail Independent Non-canonical Translation (PAINT) without inhibition of polyadenylate tail dependent typical translation (PAT). Primordazine B can be used to study translational control of cells in specific physiological or pathological states, such as gene expression regulation during cell dormancy, viral infection, or stress conditions .
    Primordazine B

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