Clomipramine-d₃ (Synonyms: Chlorimipramine-d₃; G-34586-d₃; NSC-169865-d₃)

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Clomipramine-d₃ is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].

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Clomipramine-d<sub>3</sub> Chemical Structure

Clomipramine-d₃ Chemical Structure

CAS No. : 136765-29-2

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Dopamine Receptor D₁ Receptor D₂ Receptor D₃ Receptor D₄ Receptor D₅ Receptor

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Description	Clomipramine-d₃ is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].
Molecular Weight	317.87
Formula	C₁₉H₂₀D₃ClN₂
CAS No.	136765-29-2
Unlabeled CAS	303-49-1
SMILES	ClC1=CC2=C(C=C1)CCC3=C(C=CC=C3)N2CCCN(C([2H])([2H])[2H])C
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (272 KB) Handling Instructions (2659 KB)
References	[1]. McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53. [Content Brief] [2]. Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22. [Content Brief]

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Clomipramine-d₃136765-29-2Chlorimipramine-d₃G-34586-d₃NSC-169865-d₃Serotonin TransporterDopamine Receptor5-HTTSERTSLC6A4Inhibitorinhibitorinhibit

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Clomipramine-d3 (Synonyms: Chlorimipramine-d3; G-34586-d3; NSC-169865-d3)

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