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Results for "

ADCP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CD38 (1) CTLA-4 (1) Immune Checkpoint (1) PD-1/PD-L1 (1) Radionuclide-Drug Conjugates (RDCs) (1) TNF Receptor (1)
By Research Areas:	Cancer (4) Inflammation/Immunology (2)

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Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99117

Cadonilimab AK104	PD-1/PD-L1 CTLA-4 Immune Checkpoint	Inflammation/Immunology Cancer
Cadonilimab (AK104) is a humanized tetravalent IgG1 bispecific antibody targeting PD1/CTLA4. Cadonilimab blocks both PD-1 and CTLA-4 pathways, thereby relieving their corresponding immunosuppressive effects and reversing tumor specific T cell exhaustion. Cadonilimab significantly downregulates Fc-mediated effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), complement dependent cytotoxicity (CDC). Cadonilimab can be used for research of metastatic cervical cancer, as well as other malignancies such as gastric cancer, GEJ adenocarcinoma and non-small cell lung cancer (NSCLC) .

HY-P99015

Dacetuzumab	TNF Receptor	Cancer
Dacetuzumab (SGN-40) is a humanized IgG1, anti-CD40 monoclonal antibody with anti-lymphoma activity. Dacetuzumab kills tumor cells via immune effector functions (antibody-dependent cellular cytotoxicity and phagocytosis [ADCC/ADCP]). Dacetuzumab ((SGN-40) can be used for multiple myeloma research .

HY-P9976A

Isatuximab (anti-CD38) 1 Publications Verification	CD38	Cancer
Isatuximab (anti-CD38) is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38.Isatuximab induces tumor cell killing via fragment crystallizable (Fc)-dependent or Fc-independent mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC) .

HY-P9983

Lintuzumab HuM-195	Others Radionuclide-Drug Conjugates (RDCs)	Inflammation/Immunology
Lintuzumab (HUM-195) is an anti-CD33 humanized monoclonal antibody. Lintuzumab reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells. Lintuzumab promotes tumor cell killing through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities against MDR? and MDR+ AML cell lines and primary AML patient samples. Lintuzumab enhances survival and reduces tumor burden in mice .

Cat. No.	Product Name	Target	Research Area

HY-P99117

Cadonilimab AK104	PD-1/PD-L1 CTLA-4 Immune Checkpoint	Inflammation/Immunology Cancer
Cadonilimab (AK104) is a humanized tetravalent IgG1 bispecific antibody targeting PD1/CTLA4. Cadonilimab blocks both PD-1 and CTLA-4 pathways, thereby relieving their corresponding immunosuppressive effects and reversing tumor specific T cell exhaustion. Cadonilimab significantly downregulates Fc-mediated effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), complement dependent cytotoxicity (CDC). Cadonilimab can be used for research of metastatic cervical cancer, as well as other malignancies such as gastric cancer, GEJ adenocarcinoma and non-small cell lung cancer (NSCLC) .

HY-P99015

Dacetuzumab	TNF Receptor	Cancer
Dacetuzumab (SGN-40) is a humanized IgG1, anti-CD40 monoclonal antibody with anti-lymphoma activity. Dacetuzumab kills tumor cells via immune effector functions (antibody-dependent cellular cytotoxicity and phagocytosis [ADCC/ADCP]). Dacetuzumab ((SGN-40) can be used for multiple myeloma research .

HY-P99381

XmAb 5592	Inhibitory Antibodies	Cancer
XmAb 5592 is a humanized, Fc-engineered anti-HM1.24 antibody with enhanced binding to FcγRIIIa and FcγRIIa receptors, augments HM1.24-specific multiple myeloma (MM) cells lysis in vitro via antibody-dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP) .

HY-P9976A

Isatuximab (anti-CD38) 1 Publications Verification	CD38	Cancer
Isatuximab (anti-CD38) is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38.Isatuximab induces tumor cell killing via fragment crystallizable (Fc)-dependent or Fc-independent mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC) .

HY-P9983

Lintuzumab HuM-195	Inhibitory Antibodies Radionuclide-Drug Conjugates (RDCs)	Inflammation/Immunology
Lintuzumab (HUM-195) is an anti-CD33 humanized monoclonal antibody. Lintuzumab reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells. Lintuzumab promotes tumor cell killing through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities against MDR? and MDR+ AML cell lines and primary AML patient samples. Lintuzumab enhances survival and reduces tumor burden in mice .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P99117

Cadonilimab AK104	Classification of Application Fields Disease Research Fields Cancer	PD-1/PD-L1 CTLA-4 Immune Checkpoint
Cadonilimab (AK104) is a humanized tetravalent IgG1 bispecific antibody targeting PD1/CTLA4. Cadonilimab blocks both PD-1 and CTLA-4 pathways, thereby relieving their corresponding immunosuppressive effects and reversing tumor specific T cell exhaustion. Cadonilimab significantly downregulates Fc-mediated effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), complement dependent cytotoxicity (CDC). Cadonilimab can be used for research of metastatic cervical cancer, as well as other malignancies such as gastric cancer, GEJ adenocarcinoma and non-small cell lung cancer (NSCLC) .

HY-P99015

Dacetuzumab	Classification of Application Fields Disease Research Fields Cancer	TNF Receptor
Dacetuzumab (SGN-40) is a humanized IgG1, anti-CD40 monoclonal antibody with anti-lymphoma activity. Dacetuzumab kills tumor cells via immune effector functions (antibody-dependent cellular cytotoxicity and phagocytosis [ADCC/ADCP]). Dacetuzumab ((SGN-40) can be used for multiple myeloma research .

Species:	Human (3) Mouse (2) Cynomolgus (3)
Tag:	His (3) Tag Free (2) Fc (3)
Source:	HEK293 (8)

Cat. No.	Compare	Product Name	Species	Source

HY-P72975

	CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293) Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with tag free. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293) is 738 a.a., with molecular weight of ~95 kDa.

HY-P72976

	CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc) Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, Fc) is 738 a.a., with molecular weight of 120-130 kDa.

HY-P75428

	CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, His) Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Mouse	HEK293
	CD26/dipeptidyl peptidase 4 is a key cell surface receptor for T cell activation. It binds to ADA, CAV1, IGF2R and PTPRC to promote T cell proliferation and NF-kappa-B activation. CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, His) is 732 a.a., with molecular weight of ~85.9 kDa.

HY-P75429

	CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, Fc) Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Mouse	HEK293
	CD26/dipeptidyl peptidase 4 is a key cell surface receptor for T cell activation. It binds to ADA, CAV1, IGF2R and PTPRC to promote T cell proliferation and NF-kappa-B activation. CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Mouse (HEK293, Fc) is 732 a.a., with molecular weight of ~122.5 kDa.

HY-P76876

	CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, His) Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, His) is 733 a.a., with molecular weight of 100-130 KDa.

HY-P76877

	CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, Fc) Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293, Fc) is 733 a.a., with molecular weight of ~113 kDa.

HY-P70017

	CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, His) rHuDipeptidyl peptidase 4/CD26, His; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26	Human	HEK293
	The CD26/dipeptidyl peptidase 4 protein is a cell surface glycoprotein receptor that induces T cell proliferation and NF-kappa-B activation. CD26 also works with FAP to promote pericellular proteolysis, endothelial cell migration, and invasion of the extracellular matrix. CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, His) is the recombinant human-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Human (HEK293, His) is 738 a.a., with molecular weight of 86-130 kDa.

HY-P76875

	CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293) Dipeptidyl peptidase 4; ADABP; ADCP-2; DPP IV; TP103; CD26; DPP4	Cynomolgus	HEK293
	CD26/Dipeptidyl Peptidase 4 Protein is a serine membrane anchored exopeptidase, belonging to dipeptidyl peptidase (DPP) family. CD26/Dipeptidyl Peptidase 4 Protein is widely expressed in a variety of tissues and many cells. CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293) is the recombinant cynomolgus-derived CD26/Dipeptidyl Peptidase 4 protein, expressed by HEK293 , with tag free. The total length of CD26/Dipeptidyl Peptidase 4 Protein, Cynomolgus (HEK293) is 733 a.a., with molecular weight of 92-102 kDa.

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HY-P81529

	DPP4/CD26 Antibody (YA1274) ADCP2, CD26; DPP4; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2 (ADCP-2); Dipeptidyl peptidase IV (DPP IV); T-cell activation antigen CD26; TP103	IHC-P	Human
	DPP4/CD26 Antibody (YA1274) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1274), targeting DPP4/CD26. DPP4/CD26 Antibody (YA1274) can be used for IHC-P experiment in human background.

HY-P82766

	CD26 Antibody (YA2511) DPP4; ADCP2; CD26; Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26; TP103; CD26	WB	Human, Mouse, Rat
	CD26 Antibody (YA2511) is a biotin-conjugated non-conjugated IgG antibody, targeting CD26, with a predicted molecular weight of 88 kDa (observed band size: 110 kDa). CD26 Antibody (YA2511) can be used for WB experiment in human, mouse, rat background.

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ADCP

Inhibitors & Agonists

Inhibitory Antibodies

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