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Results for "

Bronchospasm

" in MedChemExpress (MCE) Product Catalog:

25

Inhibitors & Agonists

2

Peptides

1

Natural
Products

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118545A
    Butamirate citrate

    		Biochemical Assay Reagents Inflammation/Immunology
    Butamirate citrate is an orally active cough suppressant that acts centrally through the receptors in the brainstem. Butamirate citrate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect .
    Butamirate citrate
  • HY-B0004
    Doxofylline

    		Adenosine Receptor Phosphodiesterase (PDE) Reactive Oxygen Species Inflammation/Immunology
    Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways (NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm .
    Doxofylline
  • HY-N0283
    Diacerein
    2 Publications Verification

    Diacerhein; Diacetylrhein

    		 Interleukin Related Calcium Channel Inflammation/Immunology
    Diacerein (Diacerhein), an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling. Diacerein is an anti-inflammatory and anti-rheumatic drug. Diacerein can relieve bronchospasm and control airway inflammation in asthmatic mice. Diacerein has the potential for slow acting drug in osteoarthritis (SYSADOA) research .
    Diacerein
  • HY-120755
    LY290324

    		Leukotriene Receptor Inflammation/Immunology
    LY290324 is a potent and orally active leukotriene D4 (LTD4) antagonist. LY290324 reduces LTC4, LTD4 and LTE4 (HY-113465)-induced bronchospasm. LY290324 has the potential for the research of antigen-induced bronchospasm .
    LY290324
  • HY-121185
    Hexoprenaline

    		Adrenergic Receptor Infection Inflammation/Immunology
    Hexoprenaline is an orally active and selective β-adrenergic receptor agonist that dilates the bronchi. Hexoprenaline can be used in the study of bronchospasm, including asthma, bronchitis, and emphysema .
    Hexoprenaline
  • HY-118545
    Butamirate

    		Biochemical Assay Reagents Inflammation/Immunology
    Butamirate is an orally active cough suppressant that acts centrally through the receptors in the brainstem. Butamirate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect .
    Butamirate
  • HY-109006
    Ilmetropium iodide

    		mAChR Neurological Disease
    Ilmetropium iodide is an anticholinergic agent. Ilmetropium iodide selectively blocks M-cholinergic receptors of bronchial muscle, reduces or prevents bronchoconstrictor response associated with both cholinergic stimulation, as well as the impact of the factors that provoke bronchospasm. Strength and selectivity of ilmetropium iodide action substantially exceeds Atropine sulfate (HY-B1205A) and Ipratropium bromide (HY-B0241) .
    Ilmetropium iodide
  • HY-B0004R
    Doxofylline (Standard)

    		Adenosine Receptor Phosphodiesterase (PDE) Reactive Oxygen Species Inflammation/Immunology
    Doxofylline (Standard) is the analytical standard of Doxofylline. This product is intended for research and analytical applications. Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways (NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm .
    Doxofylline (Standard)
  • HY-129546
    Eprozinol hydrochloride

    		Endogenous Metabolite Inflammation/Immunology
    Eprozinol hydrochloride is a compound with antibronchoconstrictor activity. Eprozinol hydrochloride can be used in the study of bronchospasm .
    Eprozinol hydrochloride
  • HY-118376
    Nestifylline

    		Others Others
    Nestifylline is a biochemical reagent. Nestifylline can be used to study respiratory diseases such as bronchospasm .
    Nestifylline
  • HY-B1037S
    Salbutamol-d3

    Albuterol-d3; AH-3365-d3

    		 Adrenergic Receptor Neurological Disease Endocrinology
    Salbutamol-d3 is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).
    Salbutamol-d3
  • HY-B1037S2
    Salbutamol-d9

    Albuterol-d9; AH-3365-d9

    		 Isotope-Labeled Compounds Adrenergic Receptor Neurological Disease Endocrinology
    Salbutamol-d9 is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).
    Salbutamol-d9
  • HY-B1037S3
    Salbutamol-d9 acetate

    Albuterol-d9 acetate; AH-3365-d9 acetate

    		 Adrenergic Receptor Endocrinology
    Salbutamol-d9 (acetate) is the deuterium labeled Salbutamol[1]. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).
    Salbutamol-d9 acetate
  • HY-116051A
    16,16-Dimethylprostaglandin F2β

    16,16-Dimethyl-PGF2β

    		 Others Cardiovascular Disease
    16,16-Dimethylprostaglandin F2β (16,16-Dimethyl-PGF2β) is an analog of PGF2β (HY-12956B), which is an irratant, but prevents the aspecifically induced bronchospasm .
    16,16-Dimethylprostaglandin F2β
  • HY-B0976
    Fenoterol

    Th-1165; Phenoterol

    		 Adrenergic Receptor Inflammation/Immunology Endocrinology
    Fenoterol (Th-1165), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research .
    Fenoterol
  • HY-164650
    Pirodomast

    Sch 37224

    		 Leukotriene Receptor Inflammation/Immunology
    Pirodomast (Sch 37224) is a leukotriene formation inhibitor. Pirodomast inhibits LTD4 andthromboxane B2 release by anaphylactic guinea pig lung with the IC50 values of 3.9 and 1.9 μM, respectively. Pirodomast can be used for study of asthma .
    Pirodomast
  • HY-B0976A
    Fenoterol hydrobromide

    Th-1165a; Phenoterol hydrobromide

    		 Adrenergic Receptor Inflammation/Immunology Endocrinology
    Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research .
    Fenoterol hydrobromide
  • HY-B1037
    Salbutamol
    4 Publications Verification

    Albuterol; AH-3365

    		 Adrenergic Receptor ERK Inflammation/Immunology Cancer
    Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) .
    Salbutamol
  • HY-B1037B
    Salbutamol adipate

    Albuterol adipate; AH-3365 adipate

    		 Adrenergic Receptor ERK Inflammation/Immunology Cancer
    Salbutamol (Albuterol) adipate is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol adipate promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol adipate is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) .
    Salbutamol adipate
  • HY-B0976AR
    Fenoterol hydrobromide (Standard)

    Th-1165a (Standard); Phenoterol hydrobromide (Standard)

    		 Adrenergic Receptor Inflammation/Immunology Endocrinology
    Fenoterol (hydrobromide) (Standard) is the analytical standard of Fenoterol (hydrobromide). This product is intended for research and analytical applications. Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research .
    Fenoterol hydrobromide (Standard)
  • HY-B0976AS
    Fenoterol-d6 hydrobromide

    		Adrenergic Receptor Inflammation/Immunology Endocrinology
    Fenoterol-d6 (hydrobromide) (Th-1165a-d6) is the deuterium labeled Fenoterol hydrobromide. Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research[1][2].
    Fenoterol-d6 hydrobromide
  • HY-B1037R
    Salbutamol (Standard)

    Albuterol (Standard); AH-3365 (Standard)

    		 Adrenergic Receptor ERK Inflammation/Immunology Cancer
    Salbutamol (Standard) is the analytical standard of Salbutamol. This product is intended for research and analytical applications. Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD) .
    Salbutamol (Standard)
  • HY-117811
    (R,R)-MK 287

    L-680574

    		 Others Others
    (R,R)-MK 287 is a tetrahydrofuran derivative that effectively inhibits the binding of [3H]C18-PAF to human platelets, polymorphonuclear leukocytes (PMNs), and lung membranes with K1 values of 6.1 ± 1.5, 3.2 ± 0.7, and 5.49 ± 2.3 nM, respectively. The inhibition is stereospecific and competitive. Its racemate, L-668,750, is less potent, and its enantiomer, L-680574, is only 1/20 as potent as MK 287. MK 287 inhibits the binding of [3H]C18-PAF to human PMN membranes, reducing the affinity of the radioligand without changing the number of receptor sites. The binding of other radioligands (e.g., LTB4, LTC4, C5a, FMLP) to their specific receptors is unchanged at 1-10 microM MK 287. [3H]MK 287 binds to human platelet and PMN membranes with KD values of 2.1 ± 0.6 and 2.9 ± 1.2 nM. When tested on isolated human cells, MK 287 potently and selectively inhibits PAF-induced platelet aggregation (ED50 = 56 ± 38 nM or ED50 = 1.5 ± 0.5 nM for gel-filtered platelets) and elastase release from PMNs (ED50 = 4.4 ± 2.6 nM). In vivo studies, MK 287 inhibited PAF-induced lethality in mice (ED50 = 0.8 mg/kg oral) and PAF-induced bronchospasm in guinea pigs (ED50 = 0.18 mg/kg intraduodenally and 0.19 mg/kg intravenously). The inhibition of PAF-induced bronchospasm was accompanied by a rightward shift in the concentration-response curve for PAF-induced platelet aggregation measured in vitro.
    (R,R)-MK 287
  • HY-P0012
    Aviptadil
    1 Publications Verification

    Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine)

    		 SARS-CoV Infection Inflammation/Immunology
    Aviptadil is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al .
    Aviptadil
  • HY-P0012A
    Aviptadil acetate
    1 Publications Verification

    Vasoactive Intestinal Peptide acetate salt (human, rat, mouse, rabbit, canine, porcine)

    		 SARS-CoV Infection Inflammation/Immunology
    Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al .
    Aviptadil acetate

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