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CDH1

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By Targets:	Antibiotic (1) APC (2) Apoptosis (1) Autophagy (1) Bacterial (1) Endogenous Metabolite (1) Mitophagy (1) Proteasome (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (5) Infection (1) Inflammation/Immunology (2)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

6

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Natural
Products

7

Recombinant Proteins

2

Antibodies

1

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

TAME	APC	Cancer
TAME is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC), which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest. TAME is not cell permeable ^[1] .

TAME hydrochloride	APC	Cancer
TAME hydrochloride is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC), which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest. TAME hydrochloride is not cell permeable ^[1] .

Celastrol 35+ Cited Publications Tripterine; Tripterin	Proteasome Autophagy Mitophagy Apoptosis Endogenous Metabolite Antibiotic Bacterial	Infection Inflammation/Immunology Cancer
Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC₅₀ of 2.5 μM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH .

CDH1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CDH1 Human Pre-designed siRNA Set A contains three designed siRNAs for CDH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CDH1 Human Pre-designed siRNA Set A CDH1 Human Pre-designed siRNA Set A

SLEC-11	Others	Cancer
SLEC-11 acts as a potential synthetic lethal lead for the research of gastric cancer. AL-GDa62 shows EC₅₀ of 12.2 μM and 8.2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1 ^-/- ^[1].

AL-GDa62	Others	Cancer
AL-GDa62 acts as a potential synthetic lethal lead for the research of gastric cancer. AL-GDa62 shows EC₅₀ of 3.2 μM and 2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1 ^-/- ^[1].

Cat. No.	Product Name	Target	Research Area

*Anti-CDH1/E-cadherin/CD324 Antibody*	Inhibitory Antibodies	Inflammation/Immunology
Anti-CDH1/E-cadherin/CD324 Antibody is a humanized antibody expressed in CHO, targeting *CDH1/E-cadherin/CD324. The Anti-CDH1/E-cadherin/CD324 Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.6 kDa. The isotype control for Anti-CDH1*/E-cadherin/CD324 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

Species:	Human (3) Rat (2) Mouse (1) Cynomolgus (1)
Tag:	His (4) Fc (3)
Source:	HEK293 (7)

Cat. No.	Compare	Product Name	Species	Source

	Cadherin-1/CD324 Protein, Human (HEK293, His) rHuCadherin-1/CD324, His; Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324	Human	HEK293
	Cadherin-1/CD324 Protein, Human (HEK293, His) is a recombinant human E-cadherin produced in HEK293 cells, with His tag. Cadherin-1/CD324/E-cadherin is one of the most important molecules in cell-cell adhesion in epithelial tissues.

	Cadherin-1/CD324 Protein, Rat (HEK293, His) Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324	Rat	HEK293
	Cadherin-1/CD324 protein, a calcium-dependent adhesion molecule, mediates cell processes. It interacts homophilically with other cadherin molecules, sorting and organizing cell types. CDH1 regulates adhesion, mobility, and proliferation of epithelial cells. It serves as an integrin ligand, suppressing invasion and promoting non-amyloidogenic degradation. CDH1 inhibits APP C99 and C83 production. Cadherin-1/CD324 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-His labeled tag.

	Cadherin-1/CD324 Protein, Rat (HEK293, Fc) Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324	Rat	HEK293
	Cadherin-1/CD324 protein, a calcium-dependent adhesion molecule, mediates cell processes. It interacts homophilically with other cadherin molecules, sorting and organizing cell types. CDH1 regulates adhesion, mobility, and proliferation of epithelial cells. It serves as an integrin ligand, suppressing invasion and promoting non-amyloidogenic degradation. CDH1 inhibits APP C99 and C83 production. Cadherin-1/CD324 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Cadherin-1/CD324 protein, expressed by HEK293, with C-hFc labeled tag. The total length of Cadherin-1/CD324 Protein, Rat (HEK293, Fc) is 690 a.a., with molecular weight of 95-130 kDa.

	Cadherin-1/CD324 Protein, Human (HEK293, Fc) Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324	Human	HEK293
	The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag.

	Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324	Human	HEK293
	The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) is 685 a.a., with molecular weight of ~87.1 KDa.

	Cadherin-1/CD324 Protein, Mouse (HEK293, C-His) Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324	Mouse	HEK293
	Cadherin-1/CD324 is a calcium-dependent cell adhesion protein that orchestrates homogeneous interactions, promoting cell cohesion and potential cell type sorting. CDH1 regulates epithelial cell adhesion, mobility, and proliferation and acts as an invasive suppressor. Cadherin-1/CD324 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-6*His labeled tag.

	Cadherin-1/CD324 Protein, Cynomolgus (HEK293, His) Cadherin-1; Cadherin1; E-Cadherin; E Cadherin; Epithelial cadherin; CDH1; CD324; Arc-1; CAD1; ECAD; E-CAD; LCAM; UVO; L-CAM	Cynomolgus	HEK293
	Cadherin-1/CD324 Protein, a calcium-dependent receptor on myeloid cells, binds to carbohydrates on neutrophils and monocytes. It facilitates interaction between activated endothelial cells or platelets with leukocytes. It recognizes sialyl-Lewis X as its ligand. Through interaction with SELPLG, it mediates rapid leukocyte rolling in early inflammation. Cadherin-1/CD324 Protein also interacts with SNX17 and facilitates neutrophil adhesion and rolling, depending on sialyl-Lewis X epitope and tyrosine sulfation. Cadherin-1/CD324 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-1/CD324 Protein, Cynomolgus (HEK293, His) is 554 a.a., with molecular weight of 68-78 kDa.

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Cat. No.	Compare	Product Name	Application	Reactivity

	E Cadherin Antibody CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324	WB, IHC-P, IHC-F, ICC/IF, ELISA	Human, Mouse, Rat
	E Cadherin Antibody is a rabbit-derived non-conjugated IgG antibody , targeting E Cadherin, with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). E Cadherin Antibody can be used for WB, IHC-P, IHC-F, ICC/IF, ELISA experiment in human, mouse, rat background.

	Phospho-E Cadherin (Ser838/Ser840) Antibody (YA2579) CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324	WB, IHC-P, IP	Human, Mouse
	Phospho-E Cadherin (Ser838/Ser840) Antibody (YA2579) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2579), targeting Phospho-E Cadherin (Ser838/Ser840), with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). Phospho-E Cadherin (Ser838/Ser840) Antibody (YA2579) can be used for WB, IHC-P, IP experiment in human, mouse background.

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