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  2. Primary Antibodies
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  4. E Cadherin Antibody

E Cadherin Antibody

Cat. No.: HY-P81271
COA User Guide for Antibodies

E Cadherin Antibody is a rabbit-derived non-conjugated IgG antibody , targeting E Cadherin, with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). E Cadherin Antibody can be used for WB, IHC-P, IHC-F, ICC/IF, ELISA experiment in human, mouse, rat background.

For research use only. We do not sell to patients.

Size Price Stock Quantity
10 μL $70 In-stock
50 μL $185 In-stock
100 μL $300 In-stock
250 μL   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

E Cadherin Antibody is a rabbit-derived non-conjugated IgG antibody , targeting E Cadherin, with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). E Cadherin Antibody can be used for WB, IHC-P, IHC-F, ICC/IF, ELISA experiment in human, mouse, rat background.

Background

The related gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to related generate the mature glycoprotein. The calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in The related gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of The related gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of The protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. The related gene is present in a related gene cluster with other members of the cadherin family on chromosome 16.

Gene ID

999

Synonyms
CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324
Molecular Weight

Predicted band size: 97 kDa; Observed band size: 135 kDa

Purity

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Research Field

Signal Transduction

Product Categories

Primary Antibody; Rabbit Polyclonal Antibody

Clonality

Polyclonal

Host

Rabbit

Reactivity

Human, Mouse, Rat

SwissProt ID

P12830

Dilution Ratio

WB: 1/500-1/1000; IHC: 1/50-1/100; IF: 1/50-1/200; ELISA: 1/10000

Application

WB, IHC-P, IHC-F, ICC/IF, ELISA

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Isotype

IgG

Sensitivity

Endogenous

Immunogen

The antiserum was produced against synthesized peptide derived from human Cadherin.

Documentation

E Cadherin Antibody Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
E Cadherin Antibody
Cat. No.:
HY-P81271
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