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Results for "

CTX

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Aminopeptidase (1) Antibiotic (5) Bacterial (10) Beta-lactamase (8) CCR (4) CDK (1) Drug Metabolite (1) E1/E2/E3 Enzyme (1) Histone Acetyltransferase (1) Interleukin Related (1) MDM-2/p53 (1) Penicillin-binding protein (PBP) (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (2) Endocrinology (2) Infection (10) Inflammation/Immunology (6) Metabolic Disease (3) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99178

CTX-471	Interleukin Related	Inflammation/Immunology Cancer
CTX-471 is a fully human monoclonal antibody of CD137. CTX-471 has bind affinity for recombinant human, cynomolgus macaque CD137 and mouse CD137 with K_d values of 50 nM, 61 nM and 748 nM, respectively. CTX-471 can be used for the research of immunomodulation and cancer .

HY-136473

CTX-0124143	Others	Cancer
CTX-0124143 is a KAT6A inhibitor with a sulfonyl hydrazine skeleton .

HY-15985

CTX-0294885 3 Publications Verification	Akt	Metabolic Disease Inflammation/Immunology Cancer
CTX-0294885 is a broad spectrum kinase inhibitor that can capture 235 kinases from MDA-MB-231 cells, and can capture all members of the AKT family. CTX-0294885 is a powerful reagent for analysis of kinome signaling networks that can be used for the research of diseases like inflammation, diabetes, and cancer .

HY-15985A

CTX-0294885 hydrochloride 3 Publications Verification	Akt	Metabolic Disease Inflammation/Immunology Cancer
CTX-0294885 hydrochloride is a broad spectrum kinase inhibitor that can capture 235 kinases from MDA-MB-231 cells, and can capture all members of the AKT family. CTX-0294885 hydrochloride is a powerful reagent for analysis of kinome signaling networks that can be used for the research of diseases like inflammation, diabetes, and cancer .

HY-144875

CTX-712	CDK	Cancer
CTX-712 is an orally effective CLK 2 inhibitor, with an IC₅₀ of 1.4 nM, showing anti-tumor activity .

HY-17625

Acebilustat 1 Publications Verification CTX-4430	Aminopeptidase	Inflammation/Immunology
Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory agent.

HY-U00442

CTX1 1 Publications Verification	MDM-2/p53 E1/E2/E3 Enzyme	Cancer
CTX1 is a p53 activator that overcomes HdmX-mediated p53 repression. CTX1 exhibits potent anti-cancer activity in a mouse acute myeloid leukemia (AML) model system .

HY-132283

PF-9363 1 Publications Verification CTX-648	Histone Acetyltransferase	Cancer
PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer .

HY-126129

Desacetylcefotaxime	Bacterial	Infection
Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria .

HY-149772

*Ciguatoxin CTX* 3C**	Others	Neurological Disease Inflammation/Immunology
Ciguatoxin CTX 3C, an immunizing and heterologous hapten, induces a rapid imbalance in neuronal excitability .

HY-126129R

Desacetylcefotaxime (Standard)	Drug Metabolite Bacterial	Infection
Desacetylcefotaxime (Standard) is the analytical standard of Desacetylcefotaxime. This product is intended for research and analytical applications. Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria .

HY-14879A

Avibactam sodium Maximum Cited Publications 62 Publications Verification NXL-104	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and *CTX-M-15* with IC₅₀s of 8 nM and 5 nM, respectively .

HY-14879B

Avibactam sodium hydrate Maximum Cited Publications 62 Publications Verification NXL-104 hydrate	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and *CTX-M-15* with IC₅₀s of 8 nM and 5 nM, respectively .

HY-14879

Avibactam free acid Maximum Cited Publications 62 Publications Verification NXL-104 free acid	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and *CTX-M-15* with IC₅₀s of 8 nM and 5 nM, respectively .

HY-14879C

Avibactam sodium dihydrate NXL-104 dihydrate	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam sodium (NXL-104) dihydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and *CTX-M-15* with IC₅₀s of 8 nM and 5 nM, respectively .

HY-109593

BMS-813160 1 Publications Verification	CCR	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
BMS-813160 is a potent and selective CCR2/5 dual antagonist. BMS-813160 binds with CCR2 and CCR5 with IC₅₀s of 6.2 and 3.6 nM, respectively. BMS-813160 can be used for the research of inflammation .

HY-131349

CCR4-351	CCR	Cancer
CCR4-351 is an orally active, potent and selective CCR4 antagonist. CCR4-351, featuring a novel piperidinyl-azetidine motif, has IC₅₀s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4-351 has antitumor activity .

HY-131349A

CCR4-351 hydrochloride	CCR	Metabolic Disease Cancer
CCR4-351 hydrochloride is an orally active, potent and selective CCR4 antagonist. CCR4-351 hydrochloride, featuring a novel piperidinyl-azetidine motif, has IC₅₀s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4-351 hydrochloride has antitumor activity .

HY-139745

FPI-1523 sodium	Beta-lactamase Bacterial	Infection
FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with K_ds of 4 nM and 34 nM for *CTX-M-15* and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC₅₀ of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity .

HY-139745A

FPI-1523	Beta-lactamase Bacterial	Infection
FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with K_ds of 4 nM and 34 nM for *CTX-M-15* and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC₅₀ of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity .

HY-14879AR

Avibactam sodium (Standard)	Beta-lactamase Bacterial Antibiotic	Infection
Avibactam (sodium) (Standard) is the analytical standard of Avibactam (sodium). This product is intended for research and analytical applications. Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and *CTX-M-15* with IC₅₀s of 8 nM and 5 nM, respectively .

HY-125836

CCR4 antagonist 2	CCR	Endocrinology Cancer
CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits T_reg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. CCR4 antagonist 2 (Compound 31) exhibits IC₅₀ values of Ca ²⁺flux and (chemotaxis) CTX are 40 nM and 70 nM, respectively .

HY-139744

FPI-1465	Beta-lactamase Penicillin-binding protein (PBP) Bacterial	Infection
FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs).FPI-1465 inhibits PBP2 (IC₅₀=1.0 µg/mL). FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with K_ds of 0.011 and 5.3 µM, respectively .

Cat. No.	Product Name	Target	Research Area

HY-P1902

*Cardiotoxin Analog (CTX) IV (6-12)* 5+ Cited Publications	Peptides	Cardiovascular Disease
Cardiotoxin Analog (CTX) IV (6-12) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra. CTX IV is an unique snake venom cardiotoxin .

HY-P1902A

*Cardiotoxin Analog (CTX) IV (6-12) (TFA)* 5+ Cited Publications	Peptides	Others
Cardiotoxin Analog (CTX) IV (6-12) (TFA) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra. CTX IV is an unique snake venom cardiotoxin .

Cat. No.	Product Name	Target	Research Area

HY-P99179

CTX-2026	Inhibitory Antibodies	Cancer
CTX-2026 is a fully human antibody that binds to CD277. CTX-2026 shows an anti-tumor effect on ovarian tumor models. CTX-2026 can be used for the research of cancer .

HY-P99178

CTX-471	Interleukin Related	Inflammation/Immunology Cancer
CTX-471 is a fully human monoclonal antibody of CD137. CTX-471 has bind affinity for recombinant human, cynomolgus macaque CD137 and mouse CD137 with K_d values of 50 nM, 61 nM and 748 nM, respectively. CTX-471 can be used for the research of immunomodulation and cancer .

*Cardiotoxin Analog (CTX) IV (6-12)* 5+ Cited Publications	Cardiovascular Disease Natural Products Animals Source classification Disease Research Fields	Others
Cardiotoxin Analog (CTX) IV (6-12) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra. CTX IV is an unique snake venom cardiotoxin .

*Cardiotoxin Analog (CTX) IV (6-12) (TFA)* 5+ Cited Publications	Structural Classification Pyrrole Alkaloids Animals Source classification Other Diseases Disease Research Fields	Others
Cardiotoxin Analog (CTX) IV (6-12) (TFA) is a part peptide of Cardiotoxin Analog (CTX) IV. Cardiotoxin analogues IV isolated from the venom of Taiwan Cobra. CTX IV is an unique snake venom cardiotoxin .

Cat. No.	Compare	Product Name	Species	Source

HY-P71459

	*Beta-lactamase CTX-M-1/Bla Protein, E.coli (His)* bla; men1Beta-lactamase CTX-M-1; EC 3.5.2.6; Beta-lactamase MEN-1; Cefotaximase 1	E.coli	E. coli
	Beta-lactamase CTX-M-1/Bla protein is a broad-spectrum beta-lactamase that greatly contributes to antibiotic resistance by hydrolyzing penicillins and cephalosporins (including third-generation drugs). Beta-lactamase CTX-M-1/Bla Protein, E.coli (His) is the recombinant E. coli-derived Beta-lactamase CTX-M-1/Bla protein, expressed by E. coli , with N-His labeled tag.

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CTX

Inhibitors & Agonists

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