2. Anti-infection
  3. Bacterial
  4. Desacetylcefotaxime

Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria.

For research use only. We do not sell to patients.

Desacetylcefotaxime Chemical Structure

Desacetylcefotaxime Chemical Structure

CAS No. : 66340-28-1

Size Price Stock Quantity
5 mg USD 170 In-stock
10 mg USD 270 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Desacetylcefotaxime:

Desacetylcefotaxime Related Antibodies

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Description

Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria[1].

Molecular Weight

413.43

Formula

C14H15N5O6S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C(N1[C@@]([H])([C@@H](C1=O)NC(/C(C2=CSC(N)=N2)=N\OC)=O)SC3)=C3CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (604.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 250 mg/mL (604.70 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4188 mL 12.0939 mL 24.1879 mL
5 mM 0.4838 mL 2.4188 mL 4.8376 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 2.4188 mL 12.0939 mL 24.1879 mL 60.4697 mL
5 mM 0.4838 mL 2.4188 mL 4.8376 mL 12.0939 mL
10 mM 0.2419 mL 1.2094 mL 2.4188 mL 6.0470 mL
15 mM 0.1613 mL 0.8063 mL 1.6125 mL 4.0313 mL
20 mM 0.1209 mL 0.6047 mL 1.2094 mL 3.0235 mL
25 mM 0.0968 mL 0.4838 mL 0.9675 mL 2.4188 mL
30 mM 0.0806 mL 0.4031 mL 0.8063 mL 2.0157 mL
40 mM 0.0605 mL 0.3023 mL 0.6047 mL 1.5117 mL
50 mM 0.0484 mL 0.2419 mL 0.4838 mL 1.2094 mL
60 mM 0.0403 mL 0.2016 mL 0.4031 mL 1.0078 mL
80 mM 0.0302 mL 0.1512 mL 0.3023 mL 0.7559 mL
100 mM 0.0242 mL 0.1209 mL 0.2419 mL 0.6047 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Desacetylcefotaxime Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desacetylcefotaxime66340-28-1Bacterialantimicrobial activityaerobicanaerobic bacteriametabolitebrain abscessesInhibitorinhibitorinhibit

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