2. Anti-infection
  3. Beta-lactamase Bacterial
  4. FPI-1523

FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity.

For research use only. We do not sell to patients.

FPI-1523 Chemical Structure

FPI-1523 Chemical Structure

CAS No. : 1452459-50-5

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Other Forms of FPI-1523:

FPI-1523 Related Antibodies

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Description

FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity[1].

IC50 & Target

β-lactamase[1]
In Vitro

FPI-1523 inhibits K12 E. coli K12 and PBP2, with MIC and IC50 of 4 μg/mL and 0.4 μg/mL, respectively[1].
FPI-1523 inhibit E. coli BW25113 pGDP-2 transformants either with an empty vector or expressing different β-lactamases, with low MICs (1-2 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FPI-1523 Related Antibodies
Molecular Weight

322.30

Formula

C9H14N4O7S
CAS No.
SMILES

CC(NNC([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(=O)(O)=O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FPI-1523 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FPI-15231452459-50-5FPI1523FPI 1523Beta-lactamaseBacterialβ-lactamaseAvibactamCTX-M-15OXA-48PBP2antimicrobialInhibitorinhibitorinhibit

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