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Results for "

CXCL1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Natural
Products

11

Recombinant Proteins

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12927
    SX-517

    		CXCR Inflammation/Immunology
    SX-517 is a dual CXCR2/1 antagonist, containing boronic acid. SX-517 inhibits CXCL1-induced Ca 2+ flux (IC50=38 nM), and antagonizes CXCL8-induced [(35)S]GTPγS binding (IC50=60 nM) and ERK1/2 phosphorylation. SX-517 has significant ability for inflammation suppression, in both humanized polymorphonuclear (PMN) cells and in murine model [1] .
    SX-517
  • HY-163475
    CXCL-CXCR1/2-IN-1

    		CXCR Cancer
    CXCL-CXCR1/2-IN-1 is an orally active ELR +CXCL-CXCR1/2 pathway inhibitor with an EC50 of 42.7 nM for CXCR2 [1]. CXCL-CXCR1/2-IN-1 shows anticancer and antiangiogenic effects [1].
    CXCL-CXCR1/2-IN-1
  • HY-115644
    BMS-470539 dihydrochloride

    		Melanocortin Receptor Inflammation/Immunology
    BMS-470539 dihydrochloride is a highly potent and selective melanocortin-1 receptor (MC-1R) agonist with an IC50 of 120 nM, an EC50 of 28 nM. BMS-470539 dihydrochloride does not activate MC-3R and is a very weak partial agonist at MC-4R and MC-5R. BMS-470539 dihydrochloride has potently anti-inflammatory properties [1] .
    BMS-470539 dihydrochloride
  • HY-RS03383
    CXCL1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CXCL1 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CXCL1 Human Pre-designed siRNA Set A
    CXCL1 Human Pre-designed siRNA Set A
  • HY-N2573A
    Corydalmine hydrochloride

    L-Corydalmine hydrochloride; TLZ-16-CL

    		 Fungal CXCR Infection Neurological Disease
    Corydalmine hydrochloride inhibits spore germination of some plant pathogenic as well as saprophytic fungi [1]. Corydalmine hydrochloride acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine hydrochloride alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .
    Corydalmine hydrochloride
  • HY-N2573
    Corydalmine

    L-Corydalmine; TLZ-16

    		 Fungal CXCR Infection Neurological Disease
    Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi [1]. Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .
    Corydalmine

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