Search Result
Results for "
Dermatophyte
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
6
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-16246
-
|
Fungal
|
Infection
|
Haloprogin is a potent antifungal agent. Haloprogin has activity against dermatophytes, Candida spp and a limited number of Gram-positive bacteria .
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- HY-108012
-
|
Fungal
|
Infection
|
ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research .
|
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- HY-B0348
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Piritetrate; M-732
|
Fungal
|
Infection
|
Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
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- HY-B0518A
-
|
Fungal
Antibiotic
|
Infection
|
Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
|
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- HY-17643
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VT-1161
|
Fungal
Cytochrome P450
|
Infection
|
Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .
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- HY-162296
-
|
Fungal
|
Infection
|
Antibacterial agent 188 (compound 2d) is an antibacterial agent that inhibits dermatophyte activity .
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-
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- HY-118451
-
|
Fungal
|
Infection
|
Lanomycin is an antifungal compound with activity against Candida and dermatophytes .
|
-
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- HY-N3041
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Agoniadin; NSC 609065
|
Fungal
|
Infection
Cancer
|
Plumieride is an antifungal agent. Plumieride has strong fungitoxicity against some dermatophytes. Plumieride has little cytotoxic activity against the P388 leukaemia cell line with an IC50 of 85 μg/mL .
|
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- HY-17643R
-
|
Fungal
Cytochrome P450
|
Infection
|
Oteseconazole (Standard) is the analytical standard of Oteseconazole. This product is intended for research and analytical applications. Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .
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- HY-B0348R
-
|
Fungal
|
Infection
|
Liranaftate (Standard) is the analytical standard of Liranaftate. This product is intended for research and analytical applications. Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
|
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- HY-B0518AR
-
|
Fungal
Antibiotic
|
Infection
|
Naftifine (hydrochloride) (Standard) is the analytical standard of Naftifine (hydrochloride). This product is intended for research and analytical applications. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
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- HY-114518
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KP363
|
Fungal
|
Infection
|
Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as tinea pedis, tinea cruris, tinea versicolor .
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- HY-114518S2
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KP363-d4
|
Fungal
Isotope-Labeled Compounds
|
Infection
|
Butenafine-d4 (KP363-d4) is the deuterium labeled Butenafine (HY-114518). Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as ?tinea pedis, ?tinea cruris, tinea versicolor .
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- HY-121924
-
|
Bacterial
|
Infection
|
Chloracetophos is a fungicide with potential to inhibit dermatophytes .
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- HY-136767
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|
Fungal
Antibiotic
|
Infection
|
Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin completely inhibits growth of severa dermatophytes on agar medium at a concentration of 75 μg/mL .
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- HY-19584
-
|
Fungal
|
Infection
|
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .
|
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- HY-17583S
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-
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- HY-10445
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Azoline; R126638
|
Fungal
|
Infection
|
Pramiconazole is a broad-spectrum antifungal agent with oral activity. Pramiconazole has a good affinity for 14α-demethylase. Pramiconazole can be used in the study of fungal infections in the local skin, hair, nails, oral cavity, and genital mucosa .
|
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- HY-B0319
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UK-20349
|
Fungal
Antibiotic
|
Infection
|
Tioconazole (UK-20349) is an antifungal imidazole derivative with broad spectrum activity. Tioconazole has inhibitory active aginst several dermatophytes and several yeasts with MIC50s <3.12 mg/L and <9 mg/L, respectively .
|
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-
- HY-B0518AS
-
|
Fungal
Antibiotic
|
Infection
|
Naftifine-d3 (hydrochloride) is the deuterium labeled Naftifine hydrochloride. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition[1].
|
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- HY-N2472
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Castanogenin
|
Bacterial
|
Infection
|
Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .
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- HY-B0450S
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HOE296b-d11
|
Fungal
Bacterial
Ferroptosis
Autophagy
|
Infection
Cancer
|
Ciclopirox-d11 is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].
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-
-
- HY-B0450S1
-
|
Isotope-Labeled Compounds
Fungal
Bacterial
Ferroptosis
Autophagy
|
Infection
Cancer
|
Ciclopirox-d11 (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].
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-
- HY-B0319R
-
|
Fungal
Antibiotic
|
Infection
|
Tioconazole (Standard) is the analytical standard of Tioconazole. This product is intended for research and analytical applications. Tioconazole (UK-20349) is an antifungal imidazole derivative with broad spectrum activity. Tioconazole has inhibitory active aginst several dermatophytes and several yeasts with MIC50s <3.12 mg/L and <9 mg/L, respectively .
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- HY-106546
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KC 9147
|
Fungal
|
Infection
|
Tolciclate (KC 9147) is an antifungal agent with in vitro inhibitory activity against dermatophytes, effective at concentrations of 0.01-0.1 μg/mL. Tolciclate is colorless and soluble in well-tolerated excipients, and it is more lipophilic than Tolnaftate (HY-B0370). Tolciclate can be used in research related to antifungal infections .
|
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-
- HY-15660
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KP-103
|
Fungal
|
Infection
|
Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively . Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species .
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- HY-111333
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Dioxapyrrolomycin; LL-F42248α; AL-R2081
|
Others
|
Infection
|
Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.
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- HY-B0450
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HOE296b
|
Fungal
Bacterial
Ferroptosis
Autophagy
|
Infection
Inflammation/Immunology
Cancer
|
Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox also has anticancer and anti-inflammatory effect .
|
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- HY-B0450A
-
Ciclopirox ethanolamine; HOE 296
|
Fungal
Bacterial
Ferroptosis
|
Infection
Cancer
|
Ciclopirox olamine (Ciclopirox ethanolamine) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox olamine also has anticancer and anti-inflammatory effect .
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- HY-N2472R
-
|
Bacterial
|
Infection
|
Medicagenic acid (Standard) is the analytical standard of Medicagenic acid. This product is intended for research and analytical applications. Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .
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- HY-15660S
-
KP-103-d4
|
Isotope-Labeled Compounds
Fungal
|
Infection
|
Efinaconazole-d4 is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].
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- HY-B0450R
-
|
Fungal
Bacterial
Ferroptosis
Autophagy
|
Infection
Inflammation/Immunology
Cancer
|
Ciclopirox (Standard) is the analytical standard of Ciclopirox. This product is intended for research and analytical applications. Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox also has anticancer and anti-inflammatory effect .
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- HY-B0450AG
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Ciclopirox ethanolamine; HOE 296
|
Bacterial
Fungal
Ferroptosis
|
Infection
|
Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .
|
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- HY-B0450AR
-
|
Fungal
Bacterial
Ferroptosis
|
Infection
Cancer
|
Ciclopirox (olamine) (Standard) is the analytical standard of Ciclopirox (olamine). This product is intended for research and analytical applications. Ciclopirox olamine (Ciclopirox ethanolamine) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox olamine also has anticancer and anti-inflammatory effect .
|
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- HY-121772
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(+)-Actinopyrone A; SS 1538A
|
Others
|
Infection
|
Actinopyrone A is a pyrone isolated from S. pactum with diverse biological activities. It has selective and potent antimicrobial activity against H. pylori (MIC=0.1 ng/mL) with no activity against other Gram-negative bacteria including E. coli, K. pneumoniae, P. aeruginosa, and B. fragilis. Actinopyrone A also mildly inhibits growth of Gram-positive bacteria and dermatophytes with MIC values ranging from 1 Intravenous administration of actinopyrone A (30 μg/kg) increases coronary blood flow in dogs by 196.2%.
|
-
Cat. No. |
Product Name |
Type |
-
- HY-B0450AG
-
Ciclopirox ethanolamine (GMP); HOE 296 (GMP)
|
Fluorescent Dye
|
Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .
|
Cat. No. |
Product Name |
Type |
-
- HY-B0450AG
-
Ciclopirox ethanolamine (GMP); HOE 296 (GMP)
|
Biochemical Assay Reagents
|
Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-136767
-
-
-
- HY-N2472
-
-
-
- HY-N3041
-
-
-
- HY-19584
-
-
-
- HY-111333
-
Dioxapyrrolomycin; LL-F42248α; AL-R2081
|
Structural Classification
Microorganisms
Antibiotics
Source classification
|
Others
|
Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.
|
-
-
- HY-N2472R
-
|
Triterpenes
Structural Classification
Herniaria glabra Linnaeus.
Terpenoids
Plants
Caryophyllaceae
|
Bacterial
|
Medicagenic acid (Standard) is the analytical standard of Medicagenic acid. This product is intended for research and analytical applications. Medicagenic acid (Castanogenin) is isolated from the roots of Herniaria glabra, exhibits potent fungistatic effects against several plant pathogens and human dermatophytes . Medicagenic acid (Castanogenin) has low enzyme inhibitory activities, the target enzymes are xanthine oxidase, collagenase, elastase, tyrosinase, ChE .
|
-
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-15660S
-
|
Efinaconazole-d4 is the deuterium labeled Efinaconazole. Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively[1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species[1].
|
-
-
- HY-114518S2
-
|
Butenafine-d4 (KP363-d4) is the deuterium labeled Butenafine (HY-114518). Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as ?tinea pedis, ?tinea cruris, tinea versicolor .
|
-
-
- HY-17583S
-
|
Griseofulvin-d3 is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal agent[1][2].
|
-
-
- HY-B0518AS
-
|
Naftifine-d3 (hydrochloride) is the deuterium labeled Naftifine hydrochloride. Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition[1].
|
-
-
- HY-B0450S
-
|
Ciclopirox-d11 is the deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].
|
-
-
- HY-B0450S1
-
|
Ciclopirox-d11 (sodium) is deuterium labeled Ciclopirox. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic[1].
|
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