Pyrroxamycin (Synonyms: Dioxapyrrolomycin; LL-F42248α; AL-R2081)

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Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.

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Pyrroxamycin Chemical Structure

CAS No. : 105888-54-8

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Description	Pyrroxamycin is a novel antibiotic produced by Streptomyces, whose chemical structure was determined by chemical properties and X-ray crystallography and 13C NMR spectroscopy analysis. It is active against Gram-positive bacteria and dermatophytes. In this paper, the authors discuss the taxonomy, fermentation, isolation, physicochemical properties, chemical structure, and biological activity of the strain producing Pyrroxamycin.
Molecular Weight	384.00
Formula	C₁₂H₆Cl₄N₂O₄
CAS No.	105888-54-8
SMILES	O=[N+](C1=C([C@H]2OCOC3=C(Cl)C=C(Cl)C=C23)NC(Cl)=C1Cl)[O-]
Structure Classification	Antibiotics
Initial Source	Microorganisms Streptomyces sp. S46506
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Pyrroxamycin, a new antibiotic taxonomy, fermentation, isolation, structure determination and biological properties

Pyrroxamycin Related Classifications

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyrroxamycin105888-54-8Dioxapyrrolomycin LL-F42248α AL-R2081OthersInhibitorinhibitorinhibit

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Pyrroxamycin (Synonyms: Dioxapyrrolomycin; LL-F42248α; AL-R2081)

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