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MAP2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map2k1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map2k1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map2k2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K3 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K4 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K5 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map2k5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map2k5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K6 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K7 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map2k2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map2k4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents [2].
P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. P34cdc2 Kinase can phosphorylate mitogen-activated protein 2(MAP2) to regulate microtubules polymerization in Xenopus oocytes meiosis [2].
MAP4343-d4 is the deuterium labeled MAP4343. MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents[1][2][3].
SM1-71 (compound 5) is a potent TAK1 inhibitor, with a Ki of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines [2] .
EGFR-IN-119 (Compound 5l) is an inhibitor for EGFR with an IC50 of 84.3 nM. EGFR-IN-119 inhibits the cytotoxicity in lung cancer cell A549 with an IC50 of 1.34 μM. EGFR-IN-119 downregulates the expressions of EGFR, KRAS, and MAP2K genes, exhibits antioxidant activity through reduction of reactive oxygen species (ROS), and hyperpolarizes the mitochondrial membrane potential .
HRX-0233 is a small-molecule MAP2K4 inhibitor. HRX-0233 results in strong tumor shrinkage without any apparent toxicity in H358 KRASG12C-mutant non-small cell lung cancers (NSCLC) in vivo. HRX-0233 efficiently prevents feedback activation of receptor tyrosine kinases (RTKs) upon monotherapy KRAS inhibitor Sotorasib (HY-114277) and causes a more sustained and complete inhibition of MAPK signaling. HRX-0233 is promising for research of AR-negative prostate cancer, lung and colon cancers [2].
P34cdc2 Kinase Fragment is associated with the completion of DNA replication in yeast mitosis. P34cdc2 Kinase can phosphorylate mitogen-activated protein 2(MAP2) to regulate microtubules polymerization in Xenopus oocytes meiosis [2].
METAP2/Methionine aminopeptidase 2 protein removes N-terminal methionine from nascent proteins. It preferentially cleaves when the second residue is small and uncharged. METAP2 has higher catalytic activity for Met-Val peptides than METAP1, suggesting its role in processing Met-Val and Met-Thr sequences in vivo. It also protects EIF2S1 from phosphorylation by inhibitory kinases, regulating protein synthesis. METAP2/Methionine aminopeptidase 2 Protein, Human (Sf9, His) is the recombinant human-derived METAP2/Methionine aminopeptidase 2 protein, expressed by Sf9 insect cells , with N-6*His labeled tag.
The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K6 Protein, Human (Baculovirus, His) is the recombinant human-derived MAP2K6 protein, expressed by Sf9 insect cells , with N-6*His labeled tag.
MAP2K7 protein is a dual-specificity kinase involved in the MAP kinase signal transduction pathway. MAP2K7 Protein, Human (Sf9) is the recombinant human-derived MAP2K7 protein, expressed by Sf9 insect cells , with tag free. The total length of MAP2K7 Protein, Human (Sf9) is 418 a.a., .
MAP2K7 protein is a dual-specificity kinase involved in the MAP kinase signal transduction pathway. MAP2K7 Protein, Human (Sf9, His, GST) is the recombinant human-derived MAP2K7 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAP2K7 Protein, Human (Sf9, His, GST) is 418 a.a., .
The MAP2K4 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K4 Protein, Human (P. pastoris, His-GST) is the recombinant human-derived MAP2K4 protein, expressed by P. pastoris , with N-6*His, N-GST labeled tag. The total length of MAP2K4 Protein, Human (P. pastoris, His-GST) is 398 a.a., with molecular weight of 71.5 kDa.
The MAP2K4 protein is a dual-specificity kinase involved in the MAP kinase pathway. MAP2K4 Protein, Human (Sf9) is the recombinant human-derived MAP2K4 protein, expressed by Sf9 insect cells , tag free.
METAP2, also known as methionine aminopeptidase 2, plays a critical role in protein synthesis by co-translationally removing N-terminal methionine from nascent proteins. This enzymatic activity is particularly pronounced when the second residue in the primary sequence is small and uncharged (including residues such as Ala, Cys, Gly, Pro, Ser, Thr, or Val). METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) is the recombinant mouse-derived METAP2/Methionine aminopeptidase 2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) is 477 a.a., with molecular weight of ~60 kDa.
ERK1 protein is an important serine/threonine kinase in the MAP kinase pathway and cooperates with MAPK1/ERK2 to activate the MAPK/ERK cascade. Stimulated by KIT and KITLG/SCF, this pathway plays a key role in cell growth, adhesion, survival, and differentiation. ERK1 Protein, Human (GST) is the recombinant human-derived ERK1 protein, expressed by E. coli , with N-GST labeled tag. The total length of ERK1 Protein, Human (GST) is 378 a.a., .
The MEK1 protein is a dual-specificity kinase that plays a crucial role in the MAP kinase pathway.MEK1 regulates various cellular processes such as growth, adhesion, survival, and differentiation, as well as transcription, metabolism, and cytoskeletal rearrangements.MEK1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived MEK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.
The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MKK6 Protein, Human (sf9) is the recombinant human-derived MKK6 protein, expressed by Sf9 insect cells , with tag free. The total length of MKK6 Protein, Human (sf9) is 334 a.a., with molecular weight of ~37 kDa.
The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MKK6 Protein, Human (sf9, His-GST) is the recombinant human-derived MKK6 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of MKK6 Protein, Human (sf9, His-GST) is 334 a.a., with molecular weight of ~60 kDa.
The MKK6 protein is a dual-specificity kinase involved in the MAP kinase pathway. MKK6 Protein, Human (S207D, T211D, sf9) is the recombinant human-derived MKK6 protein, expressed by Sf9 insect cells , with tag free. The total length of MKK6 Protein, Human (S207D, T211D, sf9) is 334 a.a., with molecular weight of ~38 kDa.
Ragulator Complex Protein LAMTOR3; Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3; MEK-Binding Partner 1; Mp1; Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1; Mitogen-Activated Protein Kinase Scaffold Protein 1; LAMTOR3; MAP2K1IP
The MAPKSP1 protein, also known as porphobilinogen deaminase (HMBS), is crucial in the heme biosynthetic pathway and catalyzes the sequential polymerization of four porphobilinogen molecules to form hydroxymethyl bixane. The process begins with the assembly of the dipyrromethane cofactor of porphobilinogen or preuroporphyrinogen. MAPKSP1 Protein, Human (His) is the recombinant human-derived MAPKSP1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of MAPKSP1 Protein, Human (His) is 124 a.a., with molecular weight of ~15.0 kDa.
MAP4343-d4 is the deuterium labeled MAP4343. MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents[1][2][3].
Microtubule associated protein 2; MAP2A; MAP2B; MAP2C
WB, ICC/IF, IHC-P
Human, Mouse, Rat
MAP2 Antibody is an unconjugated, approximately 60 kDa, rabbit-derived, anti-MAP2 polyclonal antibody. MAP2 Antibody can be used for: WB, IF-Cell, IHC-P expriments in human, mouse, rat background without labeling.
phospho-ERK1 + 2 (Thr183/Tyr185) Antibody is an unconjugated, approximately 42/44 kDa, rabbit-derived, anti-phospho-ERK1 + 2 (Thr183/Tyr185) polyclonal antibody. phospho-ERK1 + 2 (Thr183/Tyr185) Antibody can be used for: WB, ELISA, IHC-P, IHC-F, ICC, IF expriments in human, mouse, and predicted: rat, chicken, dog, cow, horse, rabbit, guinea pig background without labeling.
Phospho-MEK1 (Ser298) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Ser298). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.
Phospho-MEK1 (Thr292) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Thr292). It can be used for WB assays with tag free, in the background of Mouse, Rat.
Phospho-MEK4 (Ser80) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 44 kDa, targeting to Phospho-MEK4 (Ser80). It can be used for WB,IP assays with tag free, in the background of Human.
MEK7 Antibody (YA2647) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2647), targeting MEK7, with a predicted molecular weight of 47 kDa (observed band size: 47 kDa). MEK7 Antibody (YA2647) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.
MAP2K6 Antibody (YA1088) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1088), targeting MAP2K6, with a predicted molecular weight of 37 kDa (observed band size: 40 kDa). MAP2K6 Antibody (YA1088) can be used for WB, IP experiment in human, rat background.
MEK3/MEK6 Antibody (YA3323) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3323), targeting MEK3/MEK6, with a predicted molecular weight of 39,37 kDa (observed band size: 39,37 kDa). MEK3/MEK6 Antibody (YA3323) can be used for WB, ICC/IF, IP experiment in human, mouse background.
MEK5 Antibody (YA3140) is a biotin-conjugated non-conjugated IgG antibody, targeting MEK5, with a predicted molecular weight of 50 kDa. MEK5 Antibody (YA3140) can be used for WB, ICC/IF experiment in human background.
MEK2 Antibody (YA3059) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3059), targeting MEK2, with a predicted molecular weight of 44 kDa (observed band size: 44 kDa). MEK2 Antibody (YA3059) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.
MEK3 Antibody (YA3214) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3214), targeting MEK3, with a predicted molecular weight of 39 kDa (observed band size: 38-40 kDa). MEK3 Antibody (YA3214) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.
MAP2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map2k1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map2k1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map2k2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K3 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K4 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K5 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map2k5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map2k5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K6 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
MAP2K7 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP2K7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Map2k2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Map2k4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map2k4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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