MEK2 Antibody (YA3059)

MEK2 Antibody (YA3059) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3059), targeting MEK2, with a predicted molecular weight of 44 kDa (observed band size: 44 kDa). MEK2 Antibody (YA3059) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.

The protein encoded by The related gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. The kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of The kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in The related gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of The kinase is also found to be involved in the pathorelated genesis of Yersinia and anthrax. A pseudorelated gene, which is located on chromosome 7, has been identified for The related gene.

5605

Predicted band size: 44 kDa; Observed band size: 44 kDa

Affinity Purified

Non-conjugated

Unmodified

Signal Transduction

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse

P36507

WB: 1/500-1/1000;IHC: 1/50-1/100;IF: 1/50-1/200;IP: 1/20

WB, IHC-F, IHC-P, ICC/IF, IP

Liquid

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthetic peptide of human MEK2