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Results for "

Nematicidal

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Peptides

5

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-121325
    Fervenulin

    		Parasite Infection
    Fervenulin has nematicidal activity and inhibits egg hatch and J2 mortality of M. incognita with MICs of 30 μg/mL and 120 μg/mL, respectively .
    Fervenulin
  • HY-116090
    Conoidin A

    		Parasite Infection Cardiovascular Disease Neurological Disease
    Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 µM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII) . Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease .
    Conoidin A
  • HY-163780
    AChE-IN-66

    		Parasite Infection
    Nematicidal agent 1 is a potent nematicidal agent. Nematicidal agent 1 binds to the pocket of acetylcholine esterase (AChE) .
    AChE-IN-66
  • HY-N3754
    Dihydropinosylvin monomethyl ether

    		Parasite Infection
    Dihydropinosylvin monomethyl ether is a natrual compound with nematicidal activity. Dihydropinosylvin monomethyl ether can inhibit pine wood nematodes infection .
    Dihydropinosylvin monomethyl ether
  • HY-123897
    Chamaejasmenin C

    		Parasite Infection
    Chamaejasmenin C, a biflavanone, shows nematicidal activity against second-stage juveniles (J2s) of B. xylophilus and B. mucronatus .
    Chamaejasmenin C
  • HY-N1621
    1-Deacetylnimbolinin B

    		Fungal Parasite Infection
    1-Deacetylnimbolinin B is a nimbolinin-type limonoid isolated from the fruits of Melia toosendan. Limonoids are a class of highly oxygenated nortriterpenoids that exhibit insecticidal, antifungal, nematicidal and cytotoxic properties .
    1-Deacetylnimbolinin B
  • HY-P5957
    Omphalotin A

    		Parasite Infection
    Omphalotin A is a cyclic peptide, and shows nematicidal activity .
    Omphalotin A
  • HY-125596
    Lachnumon

    		Parasite Infection
    Lachnumon is a fungal metabolite with nematicidal and antimicrobial activities .
    Lachnumon
  • HY-159959
    cis-3-Indoleacrylic acid

    		Proton Pump Others
    cis-3-Indoleacrylic acid is a nematicidal compound that can be isolated from Streptomyces youssoufiensis YMF3.862. cis-3-Indoleacrylic acid is also a V‑ATPase inhibitor, and inhibits V-ATPase expression and enzyme activity. cis-3-Indoleacrylic acid causes Meloidogyne incognita juveniles to have swollen bodies with apparent cracks on the cuticle surface (LC50: 16.31 μg/mL). cis-3-Indoleacrylic acid inhibits H + accumulation in nematode bodies .
    cis-3-Indoleacrylic acid
  • HY-138074
    Milbemycin A4 oxime

    5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime

    		 Parasite Infection
    Milbemycin A4 oxime (5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime) is a derivative of Milbemycin A4 (HY-126906) and a component of Milbemycin oxime (HY-B0778), both of which have insecticidal and nematicidal activities. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae in naturally infected dogs with D. immitis and inhibits the growth of clinical isolates of Candida glabrata (MIC80=16-32 μg/mL). Milbemycin A4 oxime (2.5 μg/mL) blocks the efflux of Fluconazole (HY-B0101) from clinical isolates of Candida glabrata. Milbemycin A4 oxime enhances doxorubicin-induced cell growth inhibition and increases the intracellular accumulation of doxorubicin and P-glycoprotein substrate Rhodamine 123 (HY-D0816) in doxorubicin-resistant but not sensitive MCF-7 breast cancer cells in a concentration-dependent manner.
    Milbemycin A4 oxime

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