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  4. Pinaceae

Pinaceae

 

Pinaceae (95):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N6939
    Pseudolaric Acid B 82508-31-4 99.47%
    Pseudolaric Acid B is a diterpene isolated from the root of Pseudolarix kaempferi (pinaceae), has anti-cancer, antifungal, and antifertile activities, and shows immunosuppressive activity on T lymphocytes. Pseudolaric Acid B inhibits hepatitis B virus (HBV) secretion through apoptosis and cell cycle arrest. Pseudolaric Acid B induces autophagy.
    Pseudolaric Acid B
  • HY-101795
    Larixyl acetate 4608-49-5 99.46%
    Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction.
    Larixyl acetate
  • HY-N6871
    Abietic acid 514-10-3
    Abietic acid, an orally active diterpene isolated from Colophony, displays significant anti-proliferative, anti-inflammatory, anti-obesity effect, bacteriostatic, cell cycle arresting and pro-apoptotic activities. Abietic acid inhibits lipoxygenase activity for allergy. Abietic acid enhances cell migration and tube formation in HUVECs. Abietic acid induces significant angiogenic potential, which is associated with upregulation of extracellular signal-regulated kinase (ERK) and p38 expression. Abietic acid attenuates sepsis-induced lung injury by inhibiting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway to inhibit M1 macrophage polarization. Abietic acid exhibits a positive effect against liver injury by attenuating inflammation and ferroptosis. Abietic acid shows accelerated wound closure in a mouse model of cutaneous wounds. Abietic acid significantly reduces the proliferation and growth of NSCLC cells by IKKβ inhibition.Additionally, Abietic acid ameliorates psoriasis-like inflammation and modulates gut microbiota in mice. Abietic acid is promising for research in non-small-cell lung cancer (NSCLC), liver injury-related deseases and psoriasis.
    Abietic acid
  • HY-N2071
    Cedrol 77-53-2 ≥98.0%
    Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, insecticidal, and anti-fungal activities.
    Cedrol
  • HY-N0349
    Methyl paraben 99-76-3 99.86%
    Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury.
    Methyl paraben
  • HY-N3268
    Methyl pseudolarate A 82508-33-6
    Methyl pseudolarate A is a diterpenoid compound that exerts its antitumor activity by inhibiting cell proliferation and inducing apoptosis.
    Methyl pseudolarate A
  • HY-N0349R
    Methyl paraben (Standard) 99-76-3
    Methyl paraben (Standard) is the analytical standard of Methyl paraben. This product is intended for research and analytical applications. Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury.
    Methyl paraben (Standard)
  • HY-N0803R
    Myrcene (Standard) 123-35-3
    Myrcene (Standard) is the analytical standard of Myrcene. This product is intended for research and analytical applications. Myrcene (β-Myrcene) is a type of aromatic compound that inhibits TNFα and NF-κB activity. Myrcene has anti-invasive action, inhibits cell cycle, and leads to cancer cell apoptosis. Myrcene has strong blood protection effect, anti-inflammation, and anti-inflammatory activity.
    Myrcene (Standard)
  • HY-110028
    Leelamine hydrochloride 16496-99-4 99.06%
    Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor, which is known to regulate fatty acid synthesis[2,3].
    Leelamine hydrochloride
  • HY-N0803
    Myrcene 123-35-3
    Myrcene (β-Myrcene) is a type of aromatic compound that inhibits TNFα and NF-κB activity. Myrcene has anti-invasive action, inhibits cell cycle, and leads to cancer cell apoptosis. Myrcene has strong blood protection effect, anti-inflammation, and anti-inflammatory activity.
    Myrcene
  • HY-N1775
    3',4'-Dihydroxyacetophenone 1197-09-7 99.92%
    3',4'-Dihydroxyacetophenone (3,4-DHAP), isolated from Picea Schrenkiana Needles exhibits a strong suppressive action against tyrosinase activity, with an IC50 of 10 μM. 3',4'-Dihydroxyacetophenone (3,4-DHAP) is a vasoactive agent and antioxidant.
    3',4'-Dihydroxyacetophenone
  • HY-135190
    (-)-Cedrene 469-61-4 ≥98.0%
    (-)-Cedrene (α-cedrene) is a sesquiterpene constituent of cedarwood oils, with anti-leukemic, antimicrobial and anti-obesity activities.
    (-)-Cedrene
  • HY-N3062
    Pinobanksin 548-82-3 98.63%
    Pinobanksin has apoptotic induction in a B-cell lymphoma cell line.
    Pinobanksin
  • HY-N3463
    Isopimaric acid 5835-26-7 ≥99.0%
    Isopimaric acid is a potent opener of large conductance calcium activated K+ (BK) channels.
    Isopimaric acid
  • HY-N9086
    Poriol 14348-16-4 98.91%
    Poriol is a flavonoid isolated from Pseudotsuga sinensis.
    Poriol
  • HY-W109613
    Methyl dehydroabietate 1235-74-1 99.89%
    Methyl dehydroabietate is a kind of resin acid that can be isolated from spruce bark. Methyl dehydroabietate has antimicrobial activities.
    Methyl dehydroabietate
  • HY-119546
    Pinolenic acid 16833-54-8 ≥98.0%
    Pinolenic acid (PNLA) is a polyunsaturated fatty acid that can be isolated from Pinus orientalis and Pinus pinaster seed oil. Pinolenic acid has anti-inflammatory and lipid-lowering activities.
    Pinolenic acid
  • HY-N0672
    Pseudolaric Acid C 82601-41-0 99.59%
    Pseudolaric C is a diterpenoid isolated from the root bark of Pseudolarix amabilis, has antifungal activity.
    Pseudolaric Acid C
  • HY-N10418
    Isorhapontin 32727-29-0 98.42%
    Isorhapontin is an antifungal agent. Isorhapontin inhibits the hydrolytic activity of Trichoderma cellobiohydrolase I (CBH I) with a Ki of 57.2 μM. Isorhapontin also inhibits the activity of Trichoderma endoglucanase I.
    Isorhapontin
  • HY-N2865
    Amaronol B 226561-02-0
    Amaronol B is an auronol that can be isolated from the bark of Pseudolarix amabilis.
    Amaronol B