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  4. Meliaceae

Meliaceae

 

Meliaceae (100):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19356
    Rocaglamide 84573-16-0 99.34%
    Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia.
    Rocaglamide
  • HY-Y1787
    Dimethyl malonate 108-59-8 99.92%
    Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis.
    Dimethyl malonate
  • HY-N0263
    Toosendanin 58812-37-6 98.77%
    Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities.
    Toosendanin
  • HY-116035
    Nimbolide 25990-37-8 99.72%
    Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways.
    Nimbolide
  • HY-126741
    Azadirachtin 11141-17-6 99.06%
    Azadirachtin is an oral active triterpenoid compound with anticancer, antimalarial, anti-inflammatory, and insecticidal activities. Azadirachtin induces cell apoptosis through the mitochondrial pathway (by inhibiting Bcl-2/Bax ratio or activating Apaf-1 and caspase-3) or through death receptors (by inhibiting TNFR activation). Additionally, Azadirachtin exerts its anti-inflammatory effects by inhibiting NF-кB signaling pathway activation, and it exhibits insecticidal activity by inducing apoptosis in insect cells.
    Azadirachtin
  • HY-126741R
    Azadirachtin (Standard) 11141-17-6
    Azadirachtin (Standard) is the analytical standard of Azadirachtin. This product is intended for research and analytical applications. Azadirachtin, one of the most promising botanical insecticides, is widely used for pest control. Azadirachtin induces apoptosis in insect cell lines, including Sf9, SL-1 and BTI-Tn-5B1-4.
    Azadirachtin (Standard)
  • HY-N10507
    Methyl 14-methylpentadecanoate 5129-60-2
    Methyl 14-methylpentadecanoate is an ester product.
    Methyl 14-methylpentadecanoate
  • HY-126589
    Rohitukin 62653-92-3
    Rohitukin is a limonoid, which can be isolated from Turraea obtusifolia. Rohitukin is an antagonist for insect hormone 20-hydroxyecdysone (20-E) with ED50 of 125 μM. Rohitukin explains the strategy for plants defend against insect predation, and can be used for research about insect control.
    Rohitukin
  • HY-19355
    Rocagloic acid 190385-15-0
    Rocagloic acid is a racaglamide derivative isolated from the fruits of Aglaia elliptifolia with potent cytotoxicity.
    Rocagloic acid
  • HY-N7694
    Isotoosendanin 97871-44-8 99.51%
    Isotoosendanin is a limonoid that can be isolated from Melia toosendan fruit. Isotoosendanin displays significant anti-inflammatory and analgesic activities.
    Isotoosendanin
  • HY-15359
    Episilvestrol 697235-39-5 99.86%
    Episilvestrol is a derivative of silvestrol, isolated from the fruits and twigs of Aglaia perviridis, and is a specific eIF4A-targeting translation inhibitor, with antitumor activity.
    Episilvestrol
  • HY-N11958
    5-Hydroxy-3,6,7,4'-tetramethoxyflavone 14787-34-9 99.76%
    5-Hydroxy-3,6,7,4'-tetramethoxyflavone is a natural compound isolated from Aglaia edulis.
    5-Hydroxy-3,6,7,4'-tetramethoxyflavone
  • HY-N1281
    Sendanolactone 64929-59-5
    Sendanolactone is a new tetracyclic triterpenoid from the bark of M. azedarach L. var. japonica Makino.
    Sendanolactone
  • HY-N1342
    Rocaglaol 147059-46-9
    Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells.
    Rocaglaol
  • HY-N3349
    Lyoniresinol 14464-90-5 99.32%
    Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM.
    Lyoniresinol
  • HY-N5104
    Clemaphenol A 362606-60-8 99.77%
    Clemaphenol A is a chemical constituent of the flower of Fritillaria pallidiflora.
    Clemaphenol A
  • HY-W001251
    3,5-Dimethoxybenzoic acid 1132-21-4 99.66%
    3,5-Dimethoxybenzoic acid, isolated from Melia azedarach L. leaves with antifungal activity, is an intermediate in organic synthesis.
    3,5-Dimethoxybenzoic acid
  • HY-N1284
    Seneganolide 301530-12-1
    Seneganolide (compound 1) is isolated from the stem bark of Khaya senegalensis. Seneganolide can be used as insect antifeedant.
    Seneganolide
  • HY-124941
    7-Deacetylgedunin 10314-90-6
    7-Deacetylgedunin is an activator of Keap1/Nrf2/HO-1. 7-Deacetylgedunin alleviates mice mortality induced by LPS. 7-Deacetylgedunin inhibits Keap1 expression and suppresses macrophage proliferation. 7-Deacetylgedunin suppresses inflammation in vivo and in vitro.
    7-Deacetylgedunin
  • HY-156241
    Meliadubin B
    Meliadubin B is a natural triterpenoid with significant inflammatory inhibition effect toward superoxide anion generation in human neutrophils (EC50 of 5.54 μM). Meliadubin B inhibits inducible nitric oxide synthase. Meliadubin B shows remarkable inhibition against the rice pathogenic fungus Magnaporthe oryzae with IC50 of 182.50 μM.
    Meliadubin B