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Results for "

Nonreplicating

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1355A
    Oxyphenbutazone

    		COX Bacterial Infection Inflammation/Immunology
    Oxyphenbutazone is a Phenylbutazone (HY-B0230) metabolite, with anti-inflammatory effect. Oxyphenbutazone is an orally active non-selective COX inhibitor. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis .
    Oxyphenbutazone
  • HY-162142
    BB2-50F

    		Bacterial Infection
    BB2-50F is a potent and multi-targeting bioenergetic bactericidal inhibitor of M. tuberculosis and can sterilizes replicating and non-replicating M. tuberculosis. BB2-50F inhibits succinate oxidation, decreases the activity of the tricarboxylic acid (TCA) cycle, and results in succinate secretion from M. tuberculosis.
    BB2-50F
  • HY-164793
    TGFBR1-IN-2

    		TGF-β Receptor Cytochrome P450 Bacterial Infection
    TGFBR1-IN-2 (Compound AQA) is a TGFBR1 inhibitor and an antibacterial agent. TGFBR1-IN-2 is a substrate for cytochrome P450s. TGFBR1-IN-2 contains the pyridyl-6-methyl moiety necessary for Mycobacterium tuberculosis inhibition and has potent inhibitory activity against non-replicating and persistent Mycobacterium tuberculosis .
    TGFBR1-IN-2
  • HY-108050
    4-Hydroxyoxyphenbutazone

    		Bacterial Infection Inflammation/Immunology
    4-Hydroxyoxyphenbutazone kills both replicating and nonreplicating (NR) Mycobacterium tuberculosis (Mtb), including Mtb resistant to standard agents. 4-Hydroxyoxyphenbutazone is a potent inhibitor of cytokine production. 4-Hydroxyoxyphenbutazone is an immunosuppressive agent and has the potential for rheumatoid arthritis research .
    4-Hydroxyoxyphenbutazone
  • HY-B1355
    Oxyphenbutazone monohydrate

    		Bacterial COX Infection Inflammation/Immunology
    Oxyphenbutazone monohydrate is a Phenylbutazone (HY-B0230) metabolite, with anti-inflammatory effect. Oxyphenbutazone monohydrate is an orally active non-selective COX inhibitor. Oxyphenbutazone monohydrate selectively kills non-replicating Mycobaterium tuberculosis .
    Oxyphenbutazone monohydrate
  • HY-B1355R
    Oxyphenbutazone (monohydrate) (Standard)

    		Bacterial COX Infection Inflammation/Immunology
    Oxyphenbutazone (monohydrate) (Standard) is the analytical standard of Oxyphenbutazone (monohydrate). This product is intended for research and analytical applications. Oxyphenbutazone monohydrate is a Phenylbutazone (HY-B0230) metabolite, with anti-inflammatory effect. Oxyphenbutazone monohydrate is an orally active non-selective COX inhibitor. Oxyphenbutazone monohydrate selectively kills non-replicating Mycobaterium tuberculosis .
    Oxyphenbutazone (monohydrate) (Standard)
  • HY-B1355AS1
    Oxyphenbutazone-13C6

    		Isotope-Labeled Compounds COX Bacterial Infection Inflammation/Immunology Cancer
    Oxyphenbutazone- 13C6 is the 13C6 labeled Oxyphenbutazone (HY-B1355A). Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is the metabolite of Phenylbutazone (HY-B0230). Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2].
    Oxyphenbutazone-13C6
  • HY-136348
    ML338

    		Bacterial Infection
    ML338 is a selective small molecule inhibitor probe of non-replicating Mycobacterium tuberculosis bacilli and is against the non-replicating M. tuberculosis with IC90 and IC99 values of 1 μM and 4 μM, respectively by CFU. ML338 is a invaluable tool for identifying both essential functions and vulnerabilities of the M. tuberculosis bacilli in the nutrient deprivation states. ML338 can be used for the study of M. tuberculosis chemotherapy .
    ML338

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