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Results for "

PRP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Amyloid-β (1) Apoptosis (1) Fluorescent Dye (4) NF-κB (1) PACAP Receptor (1) Parasite (1) Prostaglandin Receptor (1) Protease Activated Receptor (PAR) (2) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (4) Cardiovascular Disease (3) Infection (6) Inflammation/Immunology (1) Neurological Disease (4)
Oligonucleotides:	Pre-designed siRNA Sets (2) siRNAs (2)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107662

*TCS PrP* Inhibitor 13**	Apoptosis	Infection Cancer
TCS PrP Inhibitor 13, an antiprion agent, is a cellular prion protein (PrP ^C) inhibitor. TCS PrP Inhibitor 13, as a protease-resistant form of prion protein (PrP-res) accumulation inhibitor, shows an IC₅₀ value of 3 nM in both ScN2a and F3 cell lines. TCS PrP Inhibitor 13 induces Schwannoma cells apoptosis .

HY-139201

Poly-D-lysine hydrobromide (MW 30000-70000)	Others	Cancer
Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide (MW 30000-70000) removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrP ^C .

HY-139201A

Poly-D-lysine hydrobromide (MW 70000-150000)	Others	Cancer
Poly-D-lysine hydrobromide (MW 70000-150000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide (MW 70000-150000) removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrP ^C .

HY-RS11219

PRPS1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PRPS1 Human Pre-designed siRNA Set A contains three designed siRNAs for PRPS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PRPS1 Human Pre-designed siRNA Set A PRPS1 Human Pre-designed siRNA Set A

HY-RS11220

PRPS2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PRPS2 Human Pre-designed siRNA Set A contains three designed siRNAs for PRPS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PRPS2 Human Pre-designed siRNA Set A PRPS2 Human Pre-designed siRNA Set A

HY-100857

PrPSc-IN-1	Fluorescent Dye	Neurological Disease
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrP ^Sc, inhibits its accumulation, with an IC₅₀ of 1.6 μM. Anti-prion activity .

HY-136102

*Py-ds-Prp-Osu*	ADC Linker	Cancer
Py-ds-Prp-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P1511

*PACAP-Related Peptide (PRP), human*	PACAP Receptor	Neurological Disease
PACAP-Related Peptide (PRP), human is a 29 amino-acid region of the PACAP precursor protein.

HY-163341

PAR4 antagonist 1	Protease Activated Receptor (PAR)	Cardiovascular Disease
PAR4 antagonist 1 (Compound 48) is a protease activated receptor 4 (PAR4) antagonist with an IC₅₀ of 1.8 nM. PAR4 antagonist 1 has an IC₅₀ of 2 nM against γ-thrombin-activated PAR4 in platelet-rich plasma (PRP). PAR4 antagonist 1 can be used in antithrombotic research .

HY-147702

BB 0305179	Others	Infection Neurological Disease
BB 0305179 (compound 59) is a potent anti-prion agent, with an IC₅₀ of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain . BB 0305179 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-115360

IND45193	Others	Others
IND45193 is a compound used to inhibit prion disease, with activity in reducing PrP(Sc) levels. In cells infected with prions, IND45193 can reduce PrP(Sc) levels, and its activity was determined through screening of multiple cell types and concentration-effect relationship studies.

HY-P0019

Z-Gly-Gly-Arg-AMC Maximum Cited Publications 9 Publications Verification	Fluorescent Dye	Cardiovascular Disease
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-P0019A

Z-Gly-Gly-Arg-AMC acetate Maximum Cited Publications 9 Publications Verification	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-138865

BiCAPPA	Others	Infection
BiCAPPA is the first bivalent antiprion ligand. BiCAPPA can decrease infectious conformational form of prion protein (PrP ^Sc) from scrapie-infected cells, with an EC₅₀ of 0.32 μM .

HY-147371

Quinoprazine	Parasite	Infection Neurological Disease
Quinoprazine is a potent inhibitor of Vaccinia virus DNA synthesis with an IC₅₀ value of 10 μM. Quinoprazine has antimalarial activity against Plasmodium berghei and also displays antiprion potency, significantly decreases PrP ^{S ^c} levels ^- .

HY-P0019B

Z-Gly-Gly-Arg-AMC TFA	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AMC TFA is the TFA salt form of Z-Gly-Gly-Arg-AMC (HY-P0019). Z-Gly-Gly-Arg-AMC TFA is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) .

HY-128345

UDM-001651	Protease Activated Receptor (PAR)	Cardiovascular Disease
UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC₅₀=4 nM; K_d=1.4 nM). UDM-001651 shows antiplatelet potency (IC₅₀=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP) .

HY-D0939

Direct Blue 1 Chicago Sky Blue 6B	Amyloid-β NF-κB	Inflammation/Immunology
Direct Blue 1 (Chicago Sky Blue 6B) is a complex dye for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1 is a potent and competitive VGLUT inhibitor. Direct Blue 1 can inhibit the Aβ-binding small molecule PrP ligand. Direct Blue 1 has anti-inflammatory activity .

HY-128039

17-Phenyl-ω-trinor-PGE2	Prostaglandin Receptor	Others
17-Phenyl-ω-trinor-PGE2 is a PGE2 (HY-101952) analog, which is an agonist for EP1 and EP3 receptor. 17-Phenyl-ω-trinor-PGE2 inhibits the PAF-induced aggregation of human platelet-rich plasma (PRP) and Cicaprost (HY-19583) induced Cyclic AMP (HY-B1511) production .

Cat. No.	Product Name	Type

HY-P0019

Z-Gly-Gly-Arg-AMC 5+ Cited Publications	Chromogenic Substrates
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-P0019A

Z-Gly-Gly-Arg-AMC acetate 5+ Cited Publications	Chromogenic Substrates
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-D0939

Direct Blue 1 Chicago Sky Blue 6B	Dyes
Direct Blue 1 (Chicago Sky Blue 6B) is a complex dye for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1 is a potent and competitive VGLUT inhibitor. Direct Blue 1 can inhibit the Aβ-binding small molecule PrP ligand. Direct Blue 1 has anti-inflammatory activity .

Cat. No.	Product Name	Target	Research Area

HY-P0305

PrP (106-126) Prion protein (106-126)	Peptides	Infection
PrP (106-126) is a peptide corresponding to the prion protein (PrP) amyloidogenic region, and its biochemical properties resemble the infectious form of prion protein.

HY-P0019

Z-Gly-Gly-Arg-AMC Maximum Cited Publications 9 Publications Verification	Fluorescent Dye	Cardiovascular Disease
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-P0019A

Z-Gly-Gly-Arg-AMC acetate Maximum Cited Publications 9 Publications Verification	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

HY-P1511

*PACAP-Related Peptide (PRP), human*	PACAP Receptor	Neurological Disease
PACAP-Related Peptide (PRP), human is a 29 amino-acid region of the PACAP precursor protein.

HY-P0019B

Z-Gly-Gly-Arg-AMC TFA	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AMC TFA is the TFA salt form of Z-Gly-Gly-Arg-AMC (HY-P0019). Z-Gly-Gly-Arg-AMC TFA is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) .

Cat. No.	Product Name	Target	Research Area

HY-P990167

*Anti-Mouse/Human PrP/prion protein Antibody (TW1)*	Inhibitory Antibodies	Others
Anti-Mouse/Human PrP/prion protein Antibody (TW1) is a mouse-derived IgG2a type antibody inhibitor, targeting to mouse/human PrP/prion protein.

HY-P990030

Ralzapastotug AB-308	Inhibitory Antibodies	Infection
Ralzapastotug (AB-308) is a monoclonal antibody targeting amino acids 106-126 of the cellular prion protein PrP ^C .

Species:	Human (5) Mouse (1)
Tag:	His (1) GST (2) Fc (3)
Source:	HEK293 (3) Sf9 insect cells (2) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P74619

	PRNP/CD230 Protein, Human (HEK293, Fc) Major prion protein; CD230; ALTPRP; PRIP; PRP	Human	HEK293
	Although its primary function is unknown, the PRNP/CD230 protein has been implicated in multiple neuronal processes, including neuronal development, synaptic plasticity, and myelin homeostasis. PRNP acts as an agonist of the ADGRG6 receptor and promotes the maintenance of myelin. PRNP/CD230 Protein, Human (HEK293, Fc) is the recombinant human-derived PRNP/CD230 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78023

	PRNP/CD230 Protein, Mouse (HEK293, Fc) Major prion protein; PRP; ALTPRP; PRIP; PRP; PRNP	Mouse	HEK293
	The PRNP/CD230 protein is involved in multiple cellular processes and may affect neuronal development, synaptic plasticity, and myelin maintenance.It promotes myelin homeostasis, induces apoptosis, and interacts with other proteins.PRNP/CD230 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived PRNP/CD230 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74619A

	PRNP/CD230 Protein, Human (HEK293, hFc) Major prion protein; CD230; ALTPRP; PRIP; PRP	Human	HEK293
	Although its primary function is unknown, the PRNP/CD230 protein has been implicated in multiple neuronal processes, including neuronal development, synaptic plasticity, and myelin homeostasis. PRNP acts as an agonist of the ADGRG6 receptor and promotes the maintenance of myelin. PRNP/CD230 Protein, Human (HEK293, Fc) is the recombinant human-derived PRNP/CD230 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P703003

	PRPF4B Protein, Human (sf9, GST) KIAA0536; PRP4; PRP4B; PRP4H; PRPF4K	Human	Sf9 insect cells
	PRPF4B Protein, Human (sf9, GST) is the recombinant human-derived PRPF4B, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P703021

	PRPF19 Protein, Human (sf9, GST) NMP200; PRP19; SNEV	Human	Sf9 insect cells
	PRPF19 Protein, Human (sf9, GST) is the recombinant human-derived PRPF19, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P71464

	Peroxiredoxin-2/PRDX2 Protein, Human (His) Epididymis secretory sperm binding protein Li 2a; HEL S 2a; MGC4104; Natural killer cell enhancing factor B; Natural killer cell-enhancing factor B; Natural Killer Enhancing Factor B; NKEF B; NKEF-B; NKEFB; Peroxiredoxin 2; Peroxiredoxin-2; PRDX 2; PRDX2; PRP; PRX2; PRXII; PTX1; TDPX1; Thiol Specific Antioxidant 1 ; Thiol specific antioxidant protein; Thiol-specific antioxidant protein; Thioredoxin Dependent Peroxide Reductase 1; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1; Torin; TPX1; TSA	Human	E. coli
	Peroxiredoxin-2 (PRDX2) is a thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides, which is essential for cellular protection against oxidative stress. It detoxifies peroxide, senses hydrogen peroxide-mediated signaling events, and may participate in signaling cascades initiated by growth factors and tumor necrosis factor-alpha. Peroxiredoxin-2/PRDX2 Protein, Human (His) is the recombinant human-derived Peroxiredoxin-2/PRDX2 protein, expressed by E. coli , with N-His labeled tag. The total length of Peroxiredoxin-2/PRDX2 Protein, Human (His) is 197 a.a., with molecular weight of ~25.8 kDa.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82763

	Calcineurin A Antibody (YA2508) PPP3CA; CALNA; CNA; Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform	WB, ICC/IF, FC	Human, Mouse, Rat
	Calcineurin A Antibody (YA2508) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2508), targeting Calcineurin A, with a predicted molecular weight of 59 kDa (observed band size: 59 kDa). Calcineurin A Antibody (YA2508) can be used for WB, ICC/IF, FC experiment in human, mouse, rat background.

HY-P82012

	PRPF4 Antibody (YA1757) PRP4; RP70; HPRP4; PRP4p; HPRP4P; SNRNP60	WB, IP	Human, Mouse
	PRPF4 Antibody (YA1757) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1757), targeting PRPF4, with a predicted molecular weight of 58 kDa (observed band size: 58 kDa). PRPF4 Antibody (YA1757) can be used for WB, IP experiment in human, mouse background.

HY-P83313

	PRPF19 Antibody (YA3058) PRPF19; NMP200; PRP19; SNEV; Pre-mRNA-processing factor 19; Nuclear matrix protein 200; PRP19/PSO4 homolog; hPso4; Senescence evasion factor	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	PRPF19 Antibody (YA3058) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3058), targeting PRPF19, with a predicted molecular weight of 55 kDa (observed band size: 55 kDa). PRPF19 Antibody (YA3058) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

HY-P82014

	PRPF8 Antibody (YA1759) HPRP8; p220; PRP8; PRPC8; PRPf8; RP13; SNRNP220	WB, IHC-P	Human
	PRPF8 Antibody (YA1759) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1759), targeting PRPF8, with a predicted molecular weight of 274 kDa (observed band size: 274 kDa). PRPF8 Antibody (YA1759) can be used for WB, IHC-P experiment in human background.

HY-P81980

	Prion Protein Antibody (YA1725) CJD; GSS; PRP; PRNP; ASCR; KURU; PRIP; PRPc; CD230; AltPRP; Prion protein; PRP27-30; PRP33-35C	WB, IHC-P	Human, Mouse, Rat
	Prion Protein Antibody (YA1725) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1725), targeting Prion Protein, with a predicted molecular weight of 28 kDa (observed band size: 28 kDa). Prion Protein Antibody (YA1725) can be used for WB, IHC-P experiment in human, mouse, rat background.

HY-P82128

	C4 Binding Protein Antibody (YA1873) C4BP; C4BPB; PRP	WB, IHC-P, ICC/IF, IP	Human, Rat
	C4 Binding Protein Antibody (YA1873) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1873), targeting C4 Binding Protein, with a predicted molecular weight of 28 kDa (observed band size: 45 kDa). C4 Binding Protein Antibody (YA1873) can be used for WB, IHC-P, ICC/IF, IP experiment in human, rat background.

HY-P82733

	SF3A3 Antibody (YA2478) splicing factor 3a subunit 3; PRP9; PRPF9; SAP61; SF3a60	WB	Human, Mouse, Rat, Hamster
	SF3A3 Antibody (YA2478) is a biotin-conjugated non-conjugated IgG antibody, targeting SF3A3, with a predicted molecular weight of 59 kDa (observed band size: 59 kDa). SF3A3 Antibody (YA2478) can be used for WB experiment in human, mouse, rat, hamster background.

HY-P83423

	CDC40 Antibody (YA3168) cell division cycle 40; EH-binding protein 3; EHB3; pre-mRNA splicing factor 17; PRP17; PRPF17; Cdc40	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	CDC40 Antibody (YA3168) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3168), targeting CDC40, with a predicted molecular weight of 66 kDa (observed band size: 74 kDa). CDC40 Antibody (YA3168) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.

HY-P81840

	Peroxiredoxin 2 Antibody (YA1585) PRDX2; NKEFB; TDPX1; Peroxiredoxin-2; Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1	WB, IHC-P	Human, Mouse, Rat
	Peroxiredoxin 2 Antibody (YA1585) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1585), targeting Peroxiredoxin 2, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). Peroxiredoxin 2 Antibody (YA1585) can be used for WB, IHC-P experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-RS11219

PRPS1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
PRPS1 Human Pre-designed siRNA Set A contains three designed siRNAs for PRPS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS11220

PRPS2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
PRPS2 Human Pre-designed siRNA Set A contains three designed siRNAs for PRPS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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