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  3. Z-Gly-Gly-Arg-AMC

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Z-Gly-Gly-Arg-AMC Chemical Structure

Z-Gly-Gly-Arg-AMC Chemical Structure

CAS No. : 66216-78-2

Size Price Stock Quantity
5 mg USD 119 In-stock
10 mg USD 168 In-stock
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100 mg   Get quote  

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Based on 9 publication(s) in Google Scholar

Other Forms of Z-Gly-Gly-Arg-AMC:

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Description

Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

Molecular Weight

579.60

Formula

C28H33N7O7

CAS No.
Appearance

Solid

Color

White to off-white

Emission (Em)

480

Excitation (Ex)

390

Sequence

Z-Gly-Gly-{Arg-AMC}

Sequence Shortening

ZGG-{Arg-AMC}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 40 mg/mL (69.01 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7253 mL 8.6266 mL 17.2533 mL
5 mM 0.3451 mL 1.7253 mL 3.4507 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7253 mL 8.6266 mL 17.2533 mL 43.1332 mL
5 mM 0.3451 mL 1.7253 mL 3.4507 mL 8.6266 mL
10 mM 0.1725 mL 0.8627 mL 1.7253 mL 4.3133 mL
15 mM 0.1150 mL 0.5751 mL 1.1502 mL 2.8755 mL
20 mM 0.0863 mL 0.4313 mL 0.8627 mL 2.1567 mL
25 mM 0.0690 mL 0.3451 mL 0.6901 mL 1.7253 mL
30 mM 0.0575 mL 0.2876 mL 0.5751 mL 1.4378 mL
40 mM 0.0431 mL 0.2157 mL 0.4313 mL 1.0783 mL
50 mM 0.0345 mL 0.1725 mL 0.3451 mL 0.8627 mL
60 mM 0.0288 mL 0.1438 mL 0.2876 mL 0.7189 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Z-Gly-Gly-Arg-AMC
Cat. No.:
HY-P0019
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