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SAOS-2

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108639
    MIRA-1

    NSC 19630

    		 MDM-2/p53 Apoptosis Cancer
    MIRA-1 is a maleimide analogue. MIRA-1 can induce apoptosis in mutant p53 cells via restoration of p53-dependent transcriptional transactivation. MIRA-1 has anticancer activity .
    MIRA-1
  • HY-108477
    TMPyP4 tosylate
    2 Publications Verification

    TMP 1363

    		 G-quadruplex Telomerase Cholinesterase (ChE) SARS-CoV Cancer
    TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand. TMPyP4 tosylate inhibits the interaction between G-quadruplexes and IGF-1. TMPyP4 tosylate is a telomerase inhibitor and inhibits cancer cells proliferation. TMPyP4 tosylate is also a stabilizer of nucleic acid secondary structure and an acetylcholinesterase inhibitor. Besides, TMPyP4 tosylate has antiviral activity against SARS-CoV-2 [2] .
    TMPyP4 tosylate
  • HY-116926
    Deoxynybomycin

    		Antibiotic Bacterial DNA/RNA Synthesis Topoisomerase Infection Cancer
    Deoxynybomycin is an antibiotic, that can be isolated from Streptomyces, and antibacterial activity against Staphylococcus aureus. Deoxynybomycin is the inhibitor for DNA gyrase and Topoisomerase I. Deoxynybomycin induces expression of p21/WAF1, exhibits cytotoxicity and induces apoptosis in cancer cells Saos-2, TMK-1, and THP-1 [2].
    Deoxynybomycin
  • HY-161082
    Topoisomerase I inhibitor 12

    		Topoisomerase Cancer
    Topoisomerase I inhibitor 12 (compound 12), a Camptothecin (HY-16560)-based derivative, is a potent Topoisomerase I inhibitor. Topoisomerase I inhibitor 12 shows anticancer activity .
    Topoisomerase I inhibitor 12

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